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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 68280Generated: October 26, 2026

N,N'-Diphenylbenzidine

Diphenylbenzidine · DFRR · N,N'-DiphenyL · DEPHENYLBENZIDINE · TIMTEC-BB SBB002946 · Benzidine, N,N'-diph · N'-Diphenylbenzidine · N,N-Diphenylbenzidne

https://huagongshe.com/en/chemical/68280

N,N'-Diphenylbenzidine molecular structure

Identifiers & Physical Properties

CAS No.531-91-9
Molecular formulaC24H20N2
Average molar mass336.4 g/mol
Monoisotopic mass336.16264864 g/mol
SMILESc1ccc(Nc2ccc(-c3ccc(Nc4ccccc4)cc3)cc2)cc1
InChIKeyFDRNXKXKFNHNCA-UHFFFAOYSA-N
PubChem CID68280
EC No.208-521-7
DTXSIDDTXSID0060197

Chemical & Physical Properties

XLogP6.6
Topological polar surface area24.1
Hydrogen bond donors2
Hydrogen bond acceptors2
Rotatable bonds5
Heavy atoms26
Formal charge0
Complexity343
Chemical classesNitrogen Compounds -> Benzidine and Derivatives
Physical DescriptionSolid[Merck Index] Grey odorless powder[Alfa Aesar MSDS]
Melting point246-248 °C(lit.)
Boiling point462.9°C (rough estimate)
Density1.1750 (rough estimate)
Vapor density11.6 (vs air)
Refractive index1.7620 (estimate)
Flash point>110°C
Storage conditionsStore below +30°C.
SolubilityAcetone (Slightly), DMF (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly, Sonicated)Insoluble in water.
Physical stateFine Crystalline Powder
pKa (acidity coefficient)1.31±0.40(Predicted)
ColorGray to brownish
SensitivityLight Sensitive
Merck14,3319
BRN2220993
InChI1S/C24H20N2/c1-3-7-21(8-4-1)25-23-15-11-19(12-16-23)20-13-17-24(18-14-20)26-22-9-5-2-6-10-22/h1-18,25-26H
InChIKeyFDRNXKXKFNHNCA-UHFFFAOYSA-N
SMILESN(c1ccccc1)c2ccc(cc2)-c3ccc(Nc4ccccc4)cc3
CAS DataBase Reference531-91-9(CAS DataBase Reference)
FDA UNII8IO8V406YP
NIST Chemistry Reference[1,1'-Biphenyl]-4,4'-diamine, n,n'-diphenyl-(531-91-9)
EPA Substance Registry System[1,1'-Biphenyl]-4,4'-diamine, N,N'-diphenyl- (531-91-9)
UNSPSC Code12352116
NACRESNA.22
GHS pictogramGHS07,GHS08
Signal wordWarning
GHS hazard statementsH302+H312+H332-H351
GHS precautionary statementsP201-P202-P261-P264-P270-P271-P280-P301+P312+P330-P302+P352+P312+P362+P364-P304+P340+P312-P308+P313-P405-P501
Personal protective equipment (PPE)Eyeshields, Gloves, type N95 (US)
Hazard symbolsXi
Safety statements (S)22-24/25
UN transport number2811
Water hazard class (WGK)3
F8
TSCA inventory statusTSCA listed
Hazard class6.1(b)
Packing groupIII
Customs code29215900
Storage class11 - Combustible Solids

Safety & Regulations

GHS classificationWarningH302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]P203, P261, P264, P270, P271, P280, P301+P317, P302+P352, P304+P340, P317, P318, P321, P330, P362+P364, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 2 reports by companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Regulatory informationChemical: [1,1'-Biphenyl]-4,4'-diamine, N,N'-diphenyl-[1,1'-Biphenyl]-4,4'-diamine, N,N'-diphenyl-: Does not have an individual approval but may be used under an appropriate group standard
Hazards summaryMay cause irritation[Alfa Aesar MSDS] See Benzidine and Diphenylamine.
Hazard Classes and CategoriesAcute Tox. 4 (100%)
F8
Personal protective equipment (PPE)Eyeshields, Gloves, type N95 (US)
Water hazard class (WGK)3
TSCA inventory statusTSCA listed
UN transport number2811
Customs code29215900
Signal wordWarning
GHS pictogramGHS07,GHS08
Hazard symbolsXi
Safety statements (S)22-24/25
Hazard class6.1(b)
Storage class11 - Combustible Solids
Packing groupIII
GHS hazard statementsH302+H312+H332-H351
GHS precautionary statementsP201-P202-P261-P264-P270-P271-P280-P301+P312+P330-P302+P352+P312+P362+P364-P304+P340+P312-P308+P313-P405-P501

Applications & Uses

Uses

N,N'-Diphenylbenzidine is an indicator suitable for redox titrations, e.g. with dichromate or cerium(IV) sulfate 1,2. It is also used as intermediates in organic synthesis.

Uses

See diphenylamine.