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Basic information
- CAS
86-34-0- Standard SMILES
CN1C(=O)CC(c2ccccc2)C1=O- InChIKey
WLWFNJKHKGIJNW-UHFFFAOYSA-N- Molecular formula
- C11H11NO2
- Average molar mass
- 189.21 g/mol
- Monoisotopic mass
- 189.07897859
Names & identifiers
- Preferred name
- Phensuximide
- IUPAC
- 1-methyl-3-phenylpyrrolidine-2,5-dione
- English name
- PHENSUXIMIDE
- Molecular formula
- C11H11NO2
- Molecular weight
- 189.21
Names & synonyms
Phensuximide86-34-0MilontinSuccitimalLifeneEpimid1-methyl-3-phenylpyrrolidine-2,5-dionePhensuximidMilontonMirontin1-Methyl-3-phenyl-2,5-pyrrolidinedioneFensuccimide
Show more names
pm334LifenPM 334EpimalMirotin
PhensuximidumFensuximidaSuccinimide, N-methyl-2-phenyl-1-Methyl-3-PhenylsuccinimideN-Methyl-alpha-phenylsuccinimideDTXSID40234602,5-Pyrrolidinedione, 1-methyl-3-phenyl-PM-334
Database identifiers
- CAS
86-34-0- PubChem CID
- 6839
- DTXSID
DTXSID4023460- ChEMBL
CHEMBL797- ChEBI
CHEBI:8079- UNII
- 6WVL9C355G
- EC Number
- 201-664-6
- Nikkaji
- J4.938G
Properties
Computed structural propertiesFilling in
- XLogP
- 0.8
- Topological polar surface area
- 37.4 Ų
- Hydrogen bond donors
- 0
- Hydrogen bond acceptors
- 2
- Rotatable bonds
- 1
- Heavy atoms
- 14
- Formal charge
- 0
- Complexity
- 256
Physicochemical properties
- Melting point
- 71 · 71-73°
- Boiling point
- 324.47 °C · 324.47°C (rough estimate)
- Density
- 1.1596 · 1.1596 (rough estimate)
- refractive index
- 1.5012 · 1.5012 (estimate)
- storage temp.
- Refrigerator
- solubility
- Chloroform (Slightly), Ethyl Acetate (Slightly)
- form
- Solid
- pka
- -1.86 · -1.86±0.40(Predicted)
- color
- White to Off-White
- Water Solubility
- 4.2 g/L · 4.2g/L(25 ºC)
- EWG's Food Scores
- 1 · 1
- FDA UNII
- 6 WVL9C355G · 6WVL9C355G
- ATC code
- 3 AD02 · N03AD02
- Symbol(GHS)
- 7 · GHS07
- Signal word
- Warning
- Hazard statements
- 302 · H302
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
Safety data
- hs_code
- 2925190100
- Toxicity
- LD50 orally in mice: 960 mg/kg (Chen, Ensor)
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- Hazard statements
- H302
- Precautionary statements
- P301+P312+P330
Chemistry & industry
Applications
DescriptionPhensuximide is an anticonvulsant. It inhibits seizures induced by maximal electroshock (MES) and pentylenetetrazole in mice (ED50s = 112 and 50 mg/kg, respectively). Phensuximide (1.25 mmol/kg, i.p.) induces proteinuria and hematuria in rats. Formulations containing phensuximide have been used in the treatment of petit mal seizures.
UsesPhensuximide, like ethosuximide, is an anticonvulsant drug used in minor forms of epilepsy.
UsesPhensuximide is an anticonvulsant drug, used in the treatment of neurological disorders stemming from the brain. Antiepileptic.
Upstream & downstream products
Upstream raw materials
Downstream products
Suppliers
Related reactions
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Compound notes
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