Basic information
- CAS
575-74-6- Standard SMILES
CCCCNC(=O)c1ccc(Cl)cc1O- InChIKey
ZGJHIFYEQJEUKA-UHFFFAOYSA-N- Molecular formula
- C11H14ClNO2
- Average molar mass
- 227.69 g/mol
- Monoisotopic mass
- 227.0713064
Overview
Buclosamide is a member of salicylamides.
Names & identifiers
- Preferred name
- Buclosamide
- IUPAC
- N-butyl-4-chloro-2-hydroxybenzamide
- English name
- Buclosamide
- Molecular formula
- C11H14ClNO2
- Molecular weight
- 227.69
Names & synonyms
Buclosamide575-74-6BuclosamidaBuclosamidumO52NM0A9YLBuclosamide [INN:BAN:DCF]N-Butyl-4-chlorsalicylamideDTXSID50206111Buclosamide (INN:BAN:DCF)JaditRefChem:121817DTXCID50128602
Show more names
FungitDemycin3004 BUCLOSAMIDEBenzamide, N-butyl-4-chloro-2-hydroxy-
4-chloro-2-hydroxybenzoic acid-n-butylmide209-390-9n-Butyl-4-chloro-2-hydroxybenzamideN-Butyl-4-chlorosalicylamideSR-01000945227Buclosamidum [INN-Latin]UNII-O52NM0A9YLBuclosamida [INN-Spanish]
Database identifiers
- CAS
575-74-6- PubChem CID
- 68466
- DTXSID
DTXSID50206111- ChEMBL
CHEMBL348251- ChEBI
CHEBI:134935- UNII
- O52NM0A9YL
- EC Number
- 209-390-9
- Nikkaji
- J6.559E
Properties
Computed structural properties
- XLogP
- 3.3
- Topological polar surface area
- 49.3 Ų
- Hydrogen bond donors
- 2
- Hydrogen bond acceptors
- 2
- Rotatable bonds
- 4
- Heavy atoms
- 15
- Formal charge
- 0
- Complexity
- 211
Experimental & physicochemical properties
Chemical ClassesOther Classes -> Halogenated Salicylanilides
Physicochemical properties
- Melting point
- 90 · 90-92°
- Boiling point
- 366.6 · 366.6±32.0 °C(Predicted)
- Density
- 1.1769 · 1.1769 (rough estimate)
- refractive index
- 1.55 · 1.5500 (estimate)
- pka
- 7.43 · 7.43±0.35(Predicted)
- FDA UNII
- 52 NM0A9YL · O52NM0A9YL
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
Hazard information
Hazards Summary
The halogenated salicylanilides may cause photoallergic contact dermatitis (PACD). Patients with PACD note the appearance of a eczematous rash, usually on the face, neck, dorsum of the hands, and sun-exposed areas on the arms with sparing of areas under the chin and upper eyelids. [LaDou, p. 334]
Toxicology
Adverse EffectsDermatotoxin - PACD (photoallergic contact dermatitis).
Chemistry & industry
Uses & manufacturing
UsesClassification Code: Antifungal agents [NLM, ChemIDplus]
Upstream & downstream products
Upstream raw materials
Suppliers13 total
Hebei Chuanghai Biotechnology Co., Ltd+86-17732866630 · [email protected]
Career Henan Chemica Co+86-0371-86658258 +86-13203830695 · [email protected]
Dayang Chem (Hangzhou) Co.,Ltd.+86-0571-88938639 17705817739 · [email protected]
韶关市启程生物科技有限公司18122215013 · [email protected]
南京多隆生物科技有限公司18905173768 · [email protected]
BOC Sciences16314854226; +8616314854226 · [email protected]
陕西缔都医药化工有限公司029-029-81120477 17792793610 · [email protected]
上海陶术生物科技股份有限公司13564774135 · [email protected]
杭州洁汉化工有限公司+86-571-86217390; +8618058761490 · [email protected]
Nanjing Dolon Biotechnology Co.,Ltd.18905173768 · [email protected]
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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