Ethyl phosphorochloridite

HCID 68530CAS 589-57-1
Substructure searchFind similar structures

Basic information

Standard SMILES
CCOP(Cl)OCC
InChIKey
TXHWYSOQHNMOOU-UHFFFAOYSA-N
Molecular formula
C4H10ClO2P
Average molar mass
156.55 g/mol
Monoisotopic mass
156.01069387

Names & identifiers

Preferred name
Ethyl phosphorochloridite
IUPAC
chloro(diethoxy)phosphane
English name
DIETHYL CHLOROPHOSPHITE
Molecular formula
C4H10ClO2P
Molecular weight
156.55

Names & synonyms

Diethyl chlorophosphite589-57-1Diethyl phosphorochloriditeEthyl phosphorochloriditeChlorodiethoxyphosphinePhosphorochloridous acid, diethyl esterEthyl chlorophosphitediethylchlorophosphonitePhosphorochloridous acid diethyl esterF414S3V8K6EINECS 209-652-2DIETHOXYCHLOROPHOSPHINE
Show more names
orophosphiteAURORA KA-1221dlethylchlorophosphiteChlorodiethyl phosphiteDiethyl chloridophosphite
DTXSID0060430DIETHYL PHOSPHOROCHLORIDITE [MI]RefChem:596378DTXCID1042493209-652-2InChI=1/C4H10ClO2P/c1-3-6-8(5)7-4-2/h3-4H2,1-2Hchloro(diethoxy)phosphanediethylchlorophosphite

Database identifiers

CAS
589-57-1
PubChem CID
68530
DTXSID
DTXSID0060430
UNII
F414S3V8K6
EC Number
209-652-2
Nikkaji
J6.751B

Properties

Computed structural properties

XLogP
1.5
Topological polar surface area
18.5 Ų
Hydrogen bond donors
0
Hydrogen bond acceptors
2
Rotatable bonds
4
Heavy atoms
8

Experimental & physicochemical properties

SpringerMaterials PropertiesOptical coefficient

Physicochemical properties

Melting point
25 °C · 25°C
Boiling point
153 · 153-155 °C (lit.) 56-57.5 °C/30 mmHg (lit.)
Density
1.089 g/mL · 1.089 g/mL at 20 °C (lit.)
refractive index
20 · n20/D 1.434(lit.)
Flash point
34 °F · 34 °F
storage temp.
2 · 2-8°C

Safety & regulation

GHS classification

GHS Classification · 4 items

Danger

H225 (91.1%): Highly Flammable liquid and vapor [Danger Flammable liquids]

P210, P233, P240, P241, P242, P243, P260, P261, P264, P271, P280, P301+P330+P331, P302+P361+P354, P303+P361+P353, P304+P340, P305+P354+P338, P316, P319, P321, P363, P370+P378, P403+P233, P403+P235, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 45 reports by companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Hazard information

Regulatory InformationChemical: Phosphorochloridous acid, diethyl ester
Hazard Classes and CategoriesFlam. Liq. 2 (91.1%)

Safety data

F
10-21
PPE
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
wgk
3
tsca
TSCA listed
ridadr
UN 2924 3/PG 2
hs_code
29209085

Chemistry & industry

Uses & manufacturing

General Manufacturing InformationPhosphorochloridous acid, diethyl ester: ACTIVE
Applications · 3 items

UsesDiethyl chlorophosphite acts as a versatile phosphorylating agent for ester and lactone enolates, amines and alkenols. It is used in the synthesis of organophosphates and are considered anticholinesterase agents through observation in studies.

UsesDiethyl Chlorophosphite is used in the synthesis of organophosphates and are considered anticholinesterase agents through observation in studies.

UsesIn peptide synthesis.

Upstream & downstream products

Suppliers50 total

山东玖玥生物科技有限公司15553333686
国药集团化学试剂有限公司86-21-63210123 · [email protected]
梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
阿诺西（上海）生物技术有限公司400-1107768 15058188853 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]

Related reactions

47 records
New reaction record

Linked notes

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