Fenquizone
Basic information
- CAS
20287-37-0- Standard SMILES
NS(=O)(=O)c1cc2c(cc1Cl)NC(c1ccccc1)NC2=O- InChIKey
DBDTUXMDTSTPQZ-UHFFFAOYSA-N- Molecular formula
- C14H12ClN3O3S
- Average molar mass
- 337.8 g/mol
- Monoisotopic mass
- 337.0287901
Overview
Fenquizone is a member of quinazolines.
Names & identifiers
- Preferred name
- Fenquizone
- IUPAC
- 7-chloro-4-oxo-2-phenyl-2,3-dihydro-1H-quinazoline-6-sulfonamide
- English name
- fenquizone
- Molecular formula
- C14H12ClN3O3S
- Molecular weight
- 337.78
Names & synonyms
Fenquizone20287-37-0IdroloneFenquizonaFenquizonumM.G. 13054LJ1U13R8IKMG-130542-Phenyl-6-sulfonamido-7-chloro-1,2,3,4-tetrahydro-4-quinazolidoneRefChem:598915C03BA13243-689-5
Show more names
Fenquizone, 10 mM in DMSOFenquizone (1.0mg/ml in DMSO)7-Chloro-1,2,3,4-tetrahydro-4-oxo-2-phenyl-6-quinazolinesulfonamide6-Quinazolinesulfonamide, 7-chloro-1,2,3,4-tetrahydro-4-oxo-2-phenyl-
7-chloro-4-oxo-2-phenyl-2,3-dihydro-1H-quinazoline-6-sulfonamide7-chloro-4-oxo-2-phenyl-1,2,3,4-tetrahydroquinazoline-6-sulfonamideFenchizoneFenchizone [DCIT]Fenquizone [USAN:INN]Fenquizonum [INN-Latin]Fenquizona [INN-Spanish]UNII-LJ1U13R8IK
Database identifiers
- CAS
20287-37-0- PubChem CID
- 68548
- DTXSID
DTXSID10864933- ChEMBL
CHEMBL2106186- ChEBI
CHEBI:135435- UNII
- LJ1U13R8IK
- EC Number
- 243-689-5
- Nikkaji
- J10.959B
Properties
Computed structural properties
- XLogP
- 1.8
- Topological polar surface area
- 110 Ų
- Hydrogen bond donors
- 3
- Hydrogen bond acceptors
- 5
- Rotatable bonds
- 2
- Heavy atoms
- 22
- Formal charge
- 0
- Complexity
- 530
Physicochemical properties
- Melting point
- 310 ° · >310°
- Density
- 1.469 · 1.469±0.06 g/cm3(Predicted)
- storage temp.
- -20 °C · Amber Vial, -20°C Freezer, Under inert atmosphere
- solubility
- DMSO (Slightly), Methanol (Slightly, Heated)
- pka
- 9.98 · 9.98±0.60(Predicted)
- form
- Solid
- color
- Off-White to Light Beige
- Stability
- Moisture Sensitive
- FDA UNII
- 1 U13R8IK · LJ1U13R8IK
- ATC code
- 3 BA13 · C03BA13
Chemistry & industry
Pharmacology
ATC Code
C - Cardiovascular system
QC - Cardiovascular system
MeSH Pharmacological ClassificationAgents that promote the excretion of urine through their effects on kidney function.
Applications
UsesDiuretic.
UsesFenquizone is a thiazide-like diuretic commonly used for antihypertensive therapy.
Additional notes
DefinitionChEBI: Fenquizone is a member of quinazolines.
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