Basic information
- CAS
23076-35-9- Standard SMILES
Cc1cccc(C)c1NC1=NCCCS1.Cl- InChIKey
QYEFBJRXKKSABU-UHFFFAOYSA-N- Molecular formula
- C12H17ClN2S
- Average molar mass
- 256.8 g/mol
- Monoisotopic mass
- 256.0800974
Overview
Xylazine hydrochloride is the hydrochloride salt of xylazine. It is used as a sedative, analgesic, and muscle relaxant in veterinary medicine. It has a role as an emetic, an analgesic, an alpha-adrenergic agonist, a sedative and a muscle relaxant. It contains a xylazine(1+).
Names & identifiers
- Preferred name
- Xylazine Hydrochloride
- IUPAC
- N-(2,6-dimethylphenyl)-5,6-dihydro-4H-1,3-thiazin-2-amine;hydrochloride
Names & synonyms
Xylazine hydrochloride23076-35-9Xylazine HClCelactalXylazine chlorideTranquivedXylamedAnasedBAY 1470 hydrochlorideXylazin hydrochlorideRometar5,6-Dihydro-2-(2,6-xylidino)-4H-1,3-thiazine hydrochloride
Show more names
NGC3S0882SBAY-VA-14702-(2,6-Dimethylphenylamino)-4H-5,6-dihydro-1,3-thiazine hydrochloride4H-1,3-Thiazin-2-amine, N-(2,6-dimethylphenyl)-5,6-dihydro-, monohydrochlorideDTXSID6040248CHEBI:149566SedazineXylazine HCl Injection
Database identifiers
- CAS
23076-35-9- PubChem CID
- 68554
- DTXSID
DTXSID6040248- ChEMBL
CHEMBL1256022- ChEBI
CHEBI:149566- UNII
- NGC3S0882S
- EC Number
- 245-417-0
Properties
Computed structural properties
- Topological polar surface area
- 49.7 Ų
- Hydrogen bond donors
- 2
- Hydrogen bond acceptors
- 2
- Rotatable bonds
- 2
- Heavy atoms
- 16
- Formal charge
- 0
- Complexity
- 230
Experimental & physicochemical properties
Animal DrugsFDA approved animal drugs -> Active ingredient
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
This chemical does not meet GHS hazard criteria for 1.2% (1 of 80) of reports.
Danger
H301 (95%): Toxic if swallowed [Danger Acute toxicity, oral]
P261, P264, P264+P265, P270, P271, P273, P280, P301+P316, P302+P352, P304+P340, P305+P351+P338, P305+P354+P338, P317, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 80 reports by companies from 15 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Hazard information
Regulatory InformationXylazine hydrochloride: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.
Other Safety InformationIMAP assessments - 4H-1,3-Thiazin-2-amine, N-(2,6-dimethylphenyl)-5,6-dihydro-, monohydrochloride: Environment tier I assessment
Hazard Classes and CategoriesAcute Tox. 3 (95%)
Chemistry & industry
Pharmacology
MeSH Pharmacological Classification
Compounds capable of relieving pain without the loss of CONSCIOUSNESS.
Drugs used to induce drowsiness or sleep or to reduce psychological excitement or anxiety.
A heterogeneous group of drugs used to produce muscle relaxation, excepting the neuromuscular blocking agents. They have their primary clinical and therapeutic uses in the treatment of muscle spasm and immobility associated with strains, sprains, and injuries of the back and, to a lesser degree, injuries to the neck. They have been used also for the treatment of a variety of clinical conditions that have in common only the presence of skeletal muscle hyperactivity, for example, the muscle spasms that can occur in MULTIPLE SCLEROSIS. (From Smith and Reynard, Textbook of Pharmacology, 1991, p358)
Compounds that bind to and activate ADRENERGIC ALPHA-2 RECEPTORS.
Uses & manufacturing
Use ClassificationVeterinary Drug -> ADRENOCEPTOR_AGONIST -> JECFA Functional Classes
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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