Basic information
- CAS
67227-55-8- Standard SMILES
Cc1ccccc1OCC(O)CNCCn1cc(C)c(=O)[nH]c1=O- InChIKey
RETPFDTUCPKFEC-UHFFFAOYSA-N- Molecular formula
- C17H23N3O4
- Average molar mass
- 333.4 g/mol
- Monoisotopic mass
- 333.16885622
Overview
Primidolol is an aromatic ether.
Names & identifiers
- Preferred name
- Primidolol
- IUPAC
- 1-[2-[[2-hydroxy-3-(2-methylphenoxy)propyl]amino]ethyl]-5-methylpyrimidine-2,4-dione
- English name
- Primidolol
- Molecular formula
- C17H23N3O4
- Molecular weight
- 333.38
Names & synonyms
Primidolol67227-55-8PrimidololumUK-11,443UK-1144356QH73D78KDTXSID00438401-(2-((2-hydroxy-3-(2-methylphenoxy)propyl)amino)ethyl)-5-methyl-pyrimidine-2,4-dione1-[2-[[2-hydroxy-3-(2-methylphenoxy)propyl]amino]ethyl]-5-methyl-pyrimidine-2,4-dione2,4(1H,3H)-pyrimidinedione, 1-(2-((2-hydroxy-3-(2-methylphenoxy)propyl)amino)ethyl)-5-methyl-, monohydrochlorideRefChem:868508DTXCID8023840
Show more names
UK-111-[2-[[2-Hydroxy-3-(o-tolyloxy)propyl]amino]ethyl]-5-methylpyrimidine-2,4(1H,3H)-dione2,4(1H,3H)-Pyrimidinedione, 1-[2-[[2-hydroxy-3-(2-methylphenoxy)propyl]amino]ethyl]-5-methyl-1-(2-{[2-hydroxy-3-(2-methylphenoxy)propyl]amin o}ethyl)-5-methyl-1,2,3,4-tetrahydropyrimidine-2,4 -dione
Primidolol (USAN/INN)1-[2-[[2-hydroxy-3-(2-methylphenoxy)propyl]amino]ethyl]-5-methylpyrimidine-2,4-dione1-(2-((2-Hydroxy-3-(o-tolyloxy)propyl)amino)ethyl)thymineUK 11443-01UK-11443-01AC1Q6CGKPrimidololum [INN-Latin]1-[2-[[2-Hydroxy-3-(O-tolyloxy)propyl]amino]ethyl]thymine
Properties
Computed structural properties
- XLogP
- 0.6
- Topological polar surface area
- 90.9 Ų
- Hydrogen bond donors
- 3
- Hydrogen bond acceptors
- 5
- Rotatable bonds
- 8
- Heavy atoms
- 24
- Formal charge
- 0
- Complexity
- 480
Physicochemical properties
- FDA UNII
- 56 QH73D78K · 56QH73D78K
- Symbol(GHS)
- 7 · GHS07
- Signal word
- Warning
- Hazard statements
- 335 · H335-H315-H319
- Precautionary statements
- 264 · P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
Warning
H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)
The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.
Hazard information
Hazard Classes and CategoriesSkin Irrit. 2 (100%)
Safety data
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- Hazard statements
- H335-H315-H319
- Precautionary statements
- P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P
Chemistry & industry
Applications
UsesAntihypertensive; anti-anginal; cardiac depressant (anti-arrhythmic).
Suppliers5 total
南京世洲生物科技有限公司025-025-85560043 17301488900 · [email protected]
上海陶术生物科技股份有限公司+1-781-999-5354; +1-00000000000 · [email protected]
上海陶术生物科技股份有限公司13564774135 · [email protected]
TargetMol中国（陶术生物）15002134094 · [email protected]
南京世洲生物科技有限公司18351873721 · [email protected]
Additional notes
DefinitionChEBI: Primidolol is an aromatic ether.
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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