Basic information
- CAS
51213-99-1- Standard SMILES
CN(C)c1cccc(F)c1C(=O)NC(=O)Nc1ccc(Cl)cc1- InChIKey
SRLPZQAEBMZCIJ-UHFFFAOYSA-N- Molecular formula
- C16H15ClFN3O2
- Average molar mass
- 335.76 g/mol
- Monoisotopic mass
- 335.0836826
Overview
Clanfenur is a small molecule drug. Clanfenur has a monoisotopic molecular weight of 335.08 Da.
Names & identifiers
- Preferred name
- Clanfenur
- IUPAC
- N-[(4-chlorophenyl)carbamoyl]-2-(dimethylamino)-6-fluorobenzamide
- English name
- Clanfenur
- Molecular formula
- C16H15ClFN3O2
- Molecular weight
- 335.76
Names & synonyms
Clanfenur51213-99-1ClanfenurumKAM54NKT1Q1-(2-Fluoro-6-dimethylaminobenzoyl)-3-(4-chlorophenyl)ureaRefChem:126767Clanfenur [INN]N-((4-chlorophenyl)carbamoyl)-2-(dimethylamino)-6-fluorobenzamiden-[(4-chlorophenyl)carbamoyl]-2-(dimethylamino)-6-fluorobenzamideNSC603108MLS002701735Clanfenur (INN)
Show more names
Clanfenur, 10 mM in DMSO3-(4-chlorophenyl)-1-[2-(dimethylamino)-6-fluorobenzoyl]ureaN-[[(4-chlorophenyl)amino]carbonyl]-2-(dimethylamino)-6-fluorobenzamideBenzamide,N-[[(4-chlorophenyl)amino]carbonyl]-2-(dimethylamino)-6-fluoro-
NSC 6031081-(p-Chlorophenyl)-3-(6-fluoro-N,N-dimethylanthraniloyl)ureaN-[(4-chlorophenyl)carbamoyl]-2-(dimethylamino)-6-fluoro-benzamideClanfenurum [Latin]UNII-KAM54NKT1QC16H15ClFN3O2MFCD00868777starbld0009555
Database identifiers
- CAS
51213-99-1
Properties
Computed structural properties
- XLogP
- 3.9
- Topological polar surface area
- 61.4 Ų
- Hydrogen bond donors
- 2
- Hydrogen bond acceptors
- 4
- Rotatable bonds
- 3
- Heavy atoms
- 23
- Formal charge
- 0
- Complexity
- 428
Physicochemical properties
- Density
- 1.371 · 1.371±0.06 g/cm3(Predicted)
- solubility
- 0.1 · Acetonitrile: Slightly soluble: 0.1-1 mg/mLDMSO: Sparingly soluble: 1-10 mg/mL
- pka
- 9.37 · 9.37±0.46(Predicted)
- form
- Solid
- color
- White to off-white
- FDA UNII
- 54 NKT1Q · KAM54NKT1Q
Chemistry & industry
Applications
UsesClanfenur is a substituted benzoylphenylurea, an analogue of the pesticide fenfluramide, with potential antineoplastic activity. Clanfenur can bind to the colchicine-binding site on β-tubulin, inhibit microtubule polymerization, and thus prevent tumor cell replication[1].
Suppliers28 total
陕西缔都医药有限责任公司029-81124775 17791530730 · [email protected]
广州隽沐生物科技股份有限公司020-36607679; 13502246435 · [email protected]
上海毕得医药科技股份有限公司400-1647117 13681763483 · [email protected]
江苏艾康生物医药研发有限公司025-66061636 19370895928 · [email protected]
Advanced chemblocks inc650-6922368 650-6922368;650-6922368 · [email protected]
河南阿尔法化工有限公司0371-55013243 15324716602 · [email protected]
InvivoChem中国13549236410 · [email protected]
上海瀚香生物科技有限公司177-54423994 17754423994 · [email protected]
上海皓鸿生物医药科技有限公司400-8210725 4008210725 · [email protected]
天津普西唐生物医药科技有限公司010-60605840 · [email protected]
BOC Sciences16314854226; +8616314854226 · [email protected]
Related reactions
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Compound notes
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