Basic information
- CAS
55843-86-2- Standard SMILES
CC(C(=O)O)c1ccc(-c2cn3ccccc3n2)cc1- InChIKey
OJGQFYYLKNCIJD-UHFFFAOYSA-N- Molecular formula
- C16H14N2O2
- Average molar mass
- 266.29 g/mol
- Monoisotopic mass
- 266.10552769
Overview
Miroprofen is a monocarboxylic acid that is propionic acid in which one of the hydrogens at position 2 is substituted by a 4-(imidazo[1,2-a]pyridin-2-yl)phenyl group. A non-steroidal anti-inflammatory drug that also exhibits analgesic, antipyretic and platelet aggregation inhibition properties. It has a role as a non-steroidal anti-inflammatory drug, a non-narcotic analgesic, an antipyretic and a platelet aggregation inhibitor. It is a monocarboxylic acid and an imidazopyridine. It is functionally related to a propionic acid.
Names & identifiers
- Preferred name
- Miroprofen
- IUPAC
- 2-(4-imidazo[1,2-a]pyridin-2-ylphenyl)propanoic acid
- English name
- Miroprofen
- Molecular formula
- C16H14N2O2
- Molecular weight
- 266.29
Names & synonyms
Miroprofen55843-86-2MiroprofeneMiroprofenoMiroprofenumY-9213p-Imidazo(1,2-a)pyridin-2-ylhydratropic acidY 9213CHEBI:762492-(p-(2-Imidazo(1,2-a)pyridyl)phenyl)propionic acidS00I5XG4844-Imidazo(1,2-a)pyridin-2-yl-alpha-methylbenzeneacetic acid
Show more names
AntopenOJGQFYYLKNCIJD-UHFFFAOYSA-N2-[p-(Imidazo[1,2-a]pyridin-2-yl)phenyl]propionic acid2-[4-(Imidazo[1,2-a]pyridin-2-yl)phenyl]propionic acid4-Imidazo[1,2-a]pyridin-2-yl-α-methylbenzeneacetic acid
DTXSID30866515Benzeneacetic acid, 4-imidazo(1,2-a)pyridin-2-yl-alpha-methyl-2-[p-(2-imidazo[1,2-a]pyridyl)phenyl]propionic acidRefChem:159055DTXCID90814794Miroprofen [INN]2-(4-imidazo[1,2-a]pyridin-2-ylphenyl)propanoic acid2-[4-(imidazo[1,2-a]pyridin-2-yl)phenyl]propanoic acid
Database identifiers
- CAS
55843-86-2- PubChem CID
- 68752
- DTXSID
DTXSID30866515
Properties
Computed structural properties
- XLogP
- 3.5
- Topological polar surface area
- 54.6 Ų
- Hydrogen bond donors
- 1
- Hydrogen bond acceptors
- 3
- Rotatable bonds
- 3
- Heavy atoms
- 20
- Formal charge
- 0
- Complexity
- 352
Physicochemical properties
- Boiling point
- 409.5 °C · 409.5°C (rough estimate)
- Density
- 1.1262 · 1.1262 (rough estimate)
- refractive index
- 1.624 · 1.6240 (estimate)
- pka
- 3.79 · 3.79±0.10(Predicted)
- FDA UNII
- 0 I5XG484 · S00I5XG484
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
Warning
H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]
P264, P270, P301+P317, P330, and P501 (click each P-code to see the statement)
The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.
Hazard information
Hazard Classes and CategoriesAcute Tox. 4 (100%)
Chemistry & industry
Applications
UsesMiroprofen (Y 0213) is an orally active nonsteroidal anti-inflammatory analgesic (NSAID). Miroprofen exhibits anti-inflammatory, analgesic and anti-platelet activities[1][2][3].
Suppliers4 total
BOC Sciences1-631-485-4226; 16314854226 · [email protected]
TargetMol 中国（陶术生物）400-821-0310 15002144251 · [email protected]
苏州爱玛特生物科技有限公司0512-56316828 400-867-5858;400-867-5858 · [email protected]
上海陶术生物科技股份有限公司+1-781-999-5354 · [email protected]
Additional notes
DefinitionChEBI: A monocarboxylic acid that is propionic acid in which one of the hydrogens at position 2 is substituted by a 4-(imidazo[1,2-a]pyridin-2-yl)phenyl group. A non-steroidal anti-inflammatory drug that also exhibits analgesic, antipyretic and plate et aggregation inhibition properties.
Related reactions
3 records
Compound notes
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