Basic information
- CAS
56355-17-0- Standard SMILES
CC(C(=O)O)c1ccc(Oc2nccs2)cc1- InChIKey
RXZTWBVFHQLTBU-UHFFFAOYSA-N- Molecular formula
- C12H11NO3S
- Average molar mass
- 249.29 g/mol
- Monoisotopic mass
- 249.04596439
Overview
structure given in first source
Names & identifiers
- Preferred name
- Zoliprofen
- IUPAC
- 2-[4-(1,3-thiazol-2-yloxy)phenyl]propanoic acid
- English name
- Zoliprofen
- Molecular formula
- C12H11NO3S
- Molecular weight
- 249.29
Names & synonyms
ZoliprofenZoliprofen [INN]ZoliprofeneZoliprofenoZoliprofene [INN-French]ZoliprofenumZoliprofenum [INN-Latin]Zoliprofeno [INN-Spanish]CCRIS 19282-(4-(2-Thiazolyloxy)phenyl)propionic acidUNII-J2GC047H27BRN 1128230
Show more names
Zoliprofen, 10 mM in DMSOBenzeneacetic acid, α-methyl-4-(2-thiazolyloxy)-
J2GC047H27alpha-Methyl-4-(2-thiazolyloxy)benzeneacetic acidPropionic acid, 2-(p-((2-thiazolyl)oxy)phenyl)-480156-S2-[4-(2-thiazolyloxy)phenyl]propionic acidBenzeneacetic acid, alpha-methyl-4-(2-thiazolyloxy)-Zoliprofene (INN-French)Zoliprofenum (INN-Latin)
Database identifiers
- CAS
56355-17-0- PubChem CID
- 68758
- DTXSID
DTXSID10866553- ChEMBL
CHEMBL2107544- UNII
- J2GC047H27
- Nikkaji
- J23.745K
Properties
Computed structural properties
- XLogP
- 2.8
- Topological polar surface area
- 87.7 Ų
- Hydrogen bond donors
- 1
- Hydrogen bond acceptors
- 5
- Rotatable bonds
- 4
- Heavy atoms
- 17
- Formal charge
- 0
- Complexity
- 266
Physicochemical properties
- FDA UNII
- 2 GC047H27 · J2GC047H27
- Symbol(GHS)
- 7 · GHS07
- Signal word
- Warning
- Hazard statements
- 302 · H302-H315-H319-H335
- Precautionary statements
- 280 · P280-P305+P351+P338
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
Safety data
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- Hazard statements
- H302-H315-H319-H335
- Precautionary statements
- P280-P305+P351+P338
Chemistry & industry
Applications
UsesZoliprofen (480156-S), a new non-steroidal anti-inflammatory agent, has potent pain suppressing effect. Zoliprofen has strong antagonistic action against bradykinin, markedly inhibiting all bradykinin-induced edema and pain reactions. Zoliprofen weakly inhibits Arachidonic acid (HY-109590)-induced edema and pain reactions but also inhibits PGE2 synthesis of bovine vesicular gland microsomes[1].
Upstream & downstream products
Upstream raw materials
Suppliers4 total
銳迪國際科技有限公司18024082417 · [email protected]
上海一飞生物科技有限公司021-65675885 18964387627 · [email protected]
TargetMol中国（陶术生物）15002134094 · [email protected]
上海阿摩尔生物科技有限公司13370042665 18916960931 · [email protected]
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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