(-)-Pindolol
Basic information
- CAS
26328-11-0- Standard SMILES
CC(C)NC[C@H](O)COc1cccc2[nH]ccc12- InChIKey
JZQKKSLKJUAGIC-NSHDSACASA-N- Molecular formula
- C14H20N2O2
- Average molar mass
- 248.32 g/mol
- Monoisotopic mass
- 248.15247789
Overview
(S)-(-)-pindolol is a pindolol. It is an enantiomer of a (R)-(+)-pindolol.
Names & identifiers
- Preferred name
- (-)-Pindolol
- IUPAC
- (2S)-1-(1H-indol-4-yloxy)-3-(propan-2-ylamino)propan-2-ol
- English name
- S(-)-pindolol
- Molecular formula
- C14H20N2O2
- Molecular weight
- 248.32
Names & synonyms
(S)-(-)-pindololl-Pindolol(-)-pindolol(S)-pindololPindolol, (S)-(2S)-1-(1H-indol-4-yloxy)-3-[(propan-2-yl)amino]propan-2-olE34B58KY5WS-PINDOLOL(2S)-1-(1H-indol-4-yloxy)-3-(isopropylamino)propan-2-ol(2S)-1-(1H-indol-4-yloxy)-3-(propan-2-ylamino)propan-2-olUNII-E34B58KY5WCHEBI:48281
Show more names
MT-102AGI-001S(-)-pindolol(-)-PINDOLOL B-ADRENERGIC BLOCKING(S)-1-((1H-indol-4-yl)oxy)-3-(isopropylamino)propan-2-ol(2S)-1-(1H-Indole-4-yloxy)-3-(isopropylamino)propane-2-ol[S,(-)]-1-(1H-Indole-4-yloxy)-3-(isopropylamino)-2-propanol(S)-1-(1H-INDOL-4-YLOXY)-3-[(1-METHYLETHYL)AMINO]-2-PROPANOL(S)-1-(1H-Indole-4-yloxy)-3-[(1-methylethyl)amino]-2-propanol
DTXSID70873364(2S)-1-(1H-indol-4-yloxy)-3-[(1-methylethyl)amino]propan-2-ol2-Propanal, 1-(1H-indol-4-yloxy)-3-((1-methylethyl)amino)-, (S)-2-PROPANOL, 1-(INDOL-4-YLOXY)-3-(ISOPROPYLAMINO)-, (-)-(2S)-1-(1H-INDOL-4-YLOXY)-3-((1-METHYLETHYL)AMINO)-2-PROPANOL2-PROPANOL, 1-(1H-INDOL-4-YLOXY)-3-((1-METHYLETHYL)AMINO)-, (S)-2-Propanol, 1-(1H-indol-4-yloxy)-3-[(1-methylethyl)amino]-, (2S)-2-PROPANOL, 1-(1H-INDOL-4-YLOXY)-3-((1-METHYLETHYL)AMINO)-, (2S)-
Database identifiers
- CAS
26328-11-0- PubChem CID
- 688095
- DTXSID
DTXSID70873364- ChEMBL
CHEMBL117405- ChEBI
CHEBI:48281- UNII
- E34B58KY5W
- Nikkaji
- J221.536E
Properties
Computed structural properties
- XLogP
- 1.8
- Topological polar surface area
- 57.3 Ų
- Hydrogen bond donors
- 3
- Hydrogen bond acceptors
- 3
- Rotatable bonds
- 6
- Heavy atoms
- 18
- Formal charge
- 0
- Complexity
- 248
Experimental & physicochemical properties
DrugsPharmaceuticals -> Listed in ZINC15
Physicochemical properties
- Boiling point
- 457.1 · 457.1±35.0 °C(Predicted)
- Density
- 1.152 · 1.152±0.06 g/cm3(Predicted)
- storage temp.
- 4 °C · Desiccate at +4°C
- solubility
- 0.1 M · 0.1 M NaOH: 0.2 mg/mL
- form
- solid
- pka
- 13.94 · 13.94±0.20(Predicted)
- color
- white
- optical activity
- 23 · [α]23/D 4.38°, c = 1% in methanol(lit.)
- FDA UNII
- 34 B58KY5W · E34B58KY5W
- WGK Germany
- 3 · 3
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
Safety data
- wgk
- 3
Chemistry & industry
Applications
Uses(S)-(-)-Pindolol is a SR-1A/SR-1B antagonist.
Additional notes
DefinitionChEBI: (S)-(-)-pindolol is a pindolol. It is an enantiomer of a (R)-(+)-pindolol.
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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