Delta Sleep-Inducing Peptide
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Basic information
- CAS
62568-57-4- Standard SMILES
C[C@H](NC(=O)[C@H](CC(=O)O)NC(=O)CNC(=O)CNC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCC(=O)O)C(=O)O- InChIKey
ZRZROXNBKJAOKB-GFVHOAGBSA-N- Molecular formula
- C35H48N10O15
- Average molar mass
- 848.8 g/mol
- Monoisotopic mass
- 848.33006086
Overview
A nonapeptide that is found in neurons, peripheral organs, and plasma. This neuropeptide induces mainly delta sleep in mammals. In addition to sleep, the peptide has been observed to affect electrophysiological activity, neurotransmitter levels in the brain, circadian and locomotor patterns, hormonal levels, psychological performance, and the activity of neuropharmacological drugs including their withdrawal.
Names & identifiers
- Preferred name
- Delta Sleep-Inducing Peptide
- IUPAC
- (2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[2-[[(2S)-2-[[(2S)-2-amino-3-(1H-indol-3-yl)propanoyl]amino]propanoyl]amino]acetyl]amino]acetyl]amino]-3-carboxypropanoyl]amino]propanoyl]amino]-3-hydroxypropanoyl]amino]acetyl]amino]pentanedioic acid
- English name
- DELTA SLEEP-INDUCING PEPTIDE
- Molecular formula
- C35H48N10O15
- Molecular weight
- 0
Names & synonyms
Emideltide62568-57-4DSIP nonapeptideEmideltide [INN]DELTA SLEEP-INDUCING PEPTIDEemideltidaDelta sleep-inducing peptide (rabbit)UNII-YN28Z5YZ73YN28Z5YZ73L-Glutamic acid, L-tryptophyl-L-alanylglycylglycyl-L-alpha-aspartyl-L-alanyl-L-serylglycyl-69431-45-4L-Glutamic acid, N-(N-(N-(N-(N-(N-(N-(N-L-tryptophyl-L-alanyl)glycyl)glycyl)-L-alpha-aspartyl)-L-alanyl)-L-seryl)-glycyl)-
Show more names
(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[2-[[(2S)-2-[[(2S)-2-amino-3-(1~{H}-indol-3-yl)propanoyl]amino]propanoyl]amino]acetyl]amino]acetyl]amino]-3-carboxypropanoyl]amino]propanoyl]amino]-3-hydroxypropanoyl]amino]acetyl]amino]pentanedioic acid
Delta Sleep PeptideDelta-Sleep PeptidePeptide, Delta-SleepemideltidumDelta-Sleep-Inducing PeptideDelta-Sleep-Inducing-PeptidePeptide, Delta Sleep-InducingPeptide, Delta-Sleep-Inducing
Properties
Computed structural propertiesFilling in
- XLogP
- -7.1
- Topological polar surface area
- 407 Ų
- Hydrogen bond donors
- 14
- Hydrogen bond acceptors
- 16
- Rotatable bonds
- 25
- Heavy atoms
- 60
- Formal charge
- 0
- Complexity
- 1,610
Physicochemical properties
- FDA UNII
- 28 Z5YZ73 · YN28Z5YZ73
Chemistry & industry
Pharmacology
MeSH Pharmacological Classification
Substances used for their pharmacological actions on any aspect of neurotransmitter systems. Neurotransmitter agents include agonists, antagonists, degradation inhibitors, uptake inhibitors, depleters, precursors, and modulators of receptor function.
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Compound notes
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