Fepradinol
Basic information
- CAS
36981-91-6- Standard SMILES
CC(C)(CO)NCC(O)c1ccccc1- InChIKey
PVOOBRUZWPQOER-UHFFFAOYSA-N- Molecular formula
- C12H19NO2
- Average molar mass
- 209.28 g/mol
- Monoisotopic mass
- 209.14157885
Overview
Fepradinol is an aralkylamine.
Names & identifiers
- Preferred name
- Fepradinol
- IUPAC
- 2-[(2-hydroxy-2-phenylethyl)amino]-2-methylpropan-1-ol
- English name
- Fepradinol
- Molecular formula
- C12H19NO2
- Molecular weight
- 209.287
Names & synonyms
Fepradinol36981-91-6Fepradinolum860MHI4WBARefChem:140229(+-)-alpha-(((2-hydroxy-1,1-dimethylethyl)amino)methyl)benzenemethanolBenzenemethanol, alpha-(((1,1-dimethylethyl)amino)methyl)-2-hydroxy-, (+-)-63075-47-8Fepradinol [INN]2-[(2-hydroxy-2-phenylethyl)amino]-2-methylpropan-1-olDalgen;EL-508G 131
Show more names
DalgenFlexidol
Fepradinol (INN)2-((2-hydroxy-2-phenylethyl)amino)-2-methylpropan-1-ol2-[(2-hydroxy-2-phenyl-ethyl)amino]-2-methyl-propan-1-olFepradinolum [INN-Latin]UNII-860MHI4WBABRN 2094927FEPRADINOL [MI]alpha-(((1,1-Dimethyl-2-hydroxyethyl)amino)methyl)benzyl alcohol
Database identifiers
- CAS
36981-91-6、63075-47-8- PubChem CID
- 68819
- ChEMBL
CHEMBL2106269- ChEBI
CHEBI:134878- UNII
- 860MHI4WBA
- Nikkaji
- J324.195E
Properties
Computed structural properties
- XLogP
- 0.6
- Topological polar surface area
- 52.5 Ų
- Hydrogen bond donors
- 3
- Hydrogen bond acceptors
- 3
- Rotatable bonds
- 5
- Heavy atoms
- 15
- Formal charge
- 0
- Complexity
- 176
Physicochemical properties
- Melting point
- 142 · 142-143°; mp 140-142° (Staibano); mp 139° (Biekert)
- storage temp.
- -20 °C · Hygroscopic, -20°C Freezer, Under inert atmosphere
- solubility
- Ethyl Acetate (Slightly), Methanol (Slightly)
- form
- Solid
- color
- White to Off-White
- FDA UNII
- 860 MHI4WBA · 860MHI4WBA
Chemistry & industry
Pharmacology
MeSH Pharmacological Classification
Anti-inflammatory agents that are non-steroidal in nature. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects.
Applications
UsesFepradinol is a non-steroidal anti-inflammatory drug (NSAID).
Additional notes
DefinitionChEBI: Fepradinol is an aralkylamine.
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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