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H-Glu(amc)-OH

HCID 688485
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Basic information

CAS
72669-53-5
Standard SMILES
Cc1cc(=O)oc2cc(NC(=O)CC[C@H](N)C(=O)O)ccc12
InChIKey
JPOAPPISZAGCAO-NSHDSACASA-N
Molecular formula
C15H16N2O5
Average molar mass
304.3 g/mol
Monoisotopic mass
304.10592162

Names & identifiers

Preferred name
H-Glu(amc)-OH
IUPAC
(2S)-2-amino-5-[(4-methyl-2-oxochromen-7-yl)amino]-5-oxopentanoic acid
English name
H-Glu(amc)-OH
Molecular formula
C15H16N2O5
Molecular weight
304.3

Names & synonyms

H-GLU(AMC)-OH72669-53-5L-Glutamic acid gamma-(7-amido-4-methylcoumarin)gamma-l-glutamic acid 7-amido-4-methylcoumarinMFCD00038085SCHEMBL57489AKOS026674350FD21475AS-49086(S)-2-Amino-5-((4-methyl-2-oxo-2H-chromen-7-yl)amino)-5-oxopentanoic acid(S)-2-Amino-5-[(4-methyl-2-oxo-2H-chromen-7-yl)amino]-5-oxopentanoic Acid(2S)-2-amino-5-[(4-methyl-2-oxochromen-7-yl)amino]-5-oxopentanoic acid
Show more names
L-Glu(AMC)-OHH-L-Glu(AMC)-OHGLUTAMIC ACID(AMC)-OHH-GLU(AMC)-OH USP/EP/BPGAMMA-L-GLUTAMIC ACID-AMC7-(gamma-glutamyl)-4-methylcoumarylamideγ-L-Glutamic acid 7-amido-4-methylcoumarinL-Glutamic acid 5-(7-amido-4-methylcoumarin)
G-L-Glutamic acid 7-amido-4-methylcoumarin(2S)-2-Amino-5-[(4-methyl-2-oxo-chromen-7-yl)amino]-5-oxo-pentanoic acid(S)-2-Amino-5-((4-mJPOAPPISZAGCAO-NSHDSACASA-NDTXSID901379667EG31007SY291390HY-137416

Database identifiers

CAS
72669-53-5
PubChem CID
688485
DTXSID
DTXSID901379667
Nikkaji
J557.344K

Properties

Computed structural properties

XLogP
-1.9
Topological polar surface area
119 Ų
Hydrogen bond donors
3
Hydrogen bond acceptors
6
Rotatable bonds
5
Heavy atoms
22
Formal charge
0
Complexity
502

Physicochemical properties

Melting point
190 · 190-196 °C (dec.)
Boiling point
698 °C · 698°C at 760 mmHg
Density
1.406 g/cm3 · 1.406 g/cm3
storage temp.
20 °C · −20°C
form
Powder
pka
2.211 · 2.211±0.10(predicted)
color
White to Off-white
Appearance
White to off-white powder
CAS DataBase Reference
72669 · 72669-53-5
Symbol(GHS)
7 · GHS07
Signal word
Warning
Hazard statements
302 · H302-H315-H319-H335
Precautionary statements
280 · P280-P305+P351+P338
Safety Statements
24 · 24/25
WGK Germany
3 · 3
HS Code
29400000 · 29400000

Safety & regulation

Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.

Safety data

wgk
3
hs_code
29400000
Signal word
Warning
Symbol(GHS)
GHS07
safety_code
24/25
Hazard statements
H302-H315-H319-H335
Precautionary statements
P280-P305+P351+P338

Chemistry & industry

Applications · 3 items

DescriptionL-Glutamic acid γ-(7-amido-4-methylcoumarin) is a substrate for aminopeptidase or the assay of γ-glutamyl transferase producing a blue fluorescent solution upon cleavage.

UsesFluorogenic substrate for g-Glutamyl transferase.

UsesA substrate for aminopeptidase a or the assay of gamma-glutamyl transferase producing a blue fluorescent solution upon cleavage

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