Basic information
- CAS
70312-00-4- Standard SMILES
Cc1ccccc1N1CCN(C2CCc3cc(O)ccc3C2)CC1- InChIKey
ZYGBSDBJSDMKLV-UHFFFAOYSA-N- Molecular formula
- C21H26N2O
- Average molar mass
- 322.4 g/mol
- Monoisotopic mass
- 322.20451346
Overview
impairs gastric relaxation
Names & identifiers
- Preferred name
- BK 34-530
- IUPAC
- 6-[4-(2-methylphenyl)piperazin-1-yl]-5,6,7,8-tetrahydronaphthalen-2-ol
- English name
- Tolnapersine
- Molecular formula
- C21H26N2O
- Molecular weight
- 322.44
Names & synonyms
BK 34-5302-Naphthalenol, 5,6,7,8-tetrahydro-6-(4-(2-methylphenyl)-1-piperazinyl)-RefChem:190297Tolnapersine70312-00-4TolnapersinaTolnapersine [INN]6-[4-(2-methylphenyl)piperazin-1-yl]-5,6,7,8-tetrahydronaphthalen-2-ol72MZZ4V9KLNSC-757872BK 34/530Tolnapersinum
Show more names
Tolnapersine ISO 9001：2015 REACH6-[4-(2-Methylphenyl)-1-piperazinyl]-5,6,7,8-tetrahydro-2-naphthol6-(4-(2-Methylphenyl)-1-piperazinyl)-5,6,7,8-tetrahydronaphthalen-2-ol2-Naphthalenol, 5,6,7,8-tetrahydro-6-[4-(2-methylphenyl)-1-piperazinyl]-
5,6,7,8-Tetrahydro-6-(4-o-tolyl-1-piperazinyl)-2-naphthol5,6,7,8-tetrahydro-6-(4-(2-methylphenyl)-1-piperazinyl)naphthalen-2-olTolnapersinum [Latin]Tolnapersina [Spanish]UNII-72MZZ4V9KLorb1745199SCHEMBL2109217CHEMBL2105564
Database identifiers
- CAS
70312-00-4- PubChem CID
- 68893
Properties
Computed structural properties
- XLogP
- 4.3
- Topological polar surface area
- 26.7 Ų
- Hydrogen bond donors
- 1
- Hydrogen bond acceptors
- 3
- Rotatable bonds
- 2
- Heavy atoms
- 24
- Formal charge
- 0
- Complexity
- 407
Physicochemical properties
- FDA UNII
- 72 MZZ4V9KL · 72MZZ4V9KL
Chemistry & industry
Applications
UsesTolnapersine exhibits multidrug resistance (MDR) reversal activity, which reverses the resistance of tumor cells to multiple chemotherapy drugs by affecting P-glycoprotein (Pgp) on the cell membrane[1].
Suppliers6 total
陕西缔都化学有限公司029-029-81123119 17391733320 · [email protected]
上海陶术生物科技股份有限公司13564774135 · [email protected]
career henan chemical co+86-0371-86658258 · [email protected]
TargetMol中国（陶术生物）4008200310 15002144251 · [email protected]
重庆卡兰医药有限公司[email protected]
Dideu Industries Group Limited+86-29-81148696 +86-15129568250 · [email protected]
Related reactions
2 records
Compound notes
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