Basic information
- CAS
73445-46-2- Standard SMILES
COc1ccc(-c2nc(-c3ccc(F)cc3F)[nH]c2-c2ccc(OC)cc2)cc1- InChIKey
ITFWPRPSIAYKMV-UHFFFAOYSA-N- Molecular formula
- C23H18F2N2O2
- Average molar mass
- 392.4 g/mol
- Monoisotopic mass
- 392.13363415
Overview
Fenflumizole is a small molecule drug. Fenflumizole has a monoisotopic molecular weight of 392.13 Da.
Names & identifiers
- Preferred name
- Fenflumizole
- IUPAC
- 2-(2,4-difluorophenyl)-4,5-bis(4-methoxyphenyl)-1H-imidazole
- English name
- Fenflumizole
- Molecular formula
- C23H18F2N2O2
- Molecular weight
- 392.4
Names & synonyms
FenflumizoleFenflumizol73445-46-2FenflumizolumDTXSID70223668PD0931191QRefChem:140153DTXCID001461592-(2,4-difluorophenyl)-4,5-bis(4-methoxyphenyl)-1H-imidazoleFenflumizol [INN]2-(2,4-Difluorophenyl)-4,5-bis(p-methoxyphenyl)imidazoleFenflumizole [INN]
Show more names
1H-Imidazole, 2-(2,4-difluorophenyl)-4,5-bis(4-methoxyphenyl)-
Fenflumizole [INN-French]Fenflumizolum [INN-Latin]BRN 4766971UNII-PD0931191Q4,5-Bis(4-methoxyphenyl)-2-(2,4-difluorophenyl)-1H-imidazoleFENFLUMIZOLE [WHO-DD]SCHEMBL286890CHEMBL447187
Database identifiers
- CAS
73445-46-2- PubChem CID
- 68917
- DTXSID
DTXSID70223668- ChEMBL
CHEMBL447187- UNII
- PD0931191Q
- Nikkaji
- J227.850B
Properties
Computed structural properties
- XLogP
- 5.2
- Topological polar surface area
- 47.1 Ų
- Hydrogen bond donors
- 1
- Hydrogen bond acceptors
- 5
- Rotatable bonds
- 5
- Heavy atoms
- 29
- Formal charge
- 0
- Complexity
- 509
Physicochemical properties
- Boiling point
- 555.2 · 555.2±50.0 °C(Predicted)
- Density
- 1.252 · 1.252±0.06 g/cm3(Predicted)
- pka
- 11.25 · 11.25±0.12(Predicted)
- FDA UNII
- 931191 Q · PD0931191Q
Chemistry & industry
Pharmacology
MeSH Pharmacological Classification
Anti-inflammatory agents that are non-steroidal in nature. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects.
Suppliers2 total
Lanospharma Laboratories Co.,Ltd13440048448 · [email protected]
Spectrum Chemical Mfg. Corp.[email protected]
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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