Basic information
- CAS
593-88-4- Standard SMILES
C[As](C)C- InChIKey
HTDIUWINAKAPER-UHFFFAOYSA-N- Molecular formula
- C3H9As
- Average molar mass
- 120.03 g/mol
- Monoisotopic mass
- 119.99202
Overview
Trimethylarsine is an arsine that is arsane in which each of the hydrogens is substituted by a methyl group. It derives from a hydride of an arsane.
Names & identifiers
- Preferred name
- Trimethylarsine
- IUPAC
- trimethylarsane
- English name
- TRIMETHYLARSINE
- Molecular formula
- C3H9As
- Molecular weight
- 120.03
Names & synonyms
Trimethylarsinetrimethylarsane593-88-4TrimethylarsenicArsine, trimethyl-AsMe3(CH3)3AsMQ83UQ8A1QDTXSID4073203trimethylarsane;trimethylarsenicCHEBI:27130RefChem:191775
Show more names
trimethyl-arsinarsine,trimethyl-Trimethylarsine,99%TrimethylarsineelecgrcolorlessliqTRIMETHYLARSINE 99.999% METAL PURITYTrimethylarsine,elec.gr.(99.995%-As)PURATREM
DTXCID1042603209-815-8C3H9AsMFCD00014838Trimethylarsine, elec. gr.4-04-00-03665 (Beilstein Handbook Reference)EINECS 209-815-8UNII-MQ83UQ8A1Q
Database identifiers
- CAS
593-88-4- PubChem CID
- 68978
- DTXSID
DTXSID4073203- ChEBI
CHEBI:27130- UNII
- MQ83UQ8A1Q
- EC Number
- 209-815-8
- Nikkaji
- J459F
Properties
Computed structural properties
- Topological polar surface area
- 0 Ų
- Hydrogen bond donors
- 0
- Hydrogen bond acceptors
- 0
- Rotatable bonds
- 0
- Heavy atoms
- 4
- Formal charge
- 0
- Complexity
- 8
Experimental & physicochemical properties
Chemical ClassesMetals -> Arsenic Compounds, Organic
Physical DescriptionColorless liquid; [Sigma-Aldrich MSDS]
Physicochemical properties
- Melting point
- -87 · -87,3°C
- Boiling point
- 51 °C · 51°C
- Density
- 1 · 1,124 g/cm3
- Flash point
- -25 °C · -25°C
- storage temp.
- Refrigerator, under inert atmosphere
- solubility
- Benzene
- form
- liquid
- color
- colorless
- Specific Gravity
- 1.124 · 1.124
- Sensitive
- air sensitive
- Stability
- Volatile
- REACH Annex XVII Substances List
- Trimethylarsine (593-88-4)
- FDA UNII
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
Danger
H225 (41.5%): Highly Flammable liquid and vapor [Danger Flammable liquids]
P210, P223, P231+P232, P233, P240, P241, P242, P243, P261, P264, P264+P265, P270, P271, P273, P280, P301+P316, P302+P335+P334, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P316, P319, P321, P330, P332+P317, P337+P317, P362+P364, P370+P378, P391, P402+P404, P403+P233, P403+P235, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 94 reports by companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Hazard information
Regulatory Information
PMN - indicates a commenced PMN (Pre-Manufacture Notices) substance.
Restricted substance: Trimethylarsine
Hazards SummaryCauses somnolence, tremor, and ataxia in inhalation lethal-concentration studies of mice; [RTECS] May cause irritation; [Sigma-Aldrich MSDS] See Triphenylarsine, Diethylarsine, and tert-Butylarsine.
Hazard Classes and CategoriesFlam. Liq. 2 (41.5%)
Safety & protection
Minimum Risk LevelAcute Oral: 0.005 mg/kg/day (L134)
Chronic Oral: 0.0003 mg/kg/day (L134)
Chronic Inhalation: 0.01 mg/m3 (L134)
Permissible Exposure Limit (PEL)0.5 [mg/m3], as As
Toxicology
Chemistry & industry
Pharmacology
Metabolism/Metabolites
Arsenic is absorbed mainly by inhalation or ingestion, as to a lesser extent, dermal exposure. It is then distributed throughout the body, where it is reduced into arsenite if necessary, then methylated into monomethylarsenic (MMA) and dimethylarsenic acid (DMA) by arsenite methyltransferase. Arsenic and its metabolites are primarily excreted in the urine. Arsenic is known to induce the metal-binding protein metallothionein, which decreases the toxic effects of arsenic and other metals by binding them and making them biologically inactive, as well as acting as an antioxidant. (L20)
Uses & manufacturing
UsesTrimethylarsine is used in the microelectronics industry, the production of other organoarsenic compounds, and as a ligand in coordination chemistry. (L388)
General Manufacturing InformationArsine, trimethyl-: ACTIVE
Applications
UsesTrimethylarsine is an environmental pollutant found in lake sediment. Trimethylarsine is toxic to mammalian cells.
Suppliers9 total
上海源象化学有限公司17312431727 · [email protected]
Aladdin Scientific[email protected]
上海迈瑞尔生化科技有限公司4006356688 18621169109 · [email protected]
上海阿拉丁生化科技股份有限公司6206333 13167063860 · [email protected]
陕西缔都医药化工有限公司
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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