Basic information
- CAS
599-71-3- Standard SMILES
O=S(=O)(NO)c1ccccc1- InChIKey
BRMDATNYMUMZLN-UHFFFAOYSA-N- Molecular formula
- C6H7NO3S
- Average molar mass
- 173.19 g/mol
- Monoisotopic mass
- 173.01466408
Overview
Piloty's Acid is a sulfonamide.
Names & identifiers
- Preferred name
- N-Hydroxybenzenesulfonamide
- IUPAC
- N-hydroxybenzenesulfonamide
- English name
- BENZENESULFOHYDROXAMIC ACID
- Molecular formula
- C6H7NO3S
- Molecular weight
- 173.19
Names & synonyms
N-Hydroxybenzenesulfonamide599-71-3Piloty's acidBenzenesulfohydroxamic acidBenzenesulfonamide, N-hydroxy-N-(Phenylsulfonyl)hydroxylamineBenzsulfohydroxamic acidHydroxylamine, N-(phenylsulfonyl)-C64L4UMH19NSC-45357DTXSID4060521RefChem:174258
Show more names
Piloty’Piloty's Acidbenzsulfohydroxamicacidbenzsulfo-hydroxamicaciN-HYDROXYBENZENSUFONAMIDEBENZENESULFHYDROXAMIC ACIDn-hydroxy-benzenesulfonamid
DTXCID2042725209-973-8Hydroxamic acid, benzsulfo-piloty acidMFCD00025013CHEMBL55310Benzenesulphonohydroxamic acidEINECS 209-973-8
Database identifiers
- CAS
599-71-3- PubChem CID
- 69033
- DTXSID
DTXSID4060521- ChEMBL
CHEMBL55310- ChEBI
CHEBI:185767
Properties
Computed structural properties
- XLogP
- 0.5
- Topological polar surface area
- 74.8 Ų
- Hydrogen bond donors
- 2
- Hydrogen bond acceptors
- 4
- Rotatable bonds
- 2
- Heavy atoms
- 11
- Formal charge
- 0
- Complexity
- 200
Experimental & physicochemical properties
Chemical ClassesNitrogen Compounds -> Other Aromatics (Nitrogen)
LogP0.48
Vapor Pressure0.00000132 [mmHg]
Physical DescriptionSolid; [Merck Index] White crystals; [Acros Organics MSDS]
Physicochemical properties
- Melting point
- 122 · 122-125 °C
- Boiling point
- 351.5 · 351.5±25.0 °C(Predicted)
- Density
- 1.342 · 1.342 (estimate)
- refractive index
- 1.55 · 1.5500 (estimate)
- storage temp.
- 2 · 2-8°C
- solubility
- 30 mg/ml; · DMF: 30 mg/ml; DMSO: 20 mg/ml; Ethanol: 30 mg/ml; PBS (pH7.2): 2 mg/ml
- pka
- 9.29 · 9.29(at 25℃)
- form
- solid
- color
- White to off-white
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
Warning
H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 2 reports by companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Hazard information
Hazards SummaryOral lethal-dose (rat) >500 mg/kg; [RTECS] An irritant; [Acros Organics MSDS]
Hazard Classes and CategoriesSkin Irrit. 2 (100%)
Safety data
- wgk
- 3
- tsca
- TSCA listed
- rtecs
- MX9350000
- hs_code
- 29350090
- Toxicity
- LD orl-rat: >500 mg/kg NCNSA6 5,42,53
- risk_code
- 36/37/38
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- hazard_code
- Xi
- safety_code
- 22-24/25
- Hazard statements
- H302-H315-H319-H335
- Precautionary statements
- P261-P280-P301+P312-P302+P352-P305+P351+P338
Chemistry & industry
Uses & manufacturing
Uses
Used in biochemical model studies and in the Angeli-Rimimi test for aldehydes; [Merck Index] Piloty's Acid is one of the most commonly used nitroxyl (HNO) donors, decomposing to form HNO and benzenesulfinate anion under basic conditions. [Santa Cruz Biotechnology]
General Manufacturing InformationBenzenesulfonamide, N-hydroxy-: INACTIVE
Applications
UsesBenzenesulfohydroxamic Acid can be used as HNO/NO- donor in biochemical model studies, In the Angeli-Rimini test for aldehydes.
Suppliers48 total
陕西凯尔凯医药科技有限公司029-2148545164 17392779578 · [email protected]
梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
Career Henan Chemica Co+86-0371-86658258 +86-13203830695 · [email protected]
上海麦克林生化科技股份有限公司021-50706066 15221275939 · [email protected]
武汉欣扬瑞和化学科技有限公司153-07155313 15307155313 · [email protected]
焦作沃恩生物科技有限责任公司0391-3702345 18739121806 · [email protected]
Dayang Chem (Hangzhou) Co.,Ltd.+86-0571-88938639 17705817739 · [email protected]
Related reactions
10 records
Compound notes
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