Clofilium Phosphate
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Basic information
- CAS
68379-03-3- Standard SMILES
CCCCCCC[N+](CC)(CC)CCCCc1ccc(Cl)cc1.O=P([O-])(O)O- InChIKey
HBLQZEWZVJXHKQ-UHFFFAOYSA-M- Molecular formula
- C21H39ClNO4P
- Average molar mass
- 436 g/mol
- Monoisotopic mass
- 435.2305234
Overview
See also: Clofilium (has active moiety).
Names & identifiers
- Preferred name
- Clofilium Phosphate
- IUPAC
- 4-(4-chlorophenyl)butyl-diethyl-heptylazanium;dihydrogen phosphate
- English name
- Clofilium phosphate
- Molecular formula
- C63H111Cl3N3O4P
- Molecular weight
- 1111.905901
Names & synonyms
CLOFILIUM PHOSPHATE68379-03-3Fosfato de clofilioPhosphate de clofiliumClofilii phosphasLY 150378O1IXD77P8SLY-150378Benzenebutanaminium, 4-chloro-N,N-diethyl-N-heptyl-, phosphate (1:1)RefChem:918833clofilium phosphate (1:1)Clofilium (phosphate)
Show more names
ClofiliumClofilium phosphate ISO 9001：2015 REACHN,N-Diethyl-N-heptyl-4-chlorobenzenebutan-1-aminium
4-(4-chlorophenyl)butyl-diethyl-heptylazanium;dihydrogen phosphate(4-(p-Chlorophenyl)butyl)diethylheptylammonium phosphate (1:1)UNII-O1IXD77P8SClofilii phosphas [INN-Latin]Clofilium phosphate [USAN:INN]Fosfato de clofilio [INN-Spanish]Phosphate de clofilium [INN-French]D03547
Database identifiers
- CAS
68379-03-3- PubChem CID
- 6917809
- DTXSID
DTXSID60987924- ChEMBL
CHEMBL32510- UNII
- O1IXD77P8S
Properties
Computed structural propertiesFilling in
- Topological polar surface area
- 80.6 Ų
- Hydrogen bond donors
- 2
- Hydrogen bond acceptors
- 4
- Rotatable bonds
- 13
- Heavy atoms
- 28
- Formal charge
- 0
- Complexity
- 317
Physicochemical properties
- FDA UNII
- 1 IXD77P8S · O1IXD77P8S
Chemistry & industry
Pharmacology
MeSH Pharmacological Classification
Agents used for the treatment or prevention of cardiac arrhythmias. They may affect the polarization-repolarization phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibers. Anti-arrhythmia agents are often classed into four main groups according to their mechanism of action: sodium channel blockade, beta-adrenergic blockade, repolarization prolongation, or calcium channel blockade.
A class of drugs that act by inhibition of potassium efflux through cell membranes. Blockade of potassium channels prolongs the duration of ACTION POTENTIALS. They are used as ANTI-ARRHYTHMIA AGENTS and VASODILATOR AGENTS.
Applications
UsesCardiac depressant (antiarrhythmic).
Related reactions
0 records
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Compound notes
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