Basic information
- CAS
676-96-0- Standard SMILES
CP(C)(C)=O- InChIKey
LRMLWYXJORUTBG-UHFFFAOYSA-N- Molecular formula
- C3H9OP
- Average molar mass
- 92.08 g/mol
- Monoisotopic mass
- 92.0391019
Overview
structure in first source
Names & identifiers
- Preferred name
- Trimethylphosphine oxide
- IUPAC
- dimethylphosphorylmethane
- English name
- Trimethylphosphine oxide
- Molecular formula
- C3H9OP
- Molecular weight
- 92.08
Names & synonyms
Trimethylphosphine oxide676-96-04M39GK79DVDTXSID90217923RefChem:191805DTXCID40140414211-633-9trimethylphosphineoxidedimethylphosphorylmethanePhosphine oxide, trimethyl-(DIMETHYLPHOSPHORYL)METHANE(CH3)3PO
Show more names
TrimethylphosphinoxidOseltamivir Impurity 178(Dimethyl-phosphinoyl)-methanedimethylphosphoryl)methane ,>97%Trimethylphosphine oxide/676-96-0Phosphine oxide,trimethyl- (6CI,8CI,9CI)
Me3POMFCD00013910UNII-4M39GK79DVPhosphine oxide, trimethyl- (6CI,8CI,9CI)SY061294CS-0107712F20530C3H9OP
Database identifiers
- CAS
676-96-0- PubChem CID
- 69609
- DTXSID
DTXSID90217923- ChEMBL
CHEMBL5189319- UNII
- 4M39GK79DV
- EC Number
- 211-633-9
- Nikkaji
- J1.191.948K、J536C
Properties
Computed structural properties
- XLogP
- -0.6
- Topological polar surface area
- 17.1 Ų
- Hydrogen bond donors
- 0
- Hydrogen bond acceptors
- 1
- Rotatable bonds
- 0
- Heavy atoms
- 5
- Formal charge
- 0
- Complexity
- 53
Experimental & physicochemical properties
SpringerMaterials Properties31P nuclear magnetic resonance spectrum
Physicochemical properties
- Melting point
- 140 · 140-141°C
- Boiling point
- 194 ℃ · 194℃
- Density
- 0.9 · 0.900
- Flash point
- 71 ℃ · 71℃
- storage temp.
- 2 · under inert gas (nitrogen or Argon) at 2-8°C
- solubility
- Soluble in polar organic solvents.
- form
- Crystalline
- Appearance
- White to light yellow Solid
- FDA UNII
- 4 M39GK79DV · 4M39GK79DV
- Symbol(GHS)
- 7 · GHS07
- Signal word
- Warning
- Hazard statements
- 302 · H302-H315-H319-H335
- Precautionary statements
- 261 · P261-P280a-P304+P340-P305+P351+P338-P405-P501a
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
Warning
H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]
P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 4 reports by companies from 1 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Safety data
- hs_code
- 29319090
- risk_code
- 22-36/37/38
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- safety_code
- 26-36
- Hazard statements
- H302-H315-H319-H335
- Precautionary statements
- P261-P280a-P304+P340-P305+P351+P338-P405-P501a
Chemistry & industry
Applications
UsesTrimethylphosphine oxide is a common side product in organic synthesis, including the Wittig, Staudinger, Mitsunobu reactions and also in the manufacture of triphenylphosphine. It is a popular reagent to induce the crystallization of various chemical compounds. It acts as an excellent ligand for hard metal centers. It can react with 9-methyl-9-azonianthracene methyl sulfate to get (10-methyl-9,10-dihydro-acridin-9-yl)-phosphonic acid dimethyl ester using sodium iodide and acetonitrile as solvent.
Upstream & downstream products
Upstream raw materials
Downstream products
Suppliers76 total
湖北永阔科技有限公司027-59223108 15972152991 · [email protected]
Hebei Chuanghai Biotechnology Co., Ltd+86-17732866630 · [email protected]
毕佳索（上海毕得医药科技股份有限公司）400-6005915 · [email protected]
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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