Basic information
- Standard SMILES
O=C(O)c1cc(C(=O)O)c(C(=O)O)cc1C(=O)O- InChIKey
CYIDZMCFTVVTJO-UHFFFAOYSA-N- Molecular formula
- C10H6O8
- Average molar mass
- 254.15 g/mol
- Monoisotopic mass
- 254.00626715
Overview
Pyromellitic acid is a tetracarboxylic acid that is benzene substituted by four carboxy groups at positions 1, 2, 4 and 5 respectively. It is a member of benzoic acids and a tetracarboxylic acid.
Names & identifiers
- Preferred name
- Pyromellitic Acid
- IUPAC
- benzene-1,2,4,5-tetracarboxylic acid
- English name
- Pyromellitic acid
- Molecular formula
- C10H6O8
- Molecular weight
- 254.15
Names & synonyms
PYROMELLITIC ACID89-05-4Benzene-1,2,4,5-tetracarboxylic acid1,2,4,5-Benzenetetracarboxylic acidDTXSID8044466D9UXG2U6ZUNSC-6369DTXCID6024466CHEBI:45165RefChem:177858201-879-5USAF XR-20
Show more names
1,2,4,5-BenzenetetracarboxyL1,2,4,5-Benzenetetracarboxylic acid, 96% 5GRusafxr-20AKOS AUF2102pyromelliticaciPyrome1htic Acid
1,2,4,5-TetracarboxybenzeneMFCD000024711,2,4,5-Benzene-tetracarboxylic acidBRN 18876591,4,5-TetracarboxybenzeneNSC6369EC 201-879-5BDBM512625
Database identifiers
- CAS
89-05-4- PubChem CID
- 6961
- DTXSID
DTXSID8044466- ChEMBL
CHEMBL1235346- ChEBI
CHEBI:45165- UNII
- D9UXG2U6ZU
- EC Number
- 201-879-5
- Nikkaji
- J4.299D
Properties
Computed structural properties
- XLogP
- 0
- Topological polar surface area
- 149 Ų
- Hydrogen bond donors
- 4
- Hydrogen bond acceptors
- 8
- Rotatable bonds
- 4
- Heavy atoms
- 18
- Formal charge
- 0
- Complexity
- 327
Experimental & physicochemical properties
Chemical ClassesOther Classes -> Organic Acids
DrugsPharmaceuticals -> Listed in ZINC15
SpringerMaterials Properties13C nuclear magnetic resonance spectrum
Density1.79 @25 °C
Food Contact SubstancesFCS -> FDA Cumulative Estimated Daily Intake (CEDI)
Physical DescriptionPowder; [Alfa Aesar MSDS]
Dissociation Constants1.87 (at 25 °C)
Physicochemical properties
- Melting point
- 281 · 281-284.5 °C(lit.)
- Boiling point
- 317.36 °C · 317.36°C (rough estimate)
- Density
- 0 · 0,56 g/cm3
- refractive index
- 1.701 · 1.7010 (estimate)
- Flash point
- 325 °C · 325 °C
- storage temp.
- 30 °C · Store below +30°C.
- solubility
- 0.1 M · 0.1 M NaOH: 0.2 M, clear, faintly yellow
- pka
- 1 · pK1: 1.92;pK2: 2.87;pK3: 4.49;pK4: 5.63 (25°C)
- form
- Crystalline Powder
- color
- White to very slightly yellow
- Water Solubility
- 1.5 g/100 · 1.5 g/100 mL (20 ºC)
- Merck
- 14 · 14,8004
- Henry's Law Constant
- 1.6 · 1.6×1013 mol/(m3Pa) at 25℃, Yaws (2003)
- Stability
- Stable. Incompatible with strong oxidizing agents, strong bases.
- InChI
- 1S/C10H6O8/c11-7(12)3-1-4(8(13)14)6(10(17)18)2-5(3)9(15)16/h1-2H,(H,11,12)(H,13,14)(H,15,16)(H,17,18)
- InChIKey
- CYIDZMCFTVVTJO-UHFFFAOYSA-N
- SMILES
- OC(=O)c1cc(C(O)=O)c(cc1C(O)=O)C(O)=O
- LogP
- 0.15 at · 0.15 at 25℃
- CAS DataBase Reference
- 89 · 89-05-4(CAS DataBase Reference)
- EWG's Food Scores
- 1 · 1
- FDA UNII
- 9 UXG2U6ZU · D9UXG2U6ZU
- NIST Chemistry Reference
- 1 · 1,2,4,5-Benzene-tetracarboxylic acid(89-05-4)
- EPA Substance Registry System
- 1 · 1,2,4,5-Benzenetetracarboxylic acid (89-05-4)
- UNSPSC Code
- 12352106 · 12352106
- NACRES
- 22 · NA.22
- Symbol(GHS)
- 7 · GHS07
- Signal word
- Warning
- Hazard statements
- 319 · H319
- Precautionary statements
- 280 · P280-P305+P351+P338-P337+P313
- PPE
- 95 · dust mask type N95 (US), Eyeshields, Gloves
- Hazard Codes
- Xi
- Risk Statements
- 36 · 36/37/38-36
- Safety Statements
- 26 · 26-36-37/39-24/25
- WGK Germany
- 3 · 3
- RTECS
- 9275000 · DB9275000
- F
- 34 · 34
- TSCA
- TSCA listed
- HS Code
- 29173980 · 29173980
- Storage Class
- 11 · 11 - Combustible Solids
- REACH Registrations
- Inactive
Safety & regulation
GHS classification
GHS Classification
This chemical does not meet GHS hazard criteria for 53.3% (128 of 240) of all reports.
Warning
H315 (21.2%): Causes skin irritation [Warning Skin corrosion/irritation]
P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 240 reports by companies from 11 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Not Classified
Hazard information
Regulatory Information
Chemical: 1,2,4,5-Benzenetetracarboxylic acid
Status: Cease Manufacture Update: 28-03-2012 https://echa.europa.eu/registration-dossier/-/registered-dossier/12839
1,2,4,5-Benzenetetracarboxylic acid: Does not have an individual approval but may be used under an appropriate group standard
Hazards SummaryIntraperitoneal LD50 (mouse) = 300 mg/kg; [RTECS] A skin and strong eye irritant; [Alfa Aesar MSDS]
Hazard Classes and CategoriesSkin Irrit. 2 (21.2%)
Safety & protection
Protective Action Criteria (PAC)
0.98 [mg/m3]
11 [mg/m3]
65 [mg/m3]
Safety data
- F
- 34
- PPE
- dust mask type N95 (US), Eyeshields, Gloves
- wgk
- 3
- tsca
- TSCA listed
- rtecs
- DB9275000
- hs_code
- 29173980
- risk_code
- 36/37/38-36
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- hazard_code
- Xi
- safety_code
- 26-36-37/39-24/25
- Storage Class
- 11 - Combustible Solids
- Hazard statements
- H319
- REACH Registrations
- Inactive
- Precautionary statements
- P280-P305+P351+P338-P337+P313
Chemistry & industry
Uses & manufacturing
Uses
Used as a metal powder coating additive; [ExPub: ECHA REACH Registrations]
Painting (Pigments, Binders, and Biocides) [Category: Paint]
General Manufacturing Information1,2,4,5-Benzenetetracarboxylic acid: ACTIVE
Applications
UsesPyromellitic acid is an eluent used in anion chromatography and forms complexes with magnesium and calcium ions. It is used as a curing agent, as an intermediate for powder coating and a cross-linking agent for alkyd resin. It is involved in the synthesis of polyimide and pyromellitic octyl.
UsesPyromellitic acid (PMA) is mainly used as intermediate for powder coating. Product Data Sheet
Uses1,2,4,5-benzenetetracarboxylic acid is used for the synthesis of the polyimide, pyromellitic octyl, etc., it is the main raw material of matting curing agent.
Upstream & downstream products
Upstream raw materials
Downstream products
Suppliers50 total
国药集团化学试剂有限公司86-21-63210123 · [email protected]
梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
武汉欣扬瑞和化学科技有限公司153-07155313 15307155313 · [email protected]
T&W GROUP021-61551611 13296011611 · [email protected]
爱斯特（成都）生物制药股份有限公司+86-28-85122536 85324413 · [email protected]
Baoji Guokang Healthchem co.,ltd+8615604608665 15604608665 · [email protected]
Dayang Chem (Hangzhou) Co.,Ltd.+86-0571-88938639 17705817739 · [email protected]
Hebei Yanxi Chemical Co., Ltd.+86-17531190177 · [email protected]
北京安司莫森技术有限公司010-82954736 13391601435 · [email protected]
科瑞迪化学400-821-5857 021-64326257 · [email protected]
Syntechem Co.,Ltd[email protected]
上海迈瑞尔生化科技有限公司4006356688 18621169109 · [email protected]
阿法埃莎（中国）化学有限公司400-6106006 · [email protected]
安耐吉化学&3A（安徽泽升科技股份有限公司）400-0056266 · [email protected]
北京绿百草科技发展有限公司010-61136123 · [email protected]
上海瀚鸿科技股份有限公司021-54306202 13764082696 · [email protected]
山东省立帆化工有限公司17864861555 · [email protected]
山东西亚化学有限公司13355009207 13355009207 · [email protected]
玛雅试剂+86 (573) 82222445 (0)18006601000 452520369 · [email protected]
四川库利南科技有限公司400-1166-196 18981987031 · [email protected]
天津希恩思生化科技有限公司400 638 7771 · [email protected]
Connect Chemicals GmbH+49 2102 2077 19 · [email protected]
斯百全化学（上海）有限公司021-021-021-67601398-809-809-809 15221380277 · [email protected]
赛默飞世尔科技（中国）有限公司800-810-5118 · [email protected]
北京伊诺凯科技有限公司400-810-7969 010-59572699 · [email protected]
TCI AMERICA800-4238616 · [email protected]
TOKYO CHEMICAL INDUSTRY CO., LTD.03-36680489 · [email protected]
TCI Europe320-37350700 · [email protected]
上海贤鼎生物科技有限公司4009209199 · [email protected]
深圳康特腾科技有限公司86-0755-86635001 · [email protected]
北京环宇世纪化学科技有限公司hysj_bj.com
上海楷树化学科技有限公司021-51987688-803 18916626396 · [email protected]
郑州鸿晟医药科技有限公司0371-0371-13526885213 15637198702 · [email protected]
成都零六生物科技有限公司400-1166-196 13458535857 · [email protected]
上海创赛科技有限公司400-6087598 15021221957 · [email protected]
上海麦克林生化科技股份有限公司15221275939 15221275939 · [email protected]
杭州杰恒化工有限公司0571-87396432 · [email protected]
上海永叶生物科技有限公司86-021-61559134 15921386130 · [email protected]
上海凯赛化工有限公司021-33516722 13701817765 · [email protected]
吉林中科研伸科技有限公司0431-80534353 19917294565 · [email protected]
Sigma-Aldrich西格玛奥德里奇(上海)贸易有限公司021-61415566 800-8193336 · [email protected]
桦特昇生物科技（武汉）有限公司027-59207879 1972026995 18140587686 · [email protected]
大连易得瑞化工有限公司15141125520 15141125520 · [email protected]
成都瑞欧克科技有限公司028-64353063 · [email protected]
厦门志信化学有限公司+86-5922680277 +86-13806087780 · [email protected]
广东翁江化学试剂有限公司0751-2886766 13927870850 · [email protected]
上海大然化学有限公司021-64478606 15900664856 · [email protected]
成都润泽本土化工有限公司028-88469284 18000562381 · [email protected]
上海岚克医药科技发展有限公司0086-21-58956006
Additional notes
DefinitionChEBI: A tetracarboxylic acid that is benzene substituted by four carboxy groups at positions 1, 2, 4 and 5 respectively.
Related reactions
14 records
Linked notes
Loading…