Basic information
- CAS
157355-81-2- Standard SMILES
C[C@H](O)[C@@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O- InChIKey
OYULCCKKLJPNPU-APPDUMDISA-N- Molecular formula
- C19H19NO5
- Average molar mass
- 341.4 g/mol
- Monoisotopic mass
- 341.12632271
Names & identifiers
- Preferred name
- (2R,3S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-hydroxybutanoic acid
- IUPAC
- (2R,3S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-hydroxybutanoic acid
- English name
- (((9H-Fluoren-9-yl)methoxy)carbonyl)-D-threonine
- Molecular formula
- C19H19NO5
- Molecular weight
- 341.36
Names & synonyms
(2R,3S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-hydroxybutanoic acid(2R,3S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-hydroxybutanoic acidRefChem:397535857-384-5Fmoc-D-threonine157355-81-2Fmoc-D-Thr-OHN-[(9H-Fluoren-9-ylmethoxy)carbonyl]-D-threonine(((9H-Fluoren-9-yl)methoxy)carbonyl)-D-threonineMFCD00153365D-Threonine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-N-Fmoc-D-threonine
Show more names
FMOC-D-THR-OH USP/EP/BPFMOC-D-THREONINE extrapureN-Fmoc-D-threonine Fmoc-D-Thr-OHN-(9-Fluorenylmethoxycarbonyl)-D-threonineN-α-(9-Fluorenylmethoxycarbonyl)-D-threonineN-[(9H-Fluoren-9-ylmethoxy)carbonyl]-D-threonine>
(2R,3S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-hydroxybutanoic acidAS-10558N-ALPHA-FMOC-D-THREONINEN-Fmoc-D-Thr(OH)Fmoc-D-Thr-OH.nH2OG7LP4X3WPMA883505Fmoc-D-Thr-OH, AldrichCPR
Properties
Computed structural properties
- XLogP
- 2.4
- Topological polar surface area
- 95.9 Ų
- Hydrogen bond donors
- 3
- Hydrogen bond acceptors
- 5
- Rotatable bonds
- 6
- Heavy atoms
- 25
- Formal charge
- 0
- Complexity
- 474
Physicochemical properties
- Boiling point
- 596.5 · 596.5±50.0 °C(Predicted)
- Density
- 1.327 · 1.327±0.06 g/cm3(Predicted)
- refractive index
- 15 ° · 15 ° (C=1, DMF)
- storage temp.
- 2 · 2-8°C
- solubility
- soluble in Methanol
- form
- powder to crystal
- pka
- 3.49 · 3.49±0.10(Predicted)
- color
- White to Almost white
- Major Application
- peptide synthesis
- InChI
- 1S/C19H19NO5/c1-11(21)17(18(22)23)20-19(24)25-10-16-14-8-4-2-6-12(14)13-7-3-5-9-15(13)16/h2-9,11,16-17,21H,10H2,1H3,(H,20,24)(H,22,23)/t11-,17+/m0/s1
- InChIKey
- OYULCCKKLJPNPU-APPDUMDISA-N
- SMILES
- N([C@H]([C@@H](O)C)C(=O)O)C(=O)OCC1c2c(cccc2)c3c1cccc3
- CAS DataBase Reference
- 157355 · 157355-81-2
- UNSPSC Code
- 12352209 · 12352209
- NACRES
- 22 · NA.22
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
Warning
H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)
The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.
Hazard information
Hazard Classes and CategoriesSkin Irrit. 2 (100%)
Safety data
- wgk
- WGK 2
- hs_code
- 29225090
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- safety_code
- 24/25
- Storage Class
- 11 - Combustible Solids
- Hazard statements
- H315-H319-H335
- Precautionary statements
- P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P362+P364-P403+P233-P501c
Chemistry & industry
Applications
UsesN-Fmoc-D-threonine is an N-Fmoc-protected form of D-Threonine (T405525). D-Threonine is the unnatural isomer of L-Threonine (T405500) and is known to inhibit growth and cell wall synthesis of Mycobacterium smegmatis. D-Threonine is also used as a synthetic intermediate for the production of chiral antibiotics.
Suppliers57 total
梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
上海炎泽化工有限公司15345144255 19975051755 · [email protected]
杭州品高化工有限公司0571-87658025 · [email protected]
杭州摩库生物医药科技有限公司+86-057181025280; +8617767106207 · [email protected]
Dayang Chem (Hangzhou) Co.,Ltd.+86-0571-88938639 17705817739 · [email protected]
浙江珲达生物科技有限公司0571-89903022 18679456698 · [email protected]
上海迈瑞尔生化科技有限公司4006356688 18621169109 · [email protected]
安耐吉化学&3A（安徽泽升科技股份有限公司）400-0056266 · [email protected]
上海瀚鸿科技股份有限公司021-54306202 13764082696 · [email protected]
United Life Science020-82099279 18988968278 · [email protected]
Related reactions
1 records
Compound notes
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