6-Methoxy-8-quinolinamine

HCID 7023

Notes Reactions

Substructure search Find similar structures

Basic information

CAS: 90-52-8
Standard SMILES: COc1cc(N)c2ncccc2c1
InChIKey: YGGTVPCTAKYCSQ-UHFFFAOYSA-N
Molecular formula: C10H10N2O
Average molar mass: 174.2 g/mol
Monoisotopic mass: 174.07931294

Names & identifiers

Preferred name: 6-Methoxy-8-quinolinamine
IUPAC: 6-methoxyquinolin-8-amine
English name: 8-Amino-6-methoxyquinoline
Molecular formula: C10H10N2O
Molecular weight: 174.2

Names & synonyms

8-Amino-6-methoxyquinoline90-52-86-methoxyquinolin-8-amine6-Methoxy-8-aminoquinoline8-Quinolinamine, 6-methoxy-Amichin6-Methoxy-8-quinolinamine8-Quinolineamine, 6-methoxy-6-Methoxy-8-quinolylamineQUINOLINE, 8-AMINO-6-METHOXY-35HXP99PXFEINECS 202-001-3

Show more names

wr15081AKOS BBS-00000172IFLAB-BB F1901-01476-methoxy-8-quinolinaminAmino-6-methoxyquinloline8-amino-6-methoxy-quinolin

NSC 135736-Methoxyquinolin-8-ylamineNSC 119507BRN 0133397WR 15081NSC-13573NSC-119507DTXSID30237983

Database identifiers

CAS: 90-52-8
PubChem CID: 7023
DTXSID: DTXSID30237983
ChEMBL: CHEMBL1759
UNII: 35HXP99PXF
EC Number: 202-001-3
Nikkaji: J48.196C

Properties

Computed structural properties

XLogP: 1.4
Topological polar surface area: 48.1 Å²
Hydrogen bond donors: 1
Hydrogen bond acceptors: 3
Rotatable bonds: 1
Heavy atoms: 13
Formal charge: 0
Complexity: 174

Physicochemical properties

Melting point: 41 °C · 41 °C
Boiling point: 137 · 137-138 °C(Press: 1 Torr)
Density: 1.217 · 1.217±0.06 g/cm3(Predicted)
storage temp.: 2 · under inert gas (nitrogen or Argon) at 2–8 °C
solubility: DMSO (Slightly), Methanol (Slightly)
form: Solid
pka: 3.49 · 3.49±0.10(Predicted)
color: Brown to Very Dark Brown
Stability: Incompatible with strong oxidizing agents.
CAS DataBase Reference: 90 · 90-52-8(CAS DataBase Reference)
FDA UNII: 35 HXP99PXF · 35HXP99PXF
Symbol(GHS): 7 · GHS07
Signal word: Warning
Hazard statements: 319 · H319-H315
Precautionary statements: 264 · P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362
HazardClass: IRRITANT
HS Code: 2933499090 · 2933499090

Safety & regulation

GHS classification

GHS Classification · 4 items

Warning

H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]

P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 2 reports by companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Hazard information

Hazard Classes and CategoriesSkin Irrit. 2 (100%)

Safety data

hs_code: 2933499090
Signal word: Warning
Symbol(GHS): GHS07
hazard_class: IRRITANT
Hazard statements: H319-H315
Precautionary statements: P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362

Chemistry & industry

Applications

Uses8-Amino-6-methoxyquinoline has oxidizing properties as well as potential anti-tuberculosis application with its antimycobacterial messages as well.