2-Methyl-2-oxazoline (HCID 70713)

Names & identifiers

Preferred name: 2-Methyl-2-oxazoline
IUPAC: 2-methyl-4,5-dihydro-1,3-oxazole
English name: 2-Methyl-2-oxazoline
Molecular formula: C4H7NO
Molecular weight: 85.1

Names & synonyms

2-Methyl-2-oxazoline1120-64-52-Methyl-4,5-dihydro-1,3-oxazoleCHEBI:53614DTXSID40870845RefChem:475175DTXCID90818530214-316-32-methyl-4,5-dihydrooxazole2-MethyloxazolineOxazole, 4,5-dihydro-2-methyl-MFCD00005298

Show more names

NSC 43141-METHYL-2-OXAZOLINE2-Methyl-2-oxazoline>2-Methyl-2-oxazoline 98%2-Methyl-2-oxazoline,99%4,5-Dihydro-2-methyloxazole2-METHYL-4,5-DIHYDRO-OXAZOLE

26375-28-02-Methyl-2-oxazolin2-methyl-1,3-oxazolineOxazole, 4,5-dihydro-2-methyl-, homopolymer2-Oxazoline, 2-methyl-methyl oxazoline2-methyl-oxazolineNSC43141

Database identifiers

CAS: 1120-64-5
PubChem CID: 70713
DTXSID: DTXSID40870845
ChEBI: CHEBI:53614
EC Number: 214-316-3
Nikkaji: J24.397C

Properties

Computed structural properties

XLogP: -0.2
Topological polar surface area: 21.6 Å²
Hydrogen bond donors: 0
Hydrogen bond acceptors: 2
Rotatable bonds: 0
Heavy atoms: 6
Formal charge: 0
Complexity: 77

Experimental & physicochemical properties

Physical DescriptionColorless liquid; [Acros Organics MSDS]

Physicochemical properties

Boiling point: 109.5 · 109.5-110.5 °C(lit.)
Density: 1.005 g/mL · 1.005 g/mL at 25 °C(lit.)
refractive index: 20 · n20/D 1.434(lit.)
Flash point: 68 °F · 68 °F
storage temp.: Sealed in dry,Room Temperature
form: Liquid
pka: 5.77 · 5.77±0.50(Predicted)
Specific Gravity: 1.01 · 1.01
color: Clear colorless to very faint yellow
Water Solubility: Soluble in water (7051 mg/L at 25°C).
BRN: 104227 · 104227
InChI: InChI=1S/C4H7NO/c1-4-5-2-3-6-4/h2-3H2,1H3
InChIKey: GUXJXWKCUUWCLX-UHFFFAOYSA-N
SMILES: O1CCN=C1C
LogP: 0.058 · 0.058 (est)
CAS DataBase Reference: 1120 · 1120-64-5(CAS DataBase Reference)
UNSPSC Code: 12352100 · 12352100
NACRES: 22 · NA.22
Symbol(GHS): 2 · GHS02
Signal word: Danger
Hazard statements: 225 · H225
Precautionary statements: 210 · P210
PPE: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
Hazard Codes: F
Risk Statements: 11 · 11
Safety Statements: 23 · 23-24/25
RIDADR: 1993 · UN 1993 3/PG 2
WGK Germany: 3 · 3
HazardClass: 3 · 3
PackingGroup: II
HS Code: 29339900 · 29339900
Storage Class: 3 · 3 - Flammable liquids
Hazard Classifications: 2 · Flam. Liq. 2
Limited Quantities: 1 L · 1.0 L (0.3 gallon) (liquid)
Excepted Quantities: Max Inner Pack (30g or 30ml) and Max Outer Pack (500g or 500ml)

Safety & regulation

GHS classification

GHS Classification · 5 items

Danger

H225 (97.9%): Highly Flammable liquid and vapor [Danger Flammable liquids]

P210, P233, P240, P241, P242, P243, P280, P303+P361+P353, P370+P378, P403+P235, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 48 reports by companies from 4 notifications to the ECHA C&L Inventory.；Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

Hazard information

Hazards SummaryMay cause irritation; [Acros Organics MSDS]

Hazard Classes and CategoriesFlam. Liq. 2 (97.9%)

Safety data

PPE: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
wgk: 3
ridadr: UN 1993 3/PG 2
hs_code: 29339900
risk_code: 11
Signal word: Danger
Symbol(GHS): GHS02
hazard_code: F
safety_code: 23-24/25
hazard_class: 3
Storage Class: 3 - Flammable liquids
packing_group: II
Hazard statements: H225
Limited Quantities: 1.0 L (0.3 gallon) (liquid)
Excepted Quantities: Max Inner Pack (30g or 30ml) and Max Outer Pack (500g or 500ml)
Hazard Classifications: Flam. Liq. 2
Precautionary statements: P210

Chemistry & industry

Applications · 2 items

Uses2-Methyl-2-oxazoline is used in cationic polymerization of a series of linear 2-alkyl-2-oxazolines under microwave irradiation. It undergoes polymerization with 2-butyl-2-oxazoline to form poly(2-oxazoline) block copolymer. It undergoes cationic ring-opening polymerization with 2-(dec-9-enyl)-2-oxazoline to yield copoly(2-oxazoline)s. It react with N'-phenyl-benzohydrazonoyl chloride to get 4-(2-hydroxyethyl)-5-methyl-1,3-diphenyl-1,2,4-triazol-4-ium chloride.

General Description2-Methyl-2-oxazoline undergoes polymerization with 2-butyl-2-oxazoline to form poly(2-oxazoline) block copolymer. It undergoes cationic ring-opening polymerization with 2-(dec-9-enyl)-2-oxazoline to yield copoly(2-oxazoline)s.

Upstream & downstream products

Upstream raw materials

Suppliers50 total

梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]

上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]

南京凯美西化工有限公司02558748998 18951874644 · [email protected]

上海麦克林生化科技股份有限公司021-50706066 15221275939 · [email protected]

山东川成医药有限公司06355032777 17606225562

Additional notes

DefinitionChEBI: A 5-membered heterocyclic compound, which is substituted in the 2-position with a methyl group and which is often used as a monomer in polymerisation reactions.