Basic information
- CAS
1155-62-0- Standard SMILES
O=C(O)CC[C@H](NC(=O)OCc1ccccc1)C(=O)O- InChIKey
PVFCXMDXBIEMQG-JTQLQIEISA-N- Molecular formula
- C13H15NO6
- Average molar mass
- 281.26 g/mol
- Monoisotopic mass
- 281.0899372
Names & identifiers
- Preferred name
- L-Glutamic acid, N-((phenylmethoxy)carbonyl)-
- IUPAC
- (2S)-2-(phenylmethoxycarbonylamino)pentanedioic acid
- English name
- N-Cbz-L-glutamic acid
- Molecular formula
- C13H15NO6
- Molecular weight
- 281.26
Names & synonyms
N-Carbobenzoxy-L-glutamic acidL-Glutamic acid, N-[(phenylmethoxy)carbonyl]-N-Benzyloxycarbonylglutamic acidNSC 555NSC 88494N-[(PHENYLMETHOXY)CARBONYL]-L-GLUTAMIC ACIDEINECS 214-584-1Glutamic acid, N-carboxy-, N-benzyl ester, L-N-((Phenylmethoxycarbonyl)-L-glutamic acidN-((Phenylmethoxy)carbonyl)-L-glutamic acidL-Glutamic acid, N-((phenylmethoxy)carbonyl)-DTXSID70883660
Show more names
CBZ-GLU-OHZ-GLUCBZ-L-GLUTAMIC ACIDZ-L-GLU-OHCBZ-L-Glu-OHPHQ-GLU
RefChem:796308DTXCID9010231671155-62-0N-Cbz-L-glutamic acidZ-Glu-OHCarbobenzoxy-L-glutamic acidN-Carbobenzyloxy-l-glutamic acid(S)-2-(((BENZYLOXY)CARBONYL)AMINO)PENTANEDIOIC ACID
Database identifiers
- CAS
1155-62-0- PubChem CID
- 70866
- DTXSID
DTXSID70883660
Properties
Computed structural properties
- XLogP
- 0.9
- Topological polar surface area
- 113 Ų
- Hydrogen bond donors
- 3
- Hydrogen bond acceptors
- 6
- Rotatable bonds
- 8
- Heavy atoms
- 20
- Formal charge
- 0
- Complexity
- 351
Physicochemical properties
- Melting point
- 115 · 115-117 °C(lit.)
- alpha
- -7.4 · -7.4 º (c=10, CH3COOH 22 ºC)
- Boiling point
- 423.93 °C · 423.93°C (rough estimate)
- Density
- 1.2801 · 1.2801 (rough estimate)
- refractive index
- -7.5 ° · -7.5 ° (C=8, AcOH)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- DMF, Methanol
- form
- Solid
- pka
- 3.81 · 3.81±0.10(Predicted)
- color
- Off-White
- optical activity
- 22 · [α]22/D 7.4°, c = 10 in acetic acid
- BRN
- 2061272 · 2061272
- Major Application
- peptide synthesis
- InChI
- InChI=1S/C13H15NO6/c15-11(16)7-6-10(12(17)18)14-13(19)20-8-9-4-2-1-3-5-9/h1-5,10H,6-8H2,(H,14,19)(H,15,16)(H,17,18)/t10-/m0/s1
- InChIKey
- PVFCXMDXBIEMQG-JTQLQIEISA-N
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
Safety data
- PPE
- Eyeshields, Gloves, type N95 (US)
- wgk
- 3
- tsca
- TSCA listed
- hs_code
- 29242990
- risk_code
- 20/21/22-36/37/38
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- hazard_code
- Xn
- safety_code
- 22-24/25-36-26
- hazard_class
- IRRITANT
- Storage Class
- 11 - Combustible Solids
- Hazard statements
- H302-H315-H319-H335
- Precautionary statements
- P261-P301+P312-P302+P352-P304+P340-P305+P351+P338
Chemistry & industry
Uses & manufacturing
General Manufacturing InformationL-Glutamic acid, N-[(phenylmethoxy)carbonyl]-: INACTIVE
Applications
UsesUsed for the synthesis of carboxyalkyl peptides as inhibitors of angiotensin-converting enzyme of human blood serum.
UsesN-Cbz-L-glutamic acid is used for the synthesis.
Upstream & downstream products
Upstream raw materials
Downstream products
Suppliers100 total
北京华美互利生物化工010-56205725 · [email protected]
梯希爱(上海)化成工业发展有限公司
Related reactions
11 records
Compound notes
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