2,6-Pyridinedimethanol

HCID 70957
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Basic information

CAS
1195-59-1
Standard SMILES
OCc1cccc(CO)n1
InChIKey
WWFMINHWJYHXHF-UHFFFAOYSA-N
Molecular formula
C7H9NO2
Average molar mass
139.15 g/mol
Monoisotopic mass
139.06332853

Names & identifiers

Preferred name
2,6-Pyridinedimethanol
IUPAC
[6-(hydroxymethyl)-2-pyridinyl]methanol
English name
2,6-Pyridinedimethanol
Molecular formula
C7H9NO2
Molecular weight
139.15

Names & synonyms

2,6-Pyridinedimethanol1195-59-1Pyridine-2,6-diyldimethanolDTXSID20152474RefChem:870724DTXCID1074965214-803-0[6-(hydroxymethyl)pyridin-2-yl]methanol2,6-Bis(hydroxymethyl)pyridine2,6-DIHYDROXYMETHYLPYRIDINEMFCD0000635126-Pyridinedimethanol
Show more names
(6-Hydroxymethyl-pyridin-2-yl)-methanol2,6-PYRIDINETHANOL2,6-PYRIDINEMETHANOL BIS2,6-Pyridinedimethanol ,98%2,6-PyridinediMethanol, 98% 5GR2,6-PyridinediMethanol SynonyMs 2,6-PyridyldicarbinolRARECHEM AL BD 0203
Pyridine-2,6-dimethanol[6-(hydroxymethyl)-2-pyridyl]methanol2,6-Bis-(hydroxymethyl)pyridine[6-(hydroxymethyl)-2-pyridyl]methan-1-ol(2,6-PYRIDINYL)DIMETHANOLpyridine 2,6-dimethanol(Pyridine-2,6-diyl)dimethanol2,6-bis-(hydroxymethyl)-pyridine

Database identifiers

CAS
1195-59-1
PubChem CID
70957
DTXSID
DTXSID20152474
EC Number
214-803-0
Nikkaji
J41.162K

Properties

Computed structural properties

XLogP
-0.8
Topological polar surface area
53.4 Ų
Hydrogen bond donors
2
Hydrogen bond acceptors
3
Rotatable bonds
2
Heavy atoms
10

Physicochemical properties

Melting point
112 · 112-114 °C (lit.)
Boiling point
185 °C · 185°C 15mm
Density
1.1997 · 1.1997 (rough estimate)
refractive index
1.48 · 1.4800 (estimate)
Flash point
185 °C/15mm · 185°C/15mm
storage temp.
Inert atmosphere,Room Temperature

Safety & regulation

GHS classification

GHS Classification · 5 items

Danger

H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]；H318 (96.1%): Causes serious eye damage [Danger Serious eye damage/eye irritation]；H335 (96.1%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P354+P338, P317, P319, P321, P332+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 51 reports by companies from 7 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.；Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

Hazard information

Regulatory InformationStatus: Active Update: 01-10-2020 https://echa.europa.eu/registration-dossier/-/registered-dossier/31701
Hazard Classes and CategoriesSkin Irrit. 2 (100%)；Eye Dam. 1 (96.1%)；STOT SE 3 (96.1%)

Regulatory information

Regulatory InformationStatus: Active Update: 01-10-2020 https://echa.europa.eu/registration-dossier/-/registered-dossier/31701

Safety data

F
23
PPE
dust mask type N95 (US), Eyeshields, Gloves
wgk
3
hs_code
29333999
risk_code
37/38-41-36/37/38
Signal word
Danger

Chemistry & industry

Applications

Uses2,6-Pyridinedimethanol can be used as a quantum dot solution for photoelectric device and biomedicine and also a ligand to synthesize a variety of metal complexes and catalysts.

Preparation methods · 1 item

PreparationThe preparation of 2,6-Pyridinedimethanol is as follows:2640g of 2,6-dibromomethylpyridine, 3L of 30% aqueous sodium hydroxide solution, and 10L of ethanol were placed in a 20L reaction flask. Turn on the agitation. The reaction solution was heated to reflux and the reaction was kept for 5h. The TLC to intermediate state reaction is complete. The reaction solution is cooled to room temperature, plus into 20L of ice water, stir for 20min. The aqueous phase was extracted twice with 10L of dichloromethane and the organic phases were combined. The organic phase is concentrated under reduced pressure to dry, a solid of 1232g was obtained, the yield was 88.6%, and the liquid phase was 98%.

Upstream & downstream products

Suppliers100 total

梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
衢州润东化工有限公司0570-8789886 18892685668 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
INTATRADE GmbH+49 3493/605464 · [email protected]
韶远科技（上海）有限公司021-50795510 4000665055 · [email protected]

Related reactions

13 records
New reaction record

Compound notes

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