4,4'-Dihydroxybiphenyl

Dry Powder; Other Solid

Off-white, light beige, or light gray odorless powder; [Acros Organics MSDS]

1979

2046

This chemical does not meet GHS hazard criteria for 0.5% (1 of 211) of reports.

Warning

H312 (44.1%): Harmful in contact with skin [Warning Acute toxicity, dermal]；H315 (26.1%): Causes skin irritation [Warning Skin corrosion/irritation]；H317 (55.9%): May cause an allergic skin reaction [Warning Sensitization, Skin]；H319 (25.6%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]；H335 (25.1%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]；H411 (18.5%): Toxic to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard]；H412 (55.5%): Harmful to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard]

P261, P264, P264+P265, P271, P272, P273, P280, P302+P352, P304+P340, P305+P351+P338, P317, P319, P321, P332+P317, P333+P317, P337+P317, P362+P364, P391, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 211 reports by companies from 15 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.；Reported as not meeting GHS hazard criteria per 1 of 211 reports by companies.；There are 14 notifications provided by 210 of 211 reports by companies with hazard statement code(s).；Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

Chemical: [1,1'-Biphenyl]-4,4'-diol

[1,1'-Biphenyl]-4,4'-diol is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of [1,1'-Biphenyl]-4,4'-diol are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Status: Active Update: 30-03-2023 https://echa.europa.eu/registration-dossier/-/registered-dossier/15910；Status: Active Update: 07-03-2018 https://echa.europa.eu/registration-dossier/-/registered-dossier/22776

Showed estrogenic activity in Saccharomyces cerevisiae hER in vivo assays; [EPA - TSCATS] Abnormal urinalysis, reversible gross and histopathological liver changes in males, and no evidence of reproductive or developmental toxicity observed in oral study of rats; [JECDB] May cause skin sensitization; [ECHA REACH Registrations] An irritant; Harmful by skin absorption; [Acros Organics MSDS] See Biphenyl.

Acute Tox. 4 (44.1%)；Skin Irrit. 2 (26.1%)；Skin Sens. 1 (55.9%)；Eye Irrit. 2 (25.6%)；STOT SE 3 (25.1%)；Aquatic Chronic 2 (18.5%)；Aquatic Chronic 3 (55.5%)

Acute toxicity (Dermal) - Category 4；Germ cell mutagenicity - Category 2；Hazardous to the aquatic environment (Acute) - Category 2；Hazardous to the aquatic environment (Long-term) - Category 2

Skin sensitization - Category 1；Hazardous to the aquatic environment (Acute) - Category 2；Hazardous to the aquatic environment (Long-term) - Category 2

Chemical: [1,1'-Biphenyl]-4,4'-diol

[1,1'-Biphenyl]-4,4'-diol is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of [1,1'-Biphenyl]-4,4'-diol are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Status: Active Update: 30-03-2023 https://echa.europa.eu/registration-dossier/-/registered-dossier/15910；Status: Active Update: 07-03-2018 https://echa.europa.eu/registration-dossier/-/registered-dossier/22776

All Other Chemical Product and Preparation Manufacturing；Plastics Material and Resin Manufacturing

[1,1'-Biphenyl]-4,4'-diol: ACTIVE