Talopram Hydrochloride
Basic information
- CAS
7013-41-4- Standard SMILES
CNCCCC1(c2ccccc2)OC(C)(C)c2ccccc21.Cl- InChIKey
JZXJIRQPHHWYGC-UHFFFAOYSA-N- Molecular formula
- C20H26ClNO
- Average molar mass
- 331.9 g/mol
- Monoisotopic mass
- 331.1702921
Overview
See also: Talopram (has active moiety).
Names & identifiers
- Preferred name
- Talopram Hydrochloride
- IUPAC
- 3-(3,3-dimethyl-1-phenyl-2-benzofuran-1-yl)-N-methylpropan-1-amine;hydrochloride
- English name
- Talopram
- Molecular formula
- C20H26ClNO
- Molecular weight
- 331.88
Names & synonyms
Talopram hydrochloride7013-41-4Talopram HClLU 3-010Talopram hydrochloride [USAN]lu3-010Phtalapromine hydrochlorideAY-21,554NSC 104350UNII-0X97008FCC0X97008FCCN,3,3-Trimethyl-1-phenyl-1-phthalanpropylamine hydrochloride
Show more names
Talopram1,3-Dihydro-N,3,3-trimethyl-1-phenyl-1-isobenzofuranpropanamine hydrochloride
NSC-104350AY 21554AY-21554LU-3-0101-Isobenzofuranpropanamine, 1,3-dihydro-N,3,3-trimethyl-1-phenyl-, hydrochlorideTalopram hydrochloride (USAN)1-Phthalanpropylamine, 1-phenyl-N,3,3-trimethyl-, hydrochloride1-Phthalanpropylamine, N,3,3-trimethyl-1-phenyl-, hydrochloride
Database identifiers
- CAS
7013-41-4- PubChem CID
- 71176
- DTXSID
DTXSID601020621- ChEMBL
CHEMBL2105328- UNII
- 0X97008FCC
- EC Number
- 804-153-1
Properties
Computed structural properties
- Topological polar surface area
- 21.3 Ų
- Hydrogen bond donors
- 2
- Hydrogen bond acceptors
- 2
- Rotatable bonds
- 5
- Heavy atoms
- 23
- Formal charge
- 0
- Complexity
- 361
Physicochemical properties
- Melting point
- 190 · 190-191 °C
- storage temp.
- Desiccate at RT
- solubility
- 50 mM · Soluble to 50 mM in water and to 100 mM in DMSO
- form
- Powder
- FDA UNII
- 0 X97008FCC · 0X97008FCC
- Symbol(GHS)
- 7 · GHS07
- Signal word
- Warning
- Hazard statements
- 302 · H302
- Precautionary statements
- 264 · P264-P270-P301+P312-P330-P501
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
Warning
H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]
P264, P270, P301+P317, P330, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 38 reports by companies from 1 notifications to the ECHA C&L Inventory.
Hazard information
Hazard Classes and CategoriesAcute Tox. 4 (100%)
Safety data
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- Hazard statements
- H302
- Precautionary statements
- P264-P270-P301+P312-P330-P501
Chemistry & industry
Applications
UsesTalopram Hydrochloride can reverse the effects of Tetrabenazine (T284000), a dopamine depleting agent and antipsychotic, in vitro and is considered to be an antidepressant.
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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