Basic information
- CAS
77862-92-1- Standard SMILES
COc1ccc(CCN(C)CCCN2Cc3cc(OC)c(OC)cc3C2=O)cc1OC- InChIKey
UUMGNNQOCVDZDG-UHFFFAOYSA-N- Molecular formula
- C24H32N2O5
- Average molar mass
- 428.5 g/mol
- Monoisotopic mass
- 428.23112213
Overview
Falipamil is a small molecule drug. Falipamil has a monoisotopic molecular weight of 428.23 Da.
Names & identifiers
- Preferred name
- Falipamil
- IUPAC
- 2-[3-[2-(3,4-dimethoxyphenyl)ethyl-methylamino]propyl]-5,6-dimethoxy-3H-isoindol-1-one
- English name
- Falipamil
- Molecular formula
- C24H32N2O5
- Molecular weight
- 428.52
Names & synonyms
Falipamil77862-92-1FalipamilumfalipamiloAQ-A-39N6A93ZMN7UDTXSID702284765,6-dimethoxy-2-(3-((alpha-(3,4-dimethoxy)phenylethyl)methylamino)propyl)phthalimidine1H-Isoindol-1-one, 2-(3-((2-(3,4-dimethoxyphenyl)ethyl)methylamino)propyl)-2,3-dihydro-5,6-dimethoxy-AQA 39AQ-AH-208RefChem:139906
Show more names
2-[3-[2-(3,4-Dimethoxyphenyl)ethyl(methyl)amino]propyl]-2,3-dihydro-5,6-dimethoxy-1H-isoindol-1-one2-[3-[[2-(3,4-Dimethoxyphenyl)ethyl]methylamino]propyl]-2,3-dihydro-5,6-dimethoxy-1H-isoindol-1-one1H-Isoindol-1-one, 2-[3-[[2-(3,4-dimethoxyphenyl)ethyl]methylamino]propyl]-2,3-dihydro-5,6-dimethoxy-
AQ-A39DTXCID90150967Falipamil [INN]AQ-A 392-[3-[2-(3,4-dimethoxyphenyl)ethyl-methylamino]propyl]-5,6-dimethoxy-3H-isoindol-1-oneFalipamilum [INN-Latin]UNII-N6A93ZMN7U2-[3-[[2-(3,4-Dimethoxyphenyl)ethyl]methylamino]propyl]-2,3-dihydro-5,6-dimethoxy-1H-isoindol-1-one; AQ-A 39;
Database identifiers
- CAS
Properties
Computed structural properties
- XLogP
- 3.2
- Topological polar surface area
- 60.5 Ų
- Hydrogen bond donors
- 0
- Hydrogen bond acceptors
- 6
- Rotatable bonds
- 11
- Heavy atoms
- 31
- Formal charge
- 0
- Complexity
- 562
Physicochemical properties
- Boiling point
- 597.1 · 597.1±50.0 °C(Predicted)
- Density
- 1.146 · 1.146±0.06 g/cm3(Predicted)
- storage temp.
- -20 °C · Hygroscopic, -20°C Freezer, Under inert atmosphere
- solubility
- Chloroform (Slightly), Methanol (Slightly)
- form
- Gel
- pka
- 8.98 · 8.98±0.50(Predicted)
- color
- Brown to Dark Yellow
- Stability
- Hygroscopic
- FDA UNII
- 6 A93ZMN7U · N6A93ZMN7U
Chemistry & industry
Pharmacology
MeSH Pharmacological Classification
Agents used for the treatment or prevention of cardiac arrhythmias. They may affect the polarization-repolarization phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibers. Anti-arrhythmia agents are often classed into four main groups according to their mechanism of action: sodium channel blockade, beta-adrenergic blockade, repolarization prolongation, or calcium channel blockade.
A class of drugs that act by selective inhibition of calcium influx through cellular membranes.
Agents that affect the rate or intensity of cardiac contraction, blood vessel diameter, or blood volume.
Agents that inhibit the actions of the parasympathetic nervous system. The major group of drugs used therapeutically for this purpose is the MUSCARINIC ANTAGONISTS.
Applications
UsesFalipamil is a specific bradycardic agent and a calcium channel blocker.
Suppliers4 total
上海陶术生物科技股份有限公司+1-781-999-5354; +1-00000000000 · [email protected]
艾吉析科技（上海）有限公司17717235263 17717235263 · [email protected]
上海陶术生物科技股份有限公司13564774135 · [email protected]
TargetMol中国（陶术生物）15002134094 · [email protected]
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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