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Basic information
- CAS
80428-29-1- Standard SMILES
COc1cc(NC(C)=O)ccc1OCCCN1CCN(c2ccccc2F)CC1- InChIKey
PHOCQBYGUQPMIB-UHFFFAOYSA-N- Molecular formula
- C22H28FN3O3
- Average molar mass
- 401.482 g/mol
- Monoisotopic mass
- 401.21146998
Names & identifiers
- Preferred name
- Mafoprazine
- IUPAC
- N-(4-{3-[4-(2-Fluorophenyl)piperazin-1-yl]propoxy}-3-methoxyphenyl)acetamide
- English name
- Mafoprazine
- Molecular formula
- C22H28FN3O3
- Molecular weight
- 401.47
Names & synonyms
MafoprazineMafoprazine StandardN-(4-{3-[4-(2-FLUOROPHENYL)PIPERAZIN-1-YL]PROPOXY}-3-METHOXYPHENYL)ACETAMIDEAcetamide, N-[4-[3-[4-(2-fluorophenyl)-1-piperazinyl]propoxy]-3-methoxyphenyl]-
Database identifiers
- CAS
80428-29-1- PubChem CID
- 71241
- DTXSID
DTXSID50230310- ChEMBL
CHEMBL2105101- UNII
- D7UUO54C6N
- Nikkaji
- J138.354J
Properties
Physicochemical properties
- Melting point
- 123 ℃ · approximate 123℃ (dec.)
- Boiling point
- 590.5 · 590.5±50.0 °C(Predicted)
- Density
- 1.192 · 1.192±0.06 g/cm3(Predicted)
- pka
- 14.09 · 14.09±0.70(Predicted)
- InChI
- InChI=1S/C22H28FN3O3/c1-17(27)24-18-8-9-21(22(16-18)28-2)29-15-5-10-25-11-13-26(14-12-25)20-7-4-3-6-19(20)23/h3-4,6-9,16H,5,10-15H2,1-2H3,(H,24,27)
- InChIKey
- PHOCQBYGUQPMIB-UHFFFAOYSA-N
- SMILES
- C(NC1=CC=C(OCCCN2CCN(C3=CC=CC=C3F)CC2)C(OC)=C1)(=O)C
- FDA UNII
- 7 UUO54C6N · D7UUO54C6N
Chemistry & industry
Applications
UsesMafoprazine is a phenylpiperazine derivative with variable affinities for neuronal receptors. It may exert its antipsychotic effects primarily through D2 receptor blockade and α-adrenergic activity, and may increase the activity of dopamine metabolites.
Suppliers5 total
杭州摩库生物医药科技有限公司+86-057181025280; +8617767106207 · [email protected]
天津阿尔塔科技有限公司022-6537-8550 15522853686 · [email protected]
ATK CHEMICAL COMPANY LIMITED+undefined-21-51877795 · [email protected]
上海凯裕医药科技有限公司17317130613 · [email protected]
TargetMol中国（陶术生物）15002134094 · [email protected]
Related reactions
2 records
Compound notes
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