Etofenprox
Basic information
- CAS
1705649-55-3- Standard SMILES
CCOc1ccc(C(C)(C)COCc2cccc(Oc3ccccc3)c2)cc1- InChIKey
YREQHYQNNWYQCJ-UHFFFAOYSA-N- Molecular formula
- C25H28O3
- Average molar mass
- 376.5 g/mol
- Monoisotopic mass
- 376.20384476
Overview
Etofenprox is an aromatic ether that is the 3-phenoxybenzyl ether of 2-(4-ethoxyphenyl)-2-methylpropan-1-ol. It has a role as a pyrethroid ether insecticide. It is functionally related to a 2-(4-ethoxyphenyl)-2-methylpropan-1-ol.
Names & identifiers
- Preferred name
- Etofenprox
- IUPAC
- 1-ethoxy-4-[2-methyl-1-[(3-phenoxyphenyl)methoxy]propan-2-yl]benzene
- English name
- Etofenprox
- Molecular formula
- C25H28O3
- Molecular weight
- 376.49
Names & synonyms
Etofenprox80844-07-1Ethofenprox1-((2-(4-Ethoxyphenyl)-2-methylpropoxy)methyl)-3-phenoxybenzeneEthophenproxEtofenproxumDTXSID90326100LD7P9153CDTXCID7012610CHEBI:39348Benzene, 1-((2-(4-ethoxyphenyl)-2-methylpropoxy)methyl)-3-phenoxy-1-{[2-(4-ethoxyphenyl)-2-methylpropoxy]methyl}-3-phenoxybenzene
Show more names
PEPENUKILTREBONmti500VECTRONPUNKASOLenatop
2-(4-ethoxyphenyl)-2-methylpropyl-3-phenoxybenzyl etherRefChem:139268407-980-2Etofenprox [INN]1-ethoxy-4-[2-methyl-1-[(3-phenoxyphenyl)methoxy]propan-2-yl]benzeneMFCD002102872-(4-Ethoxyphenyl)-2-methylpropyl 3-phenoxybenzyl ether1705649-55-3
Database identifiers
- CAS
1705649-55-3、80844-07-1- PubChem CID
- 71245
- DTXSID
DTXSID9032610- ChEMBL
CHEMBL2105573
Properties
Computed structural properties
- XLogP
- 7
- Topological polar surface area
- 27.7 Ų
- Hydrogen bond donors
- 0
- Hydrogen bond acceptors
- 3
- Rotatable bonds
- 9
- Heavy atoms
- 28
- Formal charge
- 0
- Complexity
- 422
Experimental & physicochemical properties
Pesticides
Agrochemicals -> Pesticide active substances
Active substance -> EU Pesticides database: Approved
Environmental transformation -> Pesticides (parent, predecessor)
Pesticide
Insecticides
Pesticide (Etofenprox) -> USDA PDB
LogP7.05
Endocrine DisruptorsPotential endocrine disrupting compound
Collision Cross Section
191.0 Ų [M+Na]+ [CCS Type: DT; Buffer gas: N2; Ionization: ESI+; Dataset: TOXCAST; Source Identifier: DTXSID9032610]
191.81 Ų [M+Na]+
189.38 Ų [M]+ [CCS Type: TW; Buffer gas: N2; Ionization: GC-APCI+]
Physicochemical properties
- Melting point
- 36.4 · 36.4-38.0°
- Boiling point
- 445.03 °C · 445.03°C (rough estimate)
- Density
- 1.1386 · 1.1386 (rough estimate)
- vapor pressure
- 32 · 32×10-3 Pa (100 °C)
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
Warning
H362: May cause harm to breast-fed children [Reproductive toxicity, effects on or via lactation]
P203, P260, P263, P264, P270, P273, P318, P391, and P501 (click each P-code to see the statement)
Warning
H362 (96.7%): May cause harm to breast-fed children [Reproductive toxicity, effects on or via lactation]
P203, P260, P263, P264, P270, P273, P318, P391, and P501 (click each P-code to see the statement)
Hazard information
Regulatory Information
Commission Regulation (EC) No 1490/2002
Etofenprox is listed in the dataset of EPA Human Health Benchmarks for Pesticides under the Safe Drinking Water Act (40 eCFR 141)
2009/77/EC, Reg. (EU) 2021/1449, Reg. (EU) 2022/1480, Reg. (EU) 2023/2592, Reg. (EU) No 540/2011
Status: Cease Manufacture Update: 10-11-2008 https://echa.europa.eu/registration-dossier/-/registered-dossier/4043
Etofenprox: HSNO Approval: HSR003567 Approved with controls
Hazard Classes and Categories
Lact. (75%)
Lact. (96.7%)
Lact. (100%)
Reproductive toxicity - effects on or via lactation
Hazardous to the aquatic environment (Acute) - Category 1
Specific target organ toxicity - Single exposure - Category 1 (central nervous system), Category 3 (narcotic effects)
Toxicology
RAIS Toxicity Values
0.0255
OPP
EPA Human Health Benchmarks for Pesticides
Chemistry & industry
Uses & manufacturing
Household ProductsInformation on 35 consumer products that contain Etofenprox in the following categories is provided:
Use Classification
Environmental transformation -> Pesticides (parent, predecessor)
Insecticides
Applications
DescriptionEtofenprox belongs to a pyrethroid derivative that is commonly used as an insecticide in agriculture, horticulture, viticulture, forestry, animal health and public health against various insect pests. It can be found as an active ingredient in a variety of pest control products, which is effective to control broad spectrum of pests, such as crawling and flying insects. In the field of agriculture, etofenprox can be applied on a broad range of crops, including rice, fruits, vegetables, corn, soybeans and tea, which is poorly absorbed by roots and little translocation occurs within plants. It is also used for the public health by controlling adult mosquitoes, non biting midges, biting and non-biting flies, which may carry the pathogen. Besides, etofenprox can be found as an component in flea and tick medications for dogs and cats. Etofenprox is a new type of insecticide with low mammalian toxicity, which can be decomposed in soil by anaerobic and aerobic microorganisms. It functions by strongly disrupting the transmission of nervous impulses and causes paralysis and death to the target insect.
UsesEtofenprox is used to control a wide variety of insects on fruit, tea, soyabeans and many vegetables. It is also used in public health and animal health.
UsesInsecticide.
Upstream & downstream products
Upstream raw materials
Related reactions
12 records
Compound notes
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