Basic information
- CAS
83275-56-3- Standard SMILES
CCOC(=O)Nc1ccc2c(c1)N(C(=O)CN(C)C)c1ccccc1CC2- InChIKey
KJAMZCVTJDTESW-UHFFFAOYSA-N- Molecular formula
- C21H25N3O3
- Average molar mass
- 367.4 g/mol
- Monoisotopic mass
- 367.18959167
Overview
Tiracizine is a dibenzooxazepine.
Names & identifiers
- Preferred name
- Tiracizine
- IUPAC
- ethyl N-[11-[2-(dimethylamino)acetyl]-5,6-dihydrobenzo[b][1]benzazepin-2-yl]carbamate
- English name
- Carbamic acid
- Molecular formula
- C21H25N3O3
- Molecular weight
- 367.44
Names & synonyms
Tiracizine83275-56-3TiracizinaTiracizinumDTXSID50487149UUO2T61K7DTXCID2028640Ethyl N-[5-[2-(dimethylamino)acetyl]-10,11-dihydro-5H-dibenz[b,f]azepin-3-yl]carbamateAWD-19-166Ethyl N-(5-(2-(dimethylamino)acetyl)-10,11-dihydro-5H-dibenz(b,f)azepin-3-yl)carbamateCarbamic acid, (5-((dimethylamino)acetyl)-10,11-dihydro-5H-dibenz(b,f)azepin-3-yl)-, ethyl ester, monohydrochlorideRefChem:898224
Show more names
Tiracizinum [INN-Latin]ethyl N-[11-[2-(dimethylamino)acetyl]-5,6-dihydrobenzo[b][1]benzazepin-9-yl]carbamateethyl N-[11-[2-(dimethylamino)ethanoyl]-5,6-dihydrobenzo[b][1]benzazepin-9-yl]carbamateN-[11-[2-(dimethylamino)acetyl]-5,6-dihydrobenzo[b][1]benzazepin-9-yl]carbamic acid ethyl esterCarbamic acid, N-[5-[2-(dimethylamino)acetyl]-10,11-dihydro-5H-dibenz[b,f]azepin-3-yl]-, ethyl ester
C01EB11GS-1053-carbethoxyamino-5-dimethylaminoacetyl-2,2'-iminodibenzyl HClethyl N-(2-(2-(dimethylamino)acetyl)-2-azatricyclo(9.4.0.0^(3,8))pentadeca-1(15),3(8),4,6,11,13-hexaen-5-yl)carbamateTiracizine [INN]ethyl N-[11-[2-(dimethylamino)acetyl]-5,6-dihydrobenzo[b][1]benzazepin-2-yl]carbamateTiracizine (INN)NCGC00160473-01
Properties
Computed structural properties
- XLogP
- 3.1
- Topological polar surface area
- 61.9 Ų
- Hydrogen bond donors
- 1
- Hydrogen bond acceptors
- 4
- Rotatable bonds
- 5
- Heavy atoms
- 27
- Formal charge
- 0
- Complexity
- 525
Physicochemical properties
- Melting point
- 127 · 127-128 °C(Solv: isopropanol (67-63-0))
- Boiling point
- 525.3 · 525.3±50.0 °C(Predicted)
- Density
- 1 · 1+-.0.06 g/cm3(Predicted)
- pka
- 13.42 · 13.42±0.20(Predicted)
- FDA UNII
- 9 UUO2T61K7 · 9UUO2T61K7
- ATC code
- 1 EB11 · C01EB11
Chemistry & industry
Pharmacology
ATC Code
C - Cardiovascular system
QC - Cardiovascular system
MeSH Pharmacological Classification
Agents used for the treatment or prevention of cardiac arrhythmias. They may affect the polarization-repolarization phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibers. Anti-arrhythmia agents are often classed into four main groups according to their mechanism of action: sodium channel blockade, beta-adrenergic blockade, repolarization prolongation, or calcium channel blockade.
A loosely defined grouping of drugs that have effects on psychological function. Here the psychotropic agents include the antidepressive agents, hallucinogens, and tranquilizing agents (including the antipsychotics and anti-anxiety agents).
Suppliers2 total
陕西缔都新材料有限公司81124267 17392282731 · [email protected]
湖北玖天生物医药科技有限公司027-88013699 17354350817 · [email protected]
Additional notes
DefinitionChEBI: Tiracizine is a dibenzooxazepine.
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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