HomeMCPWorkbenchSkills
HomeWorkbenchNotificationsMe
Huagongshe Open Program：[email protected]AI access: llms.txt · MCP GuidePrivacy Policy · Terms of Service · Supportv1.7.8
Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 71283Generated: October 31, 2026

Liothyronine hydrochloride

Liotironina · Liothyronine HCl · 3,3',5-Triiodo-L-thyronineHCl · 3,3',5-Triiodo-L-thyroninehydrochloride · O-(4-hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosine hydrochloride

https://huagongshe.com/en/chemical/71283

Liothyronine hydrochloride molecular structure

Identifiers & Physical Properties

CAS No.6138-47-2
Molecular formulaC15H13ClI3NO4
Average molar mass687.43 g/mol
Monoisotopic mass686.7667 g/mol
SMILESCl.N[C@@H](Cc1cc(I)c(Oc2ccc(O)c(I)c2)c(I)c1)C(=O)O
InChIKeyHFEMPWKWYHWPQX-YDALLXLXSA-N
PubChem CID71283
EC No.228-120-0
DTXSIDDTXSID10210299

Chemical & Physical Properties

Topological polar surface area92.8
Hydrogen bond donors4
Hydrogen bond acceptors5
Rotatable bonds5
Heavy atoms24
Formal charge0
Complexity402
alphaD29.5 +21.5° (c = 4.75 in a mixture of 1 vol N HCl and 2 vols ethanol)
FDA UNIIT66DHO0SET

Applications & Uses

Uses

Liothyronine hydrochloride is an active form of thyroid hormone. Liothyronine hydrochloride is a potent thyroid hormone receptors TRα and TRβ agonist with Kis of 2.33 nM for hTRα and hTRβ, respectively[1][2][3].