Benzenamine, 4-chloro-2-methoxy-

HCID 7143
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Basic information

CAS
93-50-5
Standard SMILES
COc1cc(Cl)ccc1N
InChIKey
WOXLPNAOCCIZGP-UHFFFAOYSA-N
Molecular formula
C7H8ClNO
Average molar mass
157.6 g/mol
Monoisotopic mass
157.0294416

Names & identifiers

Preferred name
Benzenamine, 4-chloro-2-methoxy-
IUPAC
4-chloro-2-methoxyaniline
English name
4-Chloro-2-anisidine hydrochloride
Molecular formula
C7H8ClNO
Molecular weight
157.6

Names & synonyms

4-chloro-2-methoxyaniline93-50-5Benzenamine, 4-chloro-2-methoxy-4-Chloro-o-anisidine4-chloro-2-methoxybenzenamineEINECS 202-251-3DTXSID5059088WOXLPNAOCCIZGP-UHFFFAOYSA-RefChem:561882DTXCID6048838202-251-3InChI=1/C7H8ClNO/c1-10-7-4-5(8)2-3-6(7)9/h2-4H,9H2,1H3
Show more names
4-Chloro-o-anisidine (NH2=1)4-Chloro-2-methoxyaniline 98%4-chloro-2-methoxy-benzenamin4-Chloro-2-methoxybenzeneamine
4-Chloro-2-methoxy-phenylaminep-Chloro-o-anisidine2-Amino-5-chloroanisoleMFCD06801386(4-Chloro-2-methoxyphenyl)amine4-chloro-2-methoxyphenylamine1-Amino-4-chloro-2-methoxybenzene2-methoxy-4-chloroaniline

Database identifiers

CAS
93-50-5
PubChem CID
7143
DTXSID
DTXSID5059088
UNII
TV9MZ8W6NF
EC Number
202-251-3
Nikkaji
J10.600C

Properties

Computed structural properties

XLogP
1.9
Topological polar surface area
35.3 Ų
Hydrogen bond donors
1
Hydrogen bond acceptors
2
Rotatable bonds
1
Heavy atoms
10

Physicochemical properties

Melting point
52 °C · 52°C
Boiling point
260 °C · 260°C (rough estimate)
Density
1.176 · 1.1760 (rough estimate)
refractive index
1.543 · 1.5430 (estimate)
storage temp.
2 · Keep in dark place,Inert atmosphere,2-8°C
solubility
Chloroform (Slightly), Methanol (Slightly)

Safety & regulation

GHS classification

GHS Classification · 6 items

Warning

H302 (25%): Harmful if swallowed [Warning Acute toxicity, oral]；H315 (75%): Causes skin irritation [Warning Skin corrosion/irritation]；H317 (25%): May cause an allergic skin reaction [Warning Sensitization, Skin]；H319 (75%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]；H335 (75%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]；H411 (25%): Toxic to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard]

P261, P264, P264+P265, P270, P271, P272, P273, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P333+P317, P337+P317, P362+P364, P391, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 4 reports by companies from 4 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.；Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

Not Classified

Hazard information

Hazard Classes and CategoriesAcute Tox. 4 (25%)；Skin Irrit. 2 (75%)；Skin Sens. 1 (25%)；Eye Irrit. 2A (75%)；STOT SE 3 (75%)；Aquatic Chronic 2 (25%)

Safety data

tsca
TSCA listed
hs_code
2921420090
risk_code
43
Signal word
Warning
Symbol(GHS)
GHS07
hazard_code
Xi

Chemistry & industry

Uses & manufacturing

General Manufacturing InformationBenzenamine, 4-chloro-2-methoxy-: INACTIVE

Applications

Uses4-Chloro-2-methoxyaniline is an important intermediate used for the synthesis of CXCR2 antagonists and some CD4-gp120 binding inhibitors.

Upstream & downstream products

Suppliers100 total

上海策嵘生物科技有限公司[email protected]
上海麦克林生化科技股份有限公司021-50706066 15221275939 · [email protected]
Changzhou Anxuan Chemical Co., Ltd+86-0519-89882563 +86-18961279162 · [email protected]
温州共赢化学有限公司+86-0086-577-64498589 +86-15355981851 · [email protected]
T&W GROUP021-61551611 13296011611 · [email protected]

Related reactions

24 records
New reaction record

Compound notes

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