Sodium Citrate Dihydrate
CITRIC ACID MONO · SODIUM CITRATE TRIBASIC DIHYDRATE · TRI-SODIUM CITRATE DIHYDRATE · SODIUM CITRATE, DIHYDRATE · SodiuM Citrate (AS) · SODIUM CITRATE TRISODIUM SALT DIHYDRATE · NATRII CITRAS · TRI-SODIUM CITRATE 2H2O
Identifiers & Physical Properties
| CAS No. | 6132-04-3 |
|---|---|
| Molecular formula | C6H9Na3O9 |
| Average molar mass | 294.1 g/mol |
| Monoisotopic mass | 293.99396471 g/mol |
| SMILES | O.O.O=C([O-])CC(O)(CC(=O)[O-])C(=O)[O-].[Na+].[Na+].[Na+] |
| InChIKey | NLJMYIDDQXHKNR-UHFFFAOYSA-K |
| PubChem CID | 71474 |
| ChEBI | CHEBI:32142 |
| EC No. | 612-118-5 |
| DTXSID | DTXSID1049437 |
Chemical & Physical Properties
| Topological polar surface area | 143 |
|---|---|
| Hydrogen bond donors | 3 |
| Hydrogen bond acceptors | 9 |
| Rotatable bonds | 2 |
| Heavy atoms | 18 |
| Formal charge | 0 |
| Complexity | 211 |
| Chemical classes | Metals -> Organic Acids, Metal Salts |
| Solubility | Solubility in water, g/100ml: 77H2O: 100 mg/mL720 g/L (25 ºC) |
| Animal Drugs | Pharmaceuticals -> UK Veterinary Medicines Directorate List |
| Decomposition | 150 °C |
| Physical Description | White odorless solid[Merck Index] Colorless odorless crystalline powder[Alfa Aesar MSDS]WHITE SOLID IN VARIOUS FORMS. |
| Melting point | >300 °C(lit.) |
| Density | 1.76 |
| Bulk density | 600kg/m3 |
| FEMA | 3026 | SODIUM CITRATE |
| Flash point | 173.9 °C |
| Storage conditions | Store at +5°C to +30°C. |
| Physical state | powder |
| pKa (acidity coefficient) | 6.40 |
| Color | white |
| Odor | Odorless |
| PH Range | 7.5 - 9 at 29.4 g/l at 25 °C |
| pH | 7.0-9.0 (25℃, 50mg/mL in H2O) |
| Biological source | synthetic |
| λmax | λ: 260 nm Amax: 0.01λ: 280 nm Amax: 0.01 |
| Merck | 14,8602 |
| BRN | 6104939 |
| Stability | Stable. Incompatible with bases, reducing agents, oxidizing agents. |
| Cosmetics Ingredients Functions | CHELATINGFRAGRANCEBUFFERING |
| InChI | 1S/C6H8O7.3Na.2H2O/c7-3(8)1-6(13,5(11)12)2-4(9)10/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)2*1H2/q3*+1/p-3 |
| InChIKey | NLJMYIDDQXHKNR-UHFFFAOYSA-K |
| SMILES | O.O.[Na+].[Na+].[Na+].OC(CC([O-])=O)(CC([O-])=O)C([O-])=O |
| LogP (partition coefficient) | -1.72 |
| CAS DataBase Reference | 6132-04-3(CAS DataBase Reference) |
| FDA UNII | B22547B95K |
| EPA Substance Registry System | 1,2,3-Propanetricarboxylic acid, 2-hydroxy-, trisodium salt, dihydrate (6132-04-3) |
| Absorption | ≤0.015 at 260nm≤0.015 at 280nm |
| UNSPSC Code | 41116107 |
| NACRES | NA.25 |
| GHS pictogram | GHS05,GHS07 |
| Signal word | Warning |
| GHS hazard statements | H318-H319 |
| GHS precautionary statements | P264-P280i-P305+P351+P338-P337+P313-P310a |
| Personal protective equipment (PPE) | Eyeshields, Gloves, type N95 (US) |
| Hazard symbols | Xi |
| Risk statements (R) | 37/38-41-36/37/38 |
| Safety statements (S) | 26-36/37/39-24/25-36 |
| Water hazard class (WGK) | 1 |
| RTECS number | GE7810000 |
| TSCA inventory status | Yes |
| Customs code | 2918 15 00 |
| Storage class | 11 - Combustible Solids |
| Toxicity | LD50 orally in Rabbit: > 8000 mg/kg |
Safety & Regulations
| GHS classification | This chemical does not meet GHS hazard criteria for 97% (520 of 536) of all reports.Not ClassifiedAggregated GHS information provided per 536 reports by companies from 4 notifications to the ECHA C&L Inventory. |
|---|---|
| Regulatory information | Chemical: 1,2,3-Propanetricarboxylic acid, 2-hydroxy-, trisodium salt, dihydrateTrisodium citrate dihydrate: Does not have an individual approval but may be used under an appropriate group standard |
| Other safety information | IMAP assessments - 1,2,3-Propanetricarboxylic acid, 2-hydroxy-, trisodium salt, dihydrate: Human health tier I assessment |
| Fire hazards | Combustible. |
| Hazards summary | An eye and respiratory tract irritant[ICSC] May cause irritation[Alfa Aesar MSDS] See Sodium citrate, anhydrous. |
| EPA Safer Chemical | Chemical: Sodium citrate, dihydrate |
| Chemical Dangers | The solution in water is a weak base. |
| Hazard Classes and Categories | Not Classified |
| Fire fighting | Use water spray, powder. |
| First aid measures | Fresh air, rest.Rinse and then wash skin with water and soap.First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.Rinse mouth. |
| Spillage disposal | Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Wash away remainder with plenty of water. |
| Eye Prevention | Wear safety spectacles. |
| Fire Prevention | NO open flames. |
| Inhalation Risk | Evaporation at 20 °C is negligiblea nuisance-causing concentration of airborne particles can, however, be reached quickly when dispersed. |
| Ingestion Prevention | Do not eat, drink, or smoke during work. |
| Inhalation Prevention | Use ventilation (not if powder). |
| Effects of Short Term Exposure | The substance is irritating to the eyes and respiratory tract. |
| Exposure routes | The substance can be absorbed into the body by inhalation of its aerosol and by ingestion. |
| Signs and Symptoms | Cough. Sore throat.Redness. |
| Personal protective equipment (PPE) | Eyeshields, Gloves, type N95 (US) |
| Water hazard class (WGK) | 1 |
| TSCA inventory status | Yes |
| RTECS number | GE7810000 |
| Customs code | 2918 15 00 |
| Toxicity | LD50 orally in Rabbit: > 8000 mg/kg |
| Risk statements (R) | 37/38-41-36/37/38 |
| Signal word | Warning |
| GHS pictogram | GHS05,GHS07 |
| Hazard symbols | Xi |
| Safety statements (S) | 26-36/37/39-24/25-36 |
| Storage class | 11 - Combustible Solids |
| GHS hazard statements | H318-H319 |
| GHS precautionary statements | P264-P280i-P305+P351+P338-P337+P313-P310a |
Applications & Uses
Uses
It can be used as Ph adjusting agents and emulsifying enhancers applied to jam, candy, jelly and ice cream; its combination with citric acid has an effect of alleviating tour; it also has effects on forming complex with metal ions. China rules that it can be applied to various types of food with appropriate usage according to the absolute necessity.It can be used as a food additive, as complex agent and buffering agent in electroplating industry; at the field of pharmaceutical industry, it is used for the manufacturing of anti-clotting drugs; and used as the detergent additives in light industry.It is used as the analysis agents used for chromatography analysis and can also used for preparing bacterial culture medium; moreover, it can also be applied into pharmaceutical industry.The product can be used for the flavoring processing of food, as stabilizers, buffers and deputy complex-forming agents in non-toxic electroplating industry; at pharmaceutical industry, it is used as anti-clotting agent, phlegm drugs and diuretics drugs. It can also be used in brewing, injection, newspaper and movies medicines.
Uses
Anticoagulant for collection of blood. In photography; as sequestering agent to remove trace metals; as emulsifier, acidulant and sequestrant in foods.
Uses
An anticoagulant also used as a biological buffer
Uses
Trisodium citrate dihydrate, is widely applied in food, beverages and fillers as a buffering, sequestering or an emulsifying agent. It used as an anticoagulant in blood transfusions, osmotic laxative, functional fluids, solvents cleaning, furnishing care products, laundry dishwashing products and cleaning automobile radiators.
Uses
Sodium citrate is chiefly used as a food additive, usually for flavor or as a preservative.
General Description
Sodium citrate tribasic dihydrate is the tribasic dihydrate sodium salt of citric acid.