Dipivefrin Hydrochloride

HCID 71486CAS 64019-93-8
Substructure searchFind similar structures

Basic information

Standard SMILES
CNCC(O)c1ccc(OC(=O)C(C)(C)C)c(OC(=O)C(C)(C)C)c1.Cl
InChIKey
VKFAUCPBMAGVRG-UHFFFAOYSA-N
Molecular formula
C19H30ClNO5
Average molar mass
387.9 g/mol
Monoisotopic mass
387.1812508

Names & identifiers

Preferred name
Dipivefrin Hydrochloride
IUPAC
[2-(2,2-dimethylpropanoyloxy)-4-[1-hydroxy-2-(methylamino)ethyl]phenyl] 2,2-dimethylpropanoate;hydrochloride
English name
Dipivefrin hydrochloride
Molecular formula
C19H30ClNO5
Molecular weight
387.8982

Names & synonyms

Dipivefrin hydrochloride64019-93-8Dipivefrin HCLDipivefrine hydrochlorideAKProDTXSID20454945QTH9UHV0K(1)-4-(1-Hydroxy-2-(methylamino)ethyl)-1,2-phenylene dipivalate hydrochlorideCHEBI:4647DTXCID0025494(RS)-4-(1-HYDROXY-2-(METHYLAMINO)ETHYL)-O-PHENYLENE DIPIVALATE HYDROCHLORIDEAlcon
Show more names
ProgateDiopinePivalephrineDipivefri ImpurityD6-Dipivefrine HClhydrochloride,(+-)-estedipivefrinhydrochloridedipivefrinehydrochlorideDipifrin (hydrochloride)
RefChem:56498dipivefrin hydrochloride, (+-)-Propanoic Acid, 2,2-dimethyl-, 4-(1-hydroxy-2-(methylamino)ethyl)-1,2-phenylene Ester, Hydrochloride,(+-)-Dipivefrin (hydrochloride)dipivefrine HClDipivefrine (hydrochloride)[2-(2,2-dimethylpropanoyloxy)-4-[1-hydroxy-2-(methylamino)ethyl]phenyl] 2,2-dimethylpropanoate;hydrochlorideDipivefrine hydrochloride (JAN)

Database identifiers

CAS
64019-93-8
PubChem CID
71486
DTXSID
DTXSID2045494
ChEMBL
CHEMBL1200833
ChEBI
CHEBI:4647
UNII
5QTH9UHV0K
EC Number
264-609-5

Properties

Computed structural properties

Topological polar surface area
84.9 Ų
Hydrogen bond donors
3
Hydrogen bond acceptors
6
Rotatable bonds
9
Heavy atoms
26

Physicochemical properties

Melting point
158 · 158-159°
storage temp.
-20 °C · Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility
Freely soluble in water, very soluble in methanol, freely soluble in ethanol (96 per cent) and in methylene chloride.
form
Solid
pka
8.4 · 8.40(at 25℃)
color
White to Off-White

Safety & regulation

GHS classification

GHS Classification · 5 items

Danger

H301 (100%): Toxic if swallowed [Danger Acute toxicity, oral]

P264, P270, P301+P316, P321, P330, P405, and P501 (click each P-code to see the statement)

The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.

Hazard information

Hazard Classes and CategoriesAcute Tox. 3 (100%)

Safety data

wgk
WGK 3
ridadr
UN 2811 6.1 / PGIII
hs_code
2922504500
Signal word
Danger
Symbol(GHS)
GHS06
Storage Class
6.1C - Combustible acute toxic Cat.3toxic compounds or compounds which causing chronic effects

Chemistry & industry

Pharmacology

MeSH Pharmacological ClassificationDrugs that bind to and activate adrenergic receptors.
Applications · 3 items

DescriptionDipivefrin hydrochloride is an antiglaucoma prothrombotic drug that is hydrolyzed to its active compound epinephrine by esterases in the cornea.

UsesDipivefrine Hydrochloride acts as an anti-glaucoma agent.

UsesAdrenergic (ophthalmic)

Suppliers50 total

南通飞宇生物科技有限公司0513-68819626 15152877458 · [email protected]
陕西缔都新材料有限公司81124267 17392282731 · [email protected]
广州佳途科技股份有限公司81960175 18933936954 · [email protected]
杭州摩库生物医药科技有限公司+86-057181025280; +8617767106207 · [email protected]
Dayang Chem (Hangzhou) Co.,Ltd.+86-0571-88938639 17705817739 · [email protected]

Additional notes

DefinitionChEBI: The hydrochloride salt of dipivefrin. It is used topically as eye drops to reduce intra-ocular pressure in the treatment of open-angle glaucoma or ocular hypertension.

Related reactions

3 records
New reaction record

Linked notes

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