(6R,7R)-7-[[(2E)-2-(2-amino-1,3-thiazol-4-yl)-2-(2-carboxylatopropan-2-yloxyimino)acetyl]amino]-8-oxo-3-(pyridin-1-ium-1-ylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate;hydron

HCID 71587366

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Basic information

CAS: 97148-38-4
Standard SMILES: CC(C)(O/N=C(/C(=O)N[C@@H]1C(=O)N2C(C(=O)[O-])=C(C[n+]3ccccc3)CS[C@H]12)c1csc(N)n1)C(=O)[O-].[H+]
InChIKey: ORFOPKXBNMVMKC-KZBLUZIOSA-N
Molecular formula: C22H22N6O7S2
Average molar mass: 546.6 g/mol
Monoisotopic mass: 546.09913904

Overview

See also: Ceftazidime anhydrous, (E)- (preferred).

Names & identifiers

Preferred name: (6R,7R)-7-[[(2E)-2-(2-amino-1,3-thiazol-4-yl)-2-(2-carboxylatopropan-2-yloxyimino)acetyl]amino]-8-oxo-3-(pyridin-1-ium-1-ylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate;hydron
IUPAC: (6R,7R)-7-[[(2E)-2-(2-amino-1,3-thiazol-4-yl)-2-(2-carboxylatopropan-2-yloxyimino)acetyl]amino]-8-oxo-3-(pyridin-1-ium-1-ylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate;hydron
English name: Ceftazidime EP Impurity B
Molecular formula: C22H22N6O7S2
Molecular weight: 546.58

Names & synonyms

(6R,7R)-7-[[(2E)-2-(2-amino-1,3-thiazol-4-yl)-2-(2-carboxylatopropan-2-yloxyimino)acetyl]amino]-8-oxo-3-(pyridin-1-ium-1-ylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate;hydronHydrogen (6R,7R)-7-{[(2E)-2-(2-amino-1,3-thiazol-4-yl)-2-{[(2-carboxylatopropan-2-yl)oxy]imino}acetyl]amino}-8-oxo-3-[(pyridin-1-ium-1-yl)methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylateCeftazidime EP Impurity BCeftazidime Impurity B(EP)Injection Cefotaxime impurity BE-Ceftazidime Ceftazidime Impurity BCeftazidime EP Impurity B(E-Ceftazidime)E-Ceftazidime Ceftazidime Impurity B (EP)Ceftazidime Impurity B (EP) (E-Ceftazidime)(6R,7R)-7-((E)-2-(2-aminothiazol-4-yl)-2-(((2-carboxypropan-2-yl)oxy)imino)acetamido)-8-oxo-3-(pyridin-1-ium-1-ylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate(6R,7R)-7-({(2E)-2-(2-Amino-1,3-thiazol-4-yl)-2-[(1-carboxy-1-methylethoxy)imino]ethanoyl}amino)-8-oxo-3-(1-pyridiniumylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate(6R,7R)-7-((E)-2-(2-Aminothiazol-4-yl)-2-(((2-carboxypropan-2-yl)oxy)imino)acetamido)-8-oxo-3-(pyridin-1-ium-1-ylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate? (Ceftazidime Impurity)

Database identifiers

CAS: 97148-38-4
PubChem CID: 71587366
DTXSID: DTXSID10242717
UNII: UU1494IX6R

Properties

Computed structural properties

Topological polar surface area: 248 Å²
Hydrogen bond donors: 3
Hydrogen bond acceptors: 12
Rotatable bonds: 7
Heavy atoms: 37
Formal charge: 0
Complexity: 1,020

Physicochemical properties

solubility: DMSO (Slightly), Methanol (Slightly, Sonicated)
form: Solid
pka: 2.426 · 2.426±0.50(predicted)
color: Pale Brown to Light Brown
Stability: Hygroscopic
FDA UNII: 1494 IX6R · UU1494IX6R

Chemistry & industry

Applications

UsesE-Ceftazidime is an impurity of Ceftazidime Pentahydrate (C244100); which is a third generation cephalosporin antibiotic.

Suppliers40 total

济南百隆化学有限公司[email protected] · [email protected]

杭州品高化工有限公司0571-87658025 · [email protected]

广州隽唐科技有限公司020-36607679 13502246435 · [email protected]

广州蓝宁生物科技有限公司15813355568 · [email protected]

Sinco Pharmachem (ShenZhen) R&D Co., Ltd.+86-18603013401 · [email protected]

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