Mepindolol
Basic information
- CAS
23694-81-7- Standard SMILES
Cc1cc2c(OCC(O)CNC(C)C)cccc2[nH]1- InChIKey
NXWGWUVGUSFQJC-UHFFFAOYSA-N- Molecular formula
- C15H22N2O2
- Average molar mass
- 262.35 g/mol
- Monoisotopic mass
- 262.16812795
Overview
Mepindolol is a member of indoles.
Names & identifiers
- Preferred name
- Mepindolol
- IUPAC
- 1-[(2-methyl-1H-indol-4-yl)oxy]-3-(propan-2-ylamino)propan-2-ol
- English name
- rac Mepindolol-d7
- Molecular formula
- C15H22N2O2
- Molecular weight
- 262.35
Names & synonyms
Mepindolol23694-81-7Mepindololum1-(Isopropylamino)-3-[(2-methylindol-4-yl)oxy]-2-propanol00Q31ER3681-(Isopropylamino)-3-((2-methylindol-4-yl)oxy)-2-propanolmepindololoRefChem:156511C07AA141-(isopropylamino)-3-(2-methylindol-4-yloxy)-2-propanol sulfatebis(4-(2-hydroxy-3-isopropylaminopropoxy)-2-methylindol) sulfate245-831-1
Show more names
rac Mepindolol-d7RaceMic MepindololDinotefuran Impurity 7-d7 RaceMic Mepindolol-d71-[isopropylamino]-3-[(2-methyl-indol-4-yl)oxy]-2-propanol1-(Isopropylamino)-3-[(2-methyl-1H-indol-4-yl)oxy]-2-propanol1-[(Isopropyl-d7)aMino]-3-[(2-Methylindol-4-yl)oxy]-2-propanol
rac Mepindolol1-(Isopropylamino)-3-((2-methyl-1H-indol-4-yl)oxy)propan-2-ol1-[(2-methyl-1H-indol-4-yl)oxy]-3-(propan-2-ylamino)propan-2-ol1-[(2-Methyl-1H-indol-4-yl)oxy]-3-[(propan-2-yl)amino]propan-2-olMepindolol (INN)MEPINDOLOL [INN]Mepindololum [INN-Latin]Mepindolol [INN:BAN]
Database identifiers
- CAS
23694-81-7- PubChem CID
- 71698
- DTXSID
DTXSID40865110- ChEMBL
CHEMBL65717- ChEBI
CHEBI:135082- UNII
- 00Q31ER368
- EC Number
- 245-831-1
- Nikkaji
- J20.368H
Properties
Computed structural properties
- XLogP
- 2.3
- Topological polar surface area
- 57.3 Ų
- Hydrogen bond donors
- 3
- Hydrogen bond acceptors
- 3
- Rotatable bonds
- 6
- Heavy atoms
- 19
- Formal charge
- 0
- Complexity
- 273
Experimental & physicochemical properties
LogP2.3
Human DrugsPharmaceuticals
Physicochemical properties
- Melting point
- 100 · 100-102° (Seeman). Also reported as 95-97° (Troxler)
- Boiling point
- 469.9 · 469.9±45.0 °C(Predicted)
- Density
- 1.131 · 1.131±0.06 g/cm3(Predicted)
- storage temp.
- Refrigerator
- solubility
- Chloroform (Slightly, Heated, Sonicated), Methanol (Slightly)
- pka
- 8.9 · pKa 8.90 (Uncertain)
- form
- Solid
- color
- Off-White to Pale Green
- FDA UNII
- 0 Q31ER368 · 00Q31ER368
- ATC code
- 7 AA14 · C07AA14
Chemistry & industry
Pharmacology
ATC Code
C - Cardiovascular system
QC - Cardiovascular system
MeSH Pharmacological Classification
Drugs that bind to but do not activate beta-adrenergic receptors thereby blocking the actions of beta-adrenergic agonists. Adrenergic beta-antagonists are used for treatment of hypertension, cardiac arrhythmias, angina pectoris, glaucoma, migraine headaches, and anxiety.
Uses & manufacturing
Use ClassificationPharmaceuticals
Applications
UsesMepindolol is a non-selective β-adrenoceptor blocking agent. Mepindolol is used in the treatment of glaucoma.
Uses(rac Mepindolol-d7) Mepindolol is a non-selective β-adrenoceptor blocking agent. Mepindolol is used in the treatment of glaucoma.
Additional notes
DefinitionChEBI: Mepindolol is a member of indoles.
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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