Seganserin
Basic information
- CAS
87729-89-3- Standard SMILES
Cc1nc2ccccn2c(=O)c1CCN1CCC(=C(c2ccc(F)cc2)c2ccc(F)cc2)CC1- InChIKey
ZGUPMFYFHHSNFK-UHFFFAOYSA-N- Molecular formula
- C29H27F2N3O
- Average molar mass
- 471.5 g/mol
- Monoisotopic mass
- 471.21221882
Overview
Seganserin is a small molecule drug. The usage of the INN stem '-anserin' in the name indicates that Seganserin is a serotonin receptor antagonist. Seganserin has a monoisotopic molecular weight of 471.21 Da.
Names & identifiers
- Preferred name
- Seganserin
- IUPAC
- 3-[2-[4-[bis(4-fluorophenyl)methylidene]piperidin-1-yl]ethyl]-2-methylpyrido[1,2-a]pyrimidin-4-one
- English name
- Seganserin
- Molecular formula
- C29H28F2N3O
- Molecular weight
- 472.5489264
Names & synonyms
Seganserin87729-89-3SeganserinaSeganserineSeganserinum197HL4EZCCDTXSID502365944H-Pyrido(1,2-a)pyrimidin-4-one, 3-(2-(4-(bis(4-fluorophenyl)methylene)-1-piperidinyl)ethyl)-2-methyl-, dihydrochloride3-(2-(4-(di-(4-fluorophenyl)methylene)-1-piperidinyl)ethyl)-1-methyl-4H-pyridol(1,2-a)-pyridimine-4-one dihydrochlorideRefChem:182234DTXCID801590853-[2-[4-[bis(4-fluorophenyl)methylidene]piperidin-1-yl]ethyl]-2-methylpyrido[1,2-a]pyrimidin-4-one
Show more names
3-[2-[4-[Bis(4-fluorophenyl)methylene]piperidino]ethyl]-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one
Seganserine [French]Seganserinum [Latin]Seganserina [Spanish]Seganserin [INN:BAN]UNII-197HL4EZCCSEGANSERIN [INN]SCHEMBL246745orb1745180
Database identifiers
- CAS
Properties
Computed structural properties
- XLogP
- 5.1
- Topological polar surface area
- 35.9 Ų
- Hydrogen bond donors
- 0
- Hydrogen bond acceptors
- 5
- Rotatable bonds
- 5
- Heavy atoms
- 35
- Formal charge
- 0
- Complexity
- 928
Physicochemical properties
- FDA UNII
- 197 HL4EZCC · 197HL4EZCC
Chemistry & industry
Applications
UsesSeganserin is an orally active 5-HT receptor antagonist with a plasma half-life of 26.1 ± 12.9 (S.D.) h. Seganserin can be utilized in neurological research[1].
Related reactions
3 records
Compound notes
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