Basic information
- CAS
19368-18-4- Standard SMILES
Cc1cccc(C)c1NC(=O)c1ccccc1C(=O)O- InChIKey
LLECMGGNFBKPRH-UHFFFAOYSA-N- Molecular formula
- C16H15NO3
- Average molar mass
- 269.29 g/mol
- Monoisotopic mass
- 269.10519334
Overview
Ftaxilide is a small molecule drug. The usage of the INN stem '-ilide' in the name indicates that Ftaxilide is a sematilide derivative class III antiarrhythmic. Ftaxilide has a monoisotopic molecular weight of 269.11 Da.
Names & identifiers
- Preferred name
- Ftaxilide
- IUPAC
- 2-[(2,6-dimethylphenyl)carbamoyl]benzoic acid
- English name
- Ftaxilide
- Molecular formula
- C16H15NO3
- Molecular weight
- 269.3
Names & synonyms
Ftaxilide19368-18-42',6'-Dimethylphthalanilic acidFtaxilidaFtaxilidumHistanormFtaxilide [INN:DCF]Ftaxilidum [INN-Latin]Ftaxilida [INN-Spanish]Phthalic 2,6-dimethylanilideDTXSID5046300FTAXILIDE [INN]
Show more names
MP-12-PFtaxilide, 10 mM in DMSON-(2,6-XYLYL)PHTHALAMIC ACIDBacterial,Inhibitor,Ftaxilide,inhibitN-(2,6-Dimethylphenyl)phthalamidic acid2-((2,6-Dimethylphenyl)carbamoyl)benzoic acid2-(2,6-Dimethylphenylcarbamoyl)benzoicacid,97%2-(2,6-DiMethylphenylcarbaMoyl)benzoic acid, 97%
MP 12NSC 16112NSC-16112Phthalanilic acid, 2',6'-dimethyl-BRN 26599927Z71845H3F2-(((2,6-Dimethylphenyl)amino)carbonyl)benzoic acidBenzoic acid, 2-(((2,6-dimethylphenyl)amino)carbonyl)-
Database identifiers
- CAS
19368-18-4- PubChem CID
- 71895
- DTXSID
Properties
Computed structural properties
- XLogP
- 3
- Topological polar surface area
- 66.4 Ų
- Hydrogen bond donors
- 2
- Hydrogen bond acceptors
- 3
- Rotatable bonds
- 3
- Heavy atoms
- 20
- Formal charge
- 0
- Complexity
- 359
Experimental & physicochemical properties
Collision Cross Section
159.2 Ų [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
165.29 Ų [M+Na]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
Physicochemical properties
- Melting point
- 188 · 188-189 °C(Solv: ethanol (64-17-5))
- Boiling point
- 375.3 · 375.3±42.0 °C(Predicted)
- Density
- 1.262 · 1.262±0.06 g/cm3(Predicted)
- RTECS
- 8490000 · TH8490000
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- Soluble in (10 mM DMSO).
- pka
- 3.45 · 3.45±0.36(Predicted)
- form
- Solid
- color
- White to off-white
- FDA UNII
- 7 Z71845H3F · 7Z71845H3F
- Symbol(GHS)
- 7 · GHS07
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
Warning
H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]
P264, P264+P265, P270, P273, P280, P301+P317, P305+P351+P338, P330, P337+P317, P391, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 38 reports by companies from 1 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Hazard information
Hazard Classes and CategoriesAcute Tox. 4 (100%)
Safety data
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- Hazard statements
- H303-H315-H319-H335
- Precautionary statements
- P261-P280a-P304+P340-P305+P351+P338-P405-P501a
Chemistry & industry
Applications
UsesIt is used as a novel antituberculosis agent.
Suppliers40 total
Career Henan Chemica Co+86-0371-86658258 +86-13203830695 · [email protected]
河南多贝化工有限公司0370-6999054 17550096163 · [email protected]
上海毕得医药科技股份有限公司400-1647117 13681763483 · [email protected]
浙江珲达生物科技有限公司0571-89903022 18679456698 · [email protected]
阿法埃莎（中国）化学有限公司400-6106006 · [email protected]
北京亿思研科技开发中心010-56645598 13366904824 · [email protected]
MedChemexpress LLC021-58955995 · [email protected]
BOC Sciences1-631-485-4226; 16314854226 · [email protected]
韶关市启程生物科技有限公司18122215013 · [email protected]
四川省维克奇生物科技有限公司028-81700200 18116577057 · [email protected]
天津普西唐生物医药科技有限公司010-60605840 · [email protected]
Sigma-Aldrich西格玛奥德里奇(上海)贸易有限公司021-61415566 800-8193336 · [email protected]
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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