Cotriptyline
Basic information
- CAS
34662-67-4- Standard SMILES
CN(C)CC(=O)C=C1c2ccccc2CCc2ccccc21- InChIKey
DRNINDKQWDOFMO-UHFFFAOYSA-N- Molecular formula
- C20H21NO
- Average molar mass
- 291.4 g/mol
- Monoisotopic mass
- 291.16231429
Overview
Cotriptyline is a small molecule drug. Cotriptyline has a monoisotopic molecular weight of 291.16 Da.
Names & identifiers
- Preferred name
- Cotriptyline
- IUPAC
- 1-(dimethylamino)-3-(2-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaenylidene)propan-2-one
- English name
- Cotriptyline
- Molecular formula
- C20H21NO
- Molecular weight
- 291.39
Names & synonyms
Cotriptyline34662-67-4CotriptilinaCotriptylinumKQJ4QI511CDTXSID50188221RefChem:128215DTXCID8011071210,11-dihydro-5H-dibenzo(a,d)cycloheptenylidene-5-3-dimethylamino-2-propanoneCotriptyline [INN:DCF]1-(dimethylamino)-3-(2-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaenylidene)propan-2-oneSD 2203-01
Show more names
1-(Dimethylamino)-3-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-2-propanone2-Propanone, 1-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-3-(dimethylamino)-
1-(Dimethylamino)-3-(10,11-dihydro-5H-dibenzo(a,d)cyclohepten-5-ylidene)-2-propanoneUNII-KQJ4QI511CCotriptylinum [INN-Latin]Cotriptilina [INN-Spanish]COTRIPTYLINE [INN]SCHEMBL2107759CHEMBL2106088SCHEMBL30801390
Database identifiers
- CAS
34662-67-4- PubChem CID
- 71935
- DTXSID
DTXSID50188221- ChEMBL
CHEMBL2106088- UNII
- KQJ4QI511C
- Nikkaji
- J19.427A
Properties
Computed structural properties
- XLogP
- 3.6
- Topological polar surface area
- 20.3 Ų
- Hydrogen bond donors
- 0
- Hydrogen bond acceptors
- 2
- Rotatable bonds
- 3
- Heavy atoms
- 22
- Formal charge
- 0
- Complexity
- 399
Physicochemical properties
- Boiling point
- 430.5 · 430.5±33.0 °C(Predicted)
- Density
- 1.143 · 1.143±0.06 g/cm3(Predicted)
- pka
- 6.8 · 6.80±0.28(Predicted)
- FDA UNII
- 4 QI511C · KQJ4QI511C
Chemistry & industry
Pharmacology
MeSH Pharmacological Classification
Mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions. Several MONOAMINE OXIDASE INHIBITORS are useful as antidepressants apparently as a long-term consequence of their modulation of catecholamine levels. The tricyclic compounds useful as antidepressive agents (ANTIDEPRESSIVE AGENTS, TRICYCLIC) also appear to act through brain catecholamine systems. A third group (ANTIDEPRESSIVE AGENTS, SECOND-GENERATION) is a diverse group of drugs including some that act specifically on serotonergic systems.
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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