Lofemizole

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Basic information

CAS: 65571-68-8
Standard SMILES: Cc1[nH]cnc1-c1ccc(Cl)cc1
InChIKey: MBKWNJVQSFBLQI-UHFFFAOYSA-N
Molecular formula: C10H9ClN2
Average molar mass: 192.64 g/mol
Monoisotopic mass: 192.045426

Overview

RN given refers to parent cpd; structure given in first source

Names & identifiers

Preferred name: Lofemizole
IUPAC: 4-(4-chlorophenyl)-5-methyl-1H-imidazole
English name: 4-(4-Chloro-phenyl)-5-methyl-1H-imidazole
Molecular formula: C10H9ClN2
Molecular weight: 192.64

Names & synonyms

Lofemizole65571-68-8LofemizolLofemizolumDTXSID1057797D8G23FPC3PDTXCID2031586RefChem:1539391H,4-(4-chlorophenyl)-5-methylimidazole265-818-44-(4-chlorophenyl)-5-methyl-1h-imidazole4-(4-CHLORO-PHENYL)-5-METHYL-1H-IMIDAZOLE

Show more names

Lofemizole, 10 mM in DMSO1H-IMidazole, 4-(4-chlorophenyl)-5-Methyl-1H-Imidazole, 5-(4-chlorophenyl)-4-methyl-N-(4-chloro-2-nitrophenyl)-N-nitrosoacetamide

Lofemizole [INN]MFCD00866069Lofemizol [INN-Spanish]Lofemizolum [INN-Latin]UNII-D8G23FPC3P4-(4-Chloro-phenyl)-5-methyl-1H-imidazole(Lofemizole)EINECS 265-818-4SCHEMBL35441

Database identifiers

CAS: 65571-68-8
PubChem CID: 71967
DTXSID: DTXSID1057797
ChEMBL: CHEMBL2111114
UNII: D8G23FPC3P
EC Number: 265-818-4
Nikkaji: J32.496E

Properties

Computed structural properties

XLogP: 2.8
Topological polar surface area: 28.7 Å²
Hydrogen bond donors: 1
Hydrogen bond acceptors: 1
Rotatable bonds: 1
Heavy atoms: 13
Formal charge: 0
Complexity: 166

Physicochemical properties

FDA UNII: 8 G23FPC3P · D8G23FPC3P
Symbol(GHS): 7 · GHS07
Signal word: Warning
Hazard statements: 319 · H319-H315-H335-H302
Precautionary statements: 264 · P264-P270-P301+P312-P330-P501-P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P

Safety & regulation

Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.

GHS classification

GHS Classification · 4 items

Warning

H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]

P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.

Hazard information

Hazard Classes and CategoriesAcute Tox. 4 (100%)

Safety data

Signal word: Warning
Symbol(GHS): GHS07
Hazard statements: H319-H315-H335-H302
Precautionary statements: P264-P270-P301+P312-P330-P501-P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P

Chemistry & industry

Applications

UsesAnti-inflammatory; analgesic; antipyretic.

Related reactions

0 records

New reaction record

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Compound notes

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