Basic information
- CAS
86880-51-5- Standard SMILES
N#Cc1ccccc1OCC(O)CNCCNC(=O)Cc1ccc(O)cc1- InChIKey
YARKMNAWFIMDKV-UHFFFAOYSA-N- Molecular formula
- C20H23N3O4
- Average molar mass
- 369.4 g/mol
- Monoisotopic mass
- 369.16885622
Overview
Epanolol is a member of acetamides.
Names & identifiers
- Preferred name
- Epanolol
- IUPAC
- N-[2-[[3-(2-cyanophenoxy)-2-hydroxypropyl]amino]ethyl]-2-(4-hydroxyphenyl)acetamide
- English name
- Epanolol
- Molecular formula
- C20H23N3O4
- Molecular weight
- 369.41
Names & synonyms
Epanolol86880-51-5EpanololumICI-141292ICI 141,2929KGC55KP6ADTXSID90868959Benzeneacetamide, N-(2-((3-(2-cyanophenoxy)-2-hydroxypropyl)amino)ethyl)-4-hydroxy-ICI-141,292N-(2-((3-(2-cyanophenoxy)-2-hydroxy-propyl)amino)ethyl)-2-(4-hydroxyphenyl)acetamideN-[2-[[3-(2-cyanophenoxy)-2-hydroxy-propyl]amino]ethyl]-2-(4-hydroxyphenyl)acetamideRefChem:590903
Show more names
EponololN-[2-[[3-(2-Cyanophenoxy)-2-hydroxypropyl]amino]ethyl]-4-hydroxybenzeneacetamideBenzeneacetamide, N-[2-[[3-(2-cyanophenoxy)-2-hydroxypropyl]amino]ethyl]-4-hydroxy-
N-(2-((3-(2-cyanophenoxy)-2-hydroxypropyl)amino)ethyl)-4-hydroxyphenylacetamideC07AB10DTXCID20817011VisacorEpanololum [Latin]ICI141292N-[2-[[3-(2-cyanophenoxy)-2-hydroxypropyl]amino]ethyl]-2-(4-hydroxyphenyl)acetamideVisacor;ICI141292
Database identifiers
- CAS
86880-51-5
Properties
Computed structural properties
- XLogP
- 0.9
- Topological polar surface area
- 115 Ų
- Hydrogen bond donors
- 4
- Hydrogen bond acceptors
- 6
- Rotatable bonds
- 10
- Heavy atoms
- 27
- Formal charge
- 0
- Complexity
- 485
Experimental & physicochemical properties
LogP0.92
Physicochemical properties
- Melting point
- 118 · 118-120°
- Boiling point
- 689.7 · 689.7±55.0 °C(Predicted)
- Density
- 1.28 · 1.28±0.1 g/cm3(Predicted)
- storage temp.
- -20 °C · Store at -20°C
- solubility
- Soluble in DMSO
- pka
- 9.87 · 9.87±0.15(Predicted)
- FDA UNII
- 9 KGC55KP6A · 9KGC55KP6A
- ATC code
- 7 AB10 · C07AB10
Chemistry & industry
Pharmacology
ATC Code
C - Cardiovascular system
QC - Cardiovascular system
MeSH Pharmacological Classification
Drugs that bind to but do not activate beta-adrenergic receptors thereby blocking the actions of beta-adrenergic agonists. Adrenergic beta-antagonists are used for treatment of hypertension, cardiac arrhythmias, angina pectoris, glaucoma, migraine headaches, and anxiety.
Drugs used in the treatment of acute or chronic vascular HYPERTENSION regardless of pharmacological mechanism. Among the antihypertensive agents are DIURETICS; (especially DIURETICS, THIAZIDE); ADRENERGIC BETA-ANTAGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CALCIUM CHANNEL BLOCKERS; GANGLIONIC BLOCKERS; and VASODILATOR AGENTS.
Drugs that mimic the effects of stimulating postganglionic adrenergic sympathetic nerves. Included here are drugs that directly stimulate adrenergic receptors and drugs that act indirectly by provoking the release of adrenergic transmitters.
Applications
UsesEpanolol is a adrenergic β-antagonist. Epanolol is used for treatment of hypertension, cardiac arrhythmias, angina pectoris, glaucoma, migraine headaches, and anxiety.
Suppliers14 total
北京华美互利生物化工010-56205725 · [email protected]
杭州摩库生物医药科技有限公司+86-057181025280; +8617767106207 · [email protected]
安耐吉化学&3A（安徽泽升科技有限公司）021-58432009 400-005-6266 · [email protected]
凯试(上海)科技有限公司021-50135380 · [email protected]
BOC Sciences
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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