Basic information
- CAS
71731-58-3- Standard SMILES
C[N@+]12CCCC[C@@H]1CCC(=C(c1cccs1)c1cccs1)C2.[Br-]- InChIKey
VKBNGRDAHSELMQ-KYSFMIDTSA-M- Molecular formula
- C19H24BrNS2
- Average molar mass
- 410.4 g/mol
- Monoisotopic mass
- 409.05335
Overview
Tiquizium bromide is a organic bromide salt of tiquizium. It is an antispasmodic drug used for the treatment of convulsion and hypermobility in gastritis, gastric ulcer, duodenal ulcer, enteritis, irritable bowel syndrome, gallbladder disease, biliary tract disease and urolithiasis. It has a role as a muscarinic antagonist, an anti-ulcer drug and an antispasmodic drug. It is a quaternary ammonium salt and an organic bromide salt. It contains a tiquizium.
Names & identifiers
- Preferred name
- Tiquizium Bromide
- IUPAC
- (5R,9aR)-7-(dithiophen-2-ylmethylidene)-5-methyl-1,2,3,4,6,8,9,9a-octahydroquinolizin-5-ium bromide
- English name
- Tiquizium bromide
- Molecular formula
- C19H24NS2.Br
- Molecular weight
- 410.44
Names & synonyms
tiquizium bromide71731-58-3ThiatonTiquizii bromidumBromuro de tiquizioBromure de tiquiziumHSR-902DTXSID2046757659K6049SF3-(Di-2-thienylmethylene)-5-methyl-trans-quinolizidinium bromideDTXCID0026757CHEBI:32232
Show more names
AsporaHS 902HSR 902GastirolTiquiziumTiquizium bromide USP/EP/BP2H-Quinolizinium, 3-(di-2-thienylmethylene)octahydro-5-methyl-, bromide, trans-
3-(Di(2-thienyl)methylene)-5-methyldecahydroquinolizinium bromidetrans-3-(Di-2-thienylmethylene)octahydro-5-methyl-2H-quinolizinium bromideRefChem:933097(5R,9aR)-7-(dithiophen-2-ylmethylidene)-5-methyl-1,2,3,4,6,8,9,9a-octahydroquinolizin-5-ium;bromideTiquizium (bromide)(5R,9aR)-3-[di(thiophen-2-yl)methylidene]-5-methyloctahydro-2H-quinolizin-5-ium bromideAdvastonBreiful
Database identifiers
- CAS
71731-58-3- PubChem CID
- 72159
- DTXSID
Properties
Computed structural properties
- Topological polar surface area
- 56.5 Ų
- Hydrogen bond donors
- 0
- Hydrogen bond acceptors
- 3
- Rotatable bonds
- 2
- Heavy atoms
- 23
- Formal charge
- 0
- Complexity
- 429
Physicochemical properties
- Melting point
- 278 · 278-281° (dec)
- storage temp.
- Refrigerator
- solubility
- DMSO (Slightly), Methanol (Slightly)
- form
- Solid
- color
- White to Off-White
- FDA UNII
- 659 K6049SF · 659K6049SF
Chemistry & industry
Applications
DescriptionTiquizium bromide is an anticholinergic agent useful in the treatment of various gastrointestinal syndromes including irritable colon.
UsesTiquizium Bromide is a antimuscarinic agent that was used on airway smooth muscle in vitro and in patients with chronic obstructive pulmonary disease.
Suppliers26 total
Dayang Chem (Hangzhou) Co.,Ltd.+86-0571-88938639 17705817739 · [email protected]
Sinoway Industrial co., ltd.+86-0592-5800732 +86-13806035118 · [email protected]
Hubei Datong Bio-Chemical Technology Co.,Ltd027-87666700 · [email protected]
Xiamen Eagle Chemical Limited Corporation+86-18900207489 · [email protected]
LUYUNJIA CHEMISTRY XIAMEN LIMITED+86-592-5360779 +86-13055435203
凯试（上海）科技有限公司021-50135380 · [email protected]
艾吉析科技（上海）有限公司17717235263 17717235263 · [email protected]
陕西缔都医药化工有限公司+86-29-81139210 +86-17392587031 · [email protected]
南京罗迈美生物科技有限公司[email protected]
深圳市森迪生物科技有限公司18126413629 0755-23311925 2355327053 · [email protected]
深圳市森迪生物科技有限公司
Related reactions
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Compound notes
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