Completing data — refresh the page later to see the latest
Basic information
- CAS
1476727-50-0- Standard SMILES
COC[C@@H](NC(=O)N1CC(=O)Nc2cc(OC)cnc21)c1ccc(OC(F)(F)F)c(F)c1- InChIKey
AWJSRXUQLSPAOI-CQSZACIVSA-N- Molecular formula
- C19H18F4N4O5
- Average molar mass
- 458.36 g/mol
Names & identifiers
- Preferred name
- TAK-915
- English name
- TAK-915
- Molecular formula
- C19H18F4N4O5
- Molecular weight
- 458.36
Names & synonyms
TAK-915(S)-N-(1-(3-fluoro-4-(trifluoromethoxy)phenyl)-2-methoxyethyl)-7-methoxy-2-oxo-2,3-dihydropyrido[2,3-b]pyrazine-4(1H)-carboxamidePyrido[2,3-b]pyrazine-4(1H)-carboxamide, N-[(1S)-1-[3-fluoro-4-(trifluoromethoxy)phenyl]-2-methoxyethyl]-2,3-dihydro-7-methoxy-2-oxo-
Database identifiers
- CAS
1476727-50-0- PubChem CID
- 72190879
- ChEMBL
CHEMBL4060569- UNII
- 0M4DME62Y9
- Nikkaji
- J3.685.660B
Properties
Physicochemical properties
- Boiling point
- 651 · 651.0±55.0 °C(Predicted)
- Density
- 1.42 · 1.420±0.06 g/cm3(Predicted)
- pka
- 11.2 · 11.20±0.20(Predicted)
- form
- Solid
- color
- Light yellow to yellow
- FDA UNII
- 0 M4DME62Y9 · 0M4DME62Y9
Chemistry & industry
Applications
UsesTAK-915 is a potent, selective, brain-penetrant and orally active phosphodiesterase 2A (PDE2A) inhibitor with an IC50 of 0.61 nM. TAK-915 is >4100-fold more selectivity for PDE2A than PDE1A. TAK-915 has the potential for neuropsychiatric and neurodegenerative disorders treatment[1][2].
Suppliers7 total
銳迪國際科技有限公司18024082417 · [email protected]
无锡捷化医药科技有限公司0510-83588313-811 18800520310 · [email protected]
上海陶术生物科技股份有限公司+1-781-999-5354; +1-00000000000 · [email protected]
HANGZHOU LEAP CHEM CO., LTD.+86-571-87711850 +86-15355479329 · [email protected]
陕西缔都医药有限责任公司81148925 17391631969 · [email protected]
HANGZHOU CLAP TECHNOLOGY CO.,LTD86-571-88216897,88216896 13588875226 · [email protected]
南京世洲生物科技有限公司025-85560043 15850508050 · [email protected]
Related reactions
0 records
No reaction records under the current filter.
Compound notes
Loading…