LF 1695
Basic information
- CAS
86187-86-2- Standard SMILES
CC1CCN(c2ccc(N)cc2C(=O)c2ccc(Cl)cc2)CC1- InChIKey
RTHJIPJVGHYRMG-UHFFFAOYSA-N- Molecular formula
- C19H21ClN2O
- Average molar mass
- 328.8 g/mol
- Monoisotopic mass
- 328.134241
Overview
structure given in first source
Names & identifiers
- Preferred name
- LF 1695
- IUPAC
- [5-amino-2-(4-methylpiperidin-1-yl)phenyl]-(4-chlorophenyl)methanone
- English name
- LF 1695
- Molecular formula
- C19H21ClN2O
- Molecular weight
- 328.84
Names & synonyms
86187-86-2LF 1695LF-1695DTXSID90235440RefChem:153250DTXCID90157931Methanone, (5-amino-2-(4-methyl-1-piperidinyl)phenyl)(4-chlorophenyl)-[5-amino-2-(4-methylpiperidin-1-yl)phenyl]-(4-chlorophenyl)methanone2-(4-Methyl-1-piperidinyl)-5-aminophenyl-(4-chlorophenyl)methanoneImupedoneCHEMBL35827orb1702027
Show more names
LF 1695, 10 mM in DMSOLF1695|||LF-1695|||LF 16955-Amino-4'-chloro-2-(4-methyl-1-piperidinyl)benzophenone[5-Amino-2-(4-methyl-1-piperidinyl)phenyl](4-chlorophenyl)methanone[2-(4-methyl-1-piperidinyl)-5-aminophenyl]-(4-chlorophenyl)-methanone
SCHEMBL10355571LF1695AKOS040747076HY-108161CS-0027458T25705[5-amino-2-(4-methyl-1-piperidyl)phenyl]-(4-chlorophenyl)methanone[5-Amino-2-(4-methylpiperidin-1-yl)phenyl](4-chlorophenyl)methanone
Database identifiers
- CAS
86187-86-2- PubChem CID
- 72226
- DTXSID
DTXSID90235440- ChEMBL
CHEMBL35827- Nikkaji
- J409.636C
Properties
Computed structural properties
- XLogP
- 4.6
- Topological polar surface area
- 46.3 Ų
- Hydrogen bond donors
- 1
- Hydrogen bond acceptors
- 3
- Rotatable bonds
- 3
- Heavy atoms
- 23
- Formal charge
- 0
- Complexity
- 400
Physicochemical properties
- Boiling point
- 529.163 · 529.163±50.00 °C(Press: 760.00 Torr)(predicted)
- Density
- 1.2 · 1.200±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
- pka
- 6.331 · 6.331±0.10(predicted)
Chemistry & industry
Applications
DescriptionLF 1695 is a synthetic immunomodulator.
UsesLF 1695 is an immunomodulator. LF 1695 enhances the proliferative response of T cells by increasing the production of IL2 (interleukin-2) or the expression of the IL2 receptor. LF 1695 also increases CONA-induced inhibitory activity in human lymphocytes. LF 1695 can be used to study the proliferative and inhibitory activity of T cell subpopulations, as well as their role in immune regulation[1].
Related reactions
0 records
No reaction records under the current filter.
Compound notes
Loading…