Fmoc-Phg-OH

HCID 7269367CAS 102410-65-1

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Basic information

Standard SMILES: O=C(N[C@H](C(=O)O)c1ccccc1)OCC1c2ccccc2-c2ccccc21
InChIKey: PCJHOCNJLMFYCV-NRFANRHFSA-N
Molecular formula: C23H19NO4
Average molar mass: 373.4 g/mol
Monoisotopic mass: 373.13140809

Overview

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Names & identifiers

Preferred name: Fmoc-Phg-OH
IUPAC: (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-2-phenylacetic acid
English name: Fmoc-L-phenylglycine
Molecular formula: C23H19NO4
Molecular weight: 373.4

Names & synonyms

Fmoc-Phg-OHDTXSID80428480RefChem:1085493DTXCID50379314102410-65-1Fmoc-L-phenylglycine(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-phenylacetic acidMFCD00155632FMOC-(S)-PHENYLGLYCINE(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-2-phenylacetic acidN-Fmoc-L-2-phenylglycineSCHEMBL119848

Show more names

FMOC-L-PHG-OHFMOC-PHENYLGLYCINEFmoc-PhgFMOC-L-PHGFMOC-D-PHG-OH,98%RARECHEM EM WB 0180RARECHEM EM WB 0181FMOC-(PHENYL)GLY-OH

Benzeneacetic acid, alpha-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-, (alphaS)-CS-W019988N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-2-phenylglycine(2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-2-phenylacetic acidM03224(S)-[(9H-Fluoren-9-ylmethoxycarbonylamino)]-phenyl-acetic acid(2S)-2-(9H-fluoren-CHEMBL356179

Database identifiers

CAS: 102410-65-1
PubChem CID: 7269367
DTXSID: DTXSID80428480
ChEMBL: CHEMBL356179
Nikkaji: J1.037.204F

Properties

Computed structural properties

XLogP: 4.3
Topological polar surface area: 75.6 Å²
Hydrogen bond donors: 2
Hydrogen bond acceptors: 4
Rotatable bonds: 6
Heavy atoms: 28
Formal charge: 0
Complexity: 537

Physicochemical properties

Melting point: 175 · 175-180 °C
Boiling point: 606.3 · 606.3±50.0 °C(Predicted)
alpha: 81 · 81 º (c=1% in DMF)
Density: 1.299 · 1.299±0.06 g/cm3(Predicted)
refractive index: 81 ° · 81 ° (C=1, DMF)
storage temp.: 2 · 2-8°C
solubility: soluble in Methanol
pka: 3.39 · 3.39±0.10(Predicted)
form: Solid
color: White to Almost white
optical activity: 20 · [α]20/D +81±3°, c = 1% in DMF
BRN: 5309005 · 5309005
Major Application: peptide synthesis
InChI: 1S/C23H19NO4/c25-22(26)21(15-8-2-1-3-9-15)24-23(27)28-14-20-18-12-6-4-10-16(18)17-11-5-7-13-19(17)20/h1-13,20-21H,14H2,(H,24,27)(H,25,26)/t21-/m0/s1
InChIKey: PCJHOCNJLMFYCV-NRFANRHFSA-N
SMILES: OC(=O)[C@@H](NC(=O)OCC1c2ccccc2-c3ccccc13)c4ccccc4
CAS DataBase Reference: 102410 · 102410-65-1(CAS DataBase Reference)
UNSPSC Code: 12352209 · 12352209
NACRES: 26 · NA.26
Symbol(GHS): 7 · GHS07
Signal word: Warning
Hazard statements: 302 · H302-H315-H319-H335
Precautionary statements: 261 · P261-P302+P352-P304+P340-P305+P351+P338
PPE: 95 · Eyeshields, Gloves, type N95 (US)
Safety Statements: 22 · 22-24/25
WGK Germany: 3 · 3
F: 10 · 10
HS Code: 2924 · 2924 29 70
HazardClass: IRRITANT
Storage Class: 11 · 11 - Combustible Solids

Safety & regulation

Safety data

F: 10
PPE: Eyeshields, Gloves, type N95 (US)
wgk: 3
hs_code: 2924 29 70
Signal word: Warning
Symbol(GHS): GHS07
safety_code: 22-24/25
hazard_class: IRRITANT
Storage Class: 11 - Combustible Solids
Hazard statements: H302-H315-H319-H335
Precautionary statements: P261-P302+P352-P304+P340-P305+P351+P338

Chemistry & industry

Applications

Usespeptide synthesis

Upstream & downstream products

Upstream raw materials

Suppliers50 total

北京华美互利生物化工010-56205725 · [email protected]

梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]

郑州阿尔法化工有限公司+86-18530059196 · [email protected]

上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]

江苏吉泰肽业科技有限公司051580855088 18762539991 · [email protected]

Related reactions

3 records

New reaction record

HRID 734207As reactantuspto-grants-2009_09

HRID 1295634As reactantuspto-grants-2007_07

HRID 1684817As reactantuspto-grants-2012_04

Linked notes

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