Basic information
- CAS
18437-58-6- Standard SMILES
Cc1cc(N)ccn1- InChIKey
GNCLPNMQEGMNTG-UHFFFAOYSA-N- Molecular formula
- C6H8N2
- Average molar mass
- 108.14 g/mol
- Monoisotopic mass
- 108.06874826
Names & identifiers
- Preferred name
- 4-Amino-2-methylpyridine
- IUPAC
- 2-methylpyridin-4-amine
- English name
- 4-Amino-2-picoline
- Molecular formula
- C6H8N2
- Molecular weight
- 108.14
Names & synonyms
Show more names
Database identifiers
- CAS
18437-58-6- PubChem CID
- 728670
- DTXSID
DTXSID90902504- EC Number
- 625-782-6
- Nikkaji
- J82.750I
Properties
Computed structural properties
- XLogP
- 0.4
- Topological polar surface area
- 38.9 Ų
- Hydrogen bond donors
- 1
- Hydrogen bond acceptors
- 2
- Rotatable bonds
- 0
- Heavy atoms
- 8
- Formal charge
- 0
- Complexity
- 72
Physicochemical properties
- Melting point
- 93 · 93-97 °C
- Boiling point
- 143 °C/9mmHg · 143°C/9mmHg(lit.)
- Density
- 1.068 · 1.068±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- solubility
- Soluble in methanol.
- pka
- 9 · 9+-.0.30(Predicted)
- form
- Powder
- color
- Tan
- InChI
- 1S/C6H8N2/c1-5-4-6(7)2-3-8-5/h2-4H,1H3,(H2,7,8)
- InChIKey
- GNCLPNMQEGMNTG-UHFFFAOYSA-N
- SMILES
- Cc1cc(N)ccn1
- CAS DataBase Reference
- 18437 · 18437-58-6(CAS DataBase Reference)
- UNSPSC Code
- 12352100 · 12352100
- NACRES
- 22 · NA.22
- Symbol(GHS)
- 5 · GHS05,GHS07
- Signal word
- Danger
- Hazard statements
- 302 · H302-H315-H318-H335
- Precautionary statements
- 280 · P280-P301+P312+P330-P302+P352-P305+P351+P338+P310
- target organs
- Respiratory system
- PPE
- 95 · dust mask type N95 (US), Eyeshields, Gloves
- Hazard Codes
- Xn,T,Xi
- Risk Statements
- 22 · 22-37/38-41-36/37/38-20/21/22
- Safety Statements
- 26 · 26-36/39-36
- WGK Germany
- 3 · 3
- Hazard Note
- Harmful
- HazardClass
- IRRITANT, TOXIC
- HS Code
- 29333990 · 29333990
- Storage Class
- 11 · 11 - Combustible Solids
- Hazard Classifications
- 4 OralEye · Acute Tox. 4 OralEye Dam. 1Skin Irrit. 2STOT SE 3
Safety & regulation
GHS classification
GHS Classification
This chemical does not meet GHS hazard criteria for 2.3% (1 of 43) of reports.
Danger
H302 (97.7%): Harmful if swallowed [Warning Acute toxicity, oral];H315 (97.7%): Causes skin irritation [Warning Skin corrosion/irritation];H318 (93%): Causes serious eye damage [Danger Serious eye damage/eye irritation];H335 (95.3%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]
P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P354+P338, P317, P319, P321, P330, P332+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 43 reports by companies from 6 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.;Reported as not meeting GHS hazard criteria per 1 of 43 reports by companies.;There are 5 notifications provided by 42 of 43 reports by companies with hazard statement code(s).;Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.
Hazard information
Safety data
- PPE
- dust mask type N95 (US), Eyeshields, Gloves
- wgk
- 3
- hs_code
- 29333990
- risk_code
- 22-37/38-41-36/37/38-20/21/22
- Signal word
- Danger
- Symbol(GHS)
- GHS05,GHS07
- hazard_code
- Xn,T,Xi
- hazard_note
- Harmful
- safety_code
- 26-36/39-36
- hazard_class
- IRRITANT, TOXIC
- Storage Class
- 11 - Combustible Solids
- target organs
- Respiratory system
- Hazard statements
- H302-H315-H318-H335
- Hazard Classifications
- Acute Tox. 4 OralEye Dam. 1Skin Irrit. 2STOT SE 3
- Precautionary statements
- P280-P301+P312+P330-P302+P352-P305+P351+P338+P310
Chemistry & industry
Applications
Uses4-Amino-2-methylpyridine is used to prepare 2-methyl-pyridin-4-ol; nitrate at 20°C.
Upstream & downstream products
Upstream raw materials
Downstream products
Suppliers100 total
Related reactions
Compound notes
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