4-Amino-2-methylpyridine

HCID 728670

Basic information

CAS
18437-58-6
Standard SMILES
Cc1cc(N)ccn1
InChIKey
GNCLPNMQEGMNTG-UHFFFAOYSA-N
Molecular formula
C6H8N2
Average molar mass
108.14 g/mol
Monoisotopic mass
108.06874826

Names & identifiers

Preferred name
4-Amino-2-methylpyridine
IUPAC
2-methylpyridin-4-amine
English name
4-Amino-2-picoline
Molecular formula
C6H8N2
Molecular weight
108.14

Names & synonyms

4-Amino-2-methylpyridine18437-58-6RefChem:517685625-782-64-Amino-2-picoline2-methylpyridin-4-amine2-methyl-4-aminopyridineMFCD001865092-methyl-4-pyridinamine4-pyridinamine, 2-methyl-2-Methyl-pyridin-4-ylamine4-amino-picoline
Show more names
AURORA 24654-Amino-2-methyLAKOS BBS-000067404-AMINO-6-PICOLINE4-AMino-2-Methylpyrdine2-Methyl-4-amine-pyridin
4-amino-2-methyl-pyridine4-Amino-2-methylpyridine, 97%DTXSID90902504CL0056STK695662AKOS000271091PS-92882-methyl-4-pyridylamine

Database identifiers

CAS
18437-58-6
PubChem CID
728670
DTXSID
DTXSID90902504
EC Number
625-782-6
Nikkaji
J82.750I

Properties

Computed structural properties

XLogP
0.4
Topological polar surface area
38.9 Ų
Hydrogen bond donors
1
Hydrogen bond acceptors
2
Rotatable bonds
0
Heavy atoms
8

Physicochemical properties

Melting point
93 · 93-97 °C
Boiling point
143 °C/9mmHg · 143°C/9mmHg(lit.)
Density
1.068 · 1.068±0.06 g/cm3(Predicted)
storage temp.
Keep in dark place,Inert atmosphere,Room temperature
solubility
Soluble in methanol.
pka
9 · 9+-.0.30(Predicted)

Safety & regulation

GHS classification

GHS Classification · 6 items

This chemical does not meet GHS hazard criteria for 2.3% (1 of 43) of reports.

Danger

H302 (97.7%): Harmful if swallowed [Warning Acute toxicity, oral];H315 (97.7%): Causes skin irritation [Warning Skin corrosion/irritation];H318 (93%): Causes serious eye damage [Danger Serious eye damage/eye irritation];H335 (95.3%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P354+P338, P317, P319, P321, P330, P332+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 43 reports by companies from 6 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.;Reported as not meeting GHS hazard criteria per 1 of 43 reports by companies.;There are 5 notifications provided by 42 of 43 reports by companies with hazard statement code(s).;Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

Hazard information

Hazard Classes and CategoriesAcute Tox. 4 (97.7%);Skin Irrit. 2 (97.7%);Eye Dam. 1 (93%);STOT SE 3 (95.3%)

Safety data

PPE
dust mask type N95 (US), Eyeshields, Gloves
wgk
3
hs_code
29333990
risk_code
22-37/38-41-36/37/38-20/21/22
Signal word
Danger
Symbol(GHS)
GHS05,GHS07

Chemistry & industry

Applications

Uses4-Amino-2-methylpyridine is used to prepare 2-methyl-pyridin-4-ol; nitrate at 20°C.

Suppliers100 total

梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
INTATRADE GmbH+49 3493/605464 · [email protected]
爱斯特(成都)生物制药股份有限公司+86-28-85122536 85324413 · [email protected]
韶远科技(上海)有限公司021-50795510 4000665055 · [email protected]

Related reactions

33 records

Compound notes

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