Basic information
- CAS
4238-41-9- Standard SMILES
Cc1ccc(S(=O)(=O)N[C@@H](CCCCN)C(=O)CCl)cc1.Cl- InChIKey
YFCUZWYIPBUQBD-ZOWNYOTGSA-N- Molecular formula
- C14H22Cl2N2O3S
- Average molar mass
- 369.3 g/mol
- Monoisotopic mass
- 368.0728191
Overview
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Names & identifiers
- Preferred name
- p-N-(7-Amino-1-chloro-2-oxohept-3-yl)toluenesulphonamide
- IUPAC
- N-[(3S)-7-amino-1-chloro-2-oxoheptan-3-yl]-4-methylbenzenesulfonamide;hydrochloride
- English name
- TLCK
- Molecular formula
- C14H22Cl2N2O3S
- Molecular weight
- 369.3
Names & synonyms
Tosyllysine chloromethyl ketone hydrochlorideEINECS 224-199-0p-N-(7-Amino-1-chloro-2-oxohept-3-yl)toluenesulphonamide(S)-N-(5-Amino-1-(chloroacetyl)pentyl)-p-toluenesulphonamide monohydrochlorideNSC 727366Nalpha-p-Tosyl-L-lysine chloromethyl ketone hydrochloride(S)-N-[5-amino-1-(chloroacetyl)pentyl]-p-toluenesulphonamide monohydrochlorideRefChem:858136224-199-0224-266-44272-74-6TLCK hydrochloride
Show more names
TLCK (Tosyl-L-lysyl-chloromethane hydrochloride)TLCK HCLTOS-LYS-CMK HCLTOSYL-L-LYSYL-CHLOROMETHANE HCLTOSYL-L-LYSINE CHLOROMETHYLKETONE HCLN-ALPHA-TOSYL-LYS-CHLOROMETHYLKETONE HCLNALPHA-P-TOSYL-L-LYSIN CHLOROMETYL KETONE
(S)-N-(7-Amino-1-chloro-2-oxoheptan-3-yl)-4-methylbenzenesulfonamide hydrochlorideTLCKN-alpha-p-Tosyl-L-lysine chloromethyl ketone hydrochloride(3S)-1-Chloro-3-tosylamido-7-amino-2-heptanone hydrochlorideTos-Lys-chloromethylketone HClNa-p-Tosyl-L-lysine chloromethyl ketone hydrochlorideN-alpha-Tosyl-L-lysine chloromethyl ketone hydrochlorideDTXSID3045807
Properties
Computed structural properties
- Topological polar surface area
- 97.6 Ų
- Hydrogen bond donors
- 3
- Hydrogen bond acceptors
- 5
- Rotatable bonds
- 9
- Heavy atoms
- 22
- Formal charge
- 0
- Complexity
- 414
Physicochemical properties
- Melting point
- 165 °C · ~165 °C (dec.)
- storage temp.
- 2 · 2-8°C
- solubility
- 2 O: · H2O: 50 mg/mL
- form
- powder
- color
- white to pink
- Water Solubility
- Soluble in water
- InChI
- 1S/C14H21ClN2O3S.ClH/c1-11-5-7-12(8-6-11)21(19,20)17-13(14(18)10-15)4-2-3-9-16;/h5-8,13,17H,2-4,9-10,16H2,1H3;1H/t13-;/m0./s1
- InChIKey
- YFCUZWYIPBUQBD-ZOWNYOTGSA-N
- SMILES
- [S](=O)(=O)(N[C@@H](CCCC[N+H3])C(=O)CCl)c1ccc(cc1)C.[Cl-]
- UNSPSC Code
- 12352200 · 12352200
- NACRES
- 77 · NA.77
- Symbol(GHS)
- 7 · GHS07
- Signal word
- Danger
- Hazard statements
- 315 · H315-H319-H335
- Precautionary statements
- 261 · P261-P280a-P304+P340-P305+P351+P338-P405-P501a
- Hazard Codes
- Xi
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
Warning
H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 39 reports by companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Warning
H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
Hazard information
Hazard Classes and Categories
Skin Irrit. 2 (100%)
Skin Irrit. 2 (100%)
Safety data
- F
- 10-21
- wgk
- 3
- rtecs
- XT5160000
- risk_code
- 36/37/38
- Signal word
- Danger
- Symbol(GHS)
- GHS07
- hazard_code
- Xi
- safety_code
- 26-36
- Storage Class
- 11 - Combustible Solids
- Hazard statements
- H315-H319-H335
- Precautionary statements
- P261-P280a-P304+P340-P305+P351+P338-P405-P501a
Chemistry & industry
Applications
UsesInhibitor of papain and trypsin
Suppliers12 total
上海海皋科技有限公司021-57646680 18306277365 · [email protected]
杭州思诺达医药科技有限责任公司0571-87213919 17306812703 · [email protected]
北京绿百草科技发展有限公司010-61136123 · [email protected]
怀化市冰峰化工有限公司0745-2866851 17711757908 · [email protected]
斯百全化学（上海）有限公司021-021-021-67601398-809-809-809 15221380277 · [email protected]
TargetMol 中国（陶术生物）400-821-0310 15002144251 · [email protected]
韶远科技（上海）有限公司4000665055 · [email protected]
上海源叶生物科技有限公司18916372613 · [email protected]
杭州肽佳生物科技有限公司0571-87213919 15967184799 · [email protected]
江苏洪珉药业有限公司18221292452 · [email protected]
陕西缔都医药化工有限公司+86-29-81139210 17389186172 · [email protected]
北京百灵威科技有限公司18210857532 18210857532 · [email protected]
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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