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2-Hydroxy-2-phenylacetohydrazide

HCID 73126
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Basic information

CAS
2443-66-5
Standard SMILES
NNC(=O)C(O)c1ccccc1
InChIKey
FWTGUGVETHVGTL-UHFFFAOYSA-N
Molecular formula
C8H10N2O2
Average molar mass
166.18 g/mol
Monoisotopic mass
166.07422757

Names & identifiers

Preferred name
2-Hydroxy-2-phenylacetohydrazide
IUPAC
2-hydroxy-2-phenylacetohydrazide
English name
Mandelic acid hydrazide
Molecular formula
C8H10N2O2
Molecular weight
166.18

Names & synonyms

2-Hydroxy-2-phenylacetohydrazideHydroxy(phenyl)acetic acid hydrazideRefChem:473092674-144-32443-66-5Mandelic acid hydrazideMandelhydrazineMandelic acid, hydrazideMFCD00038133Mandelhydrazide2-hydroxy-2-phenyl-acetohydrazide2-???-1-phenylethan-1-ol
Show more names
AKOS BC-1667ASISCHEM D13400MANDELIC HYDRAZIDETIMTEC-BB SBB007729SPECS AN-068/40184273Mandelicacidhydrazide,97%α-Phenyl-α-hydroxyacetohydrazide
MandelohydrazideTimTec1_001774Hydroxy(phenyl)acetohydrazideOprea1_383456CHEMBL338836SCHEMBL2978269DTXSID80947303HMS1539A14

Database identifiers

CAS
2443-66-5
PubChem CID
73126
DTXSID
DTXSID80947303
ChEMBL
CHEMBL338836
EC Number
674-144-3
Nikkaji
J41.633I

Properties

Computed structural properties

XLogP
-0.4
Topological polar surface area
75.4 Ų
Hydrogen bond donors
3
Hydrogen bond acceptors
3
Rotatable bonds
2
Heavy atoms
12
Formal charge
0
Complexity
155

Physicochemical properties

Melting point
134 · 134-136°C
Boiling point
420.9 · 420.9±38.0 °C(Predicted)
Density
1.277 · 1.277±0.06 g/cm3(Predicted)
storage temp.
2 · 2-8°C(protect from light)
pka
12.07 · 12.07±0.36(Predicted)
Appearance
White to off-white Solid
BRN
2096197 · 2096197
CAS DataBase Reference
2443 · 2443-66-5(CAS DataBase Reference)
Symbol(GHS)
7 · GHS07
Signal word
Warning
Hazard statements
315 · H315-H319-H335
Precautionary statements
261 · P261-P280a-P304+P340-P305+P351+P338-P405-P501a
Risk Statements
36 · 36/37/38
Safety Statements
26 · 26-36/37/39
RTECS
7450000 · OO7450000

Safety & regulation

Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.

GHS classification

GHS Classification · 4 items

Warning

H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]

P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 6 reports by companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Hazard information

Hazard Classes and CategoriesSkin Irrit. 2 (100%)

Safety data

tsca
T
rtecs
OO7450000
risk_code
36/37/38
Signal word
Warning
Symbol(GHS)
GHS07
safety_code
26-36/37/39
Hazard statements
H315-H319-H335
Precautionary statements
P261-P280a-P304+P340-P305+P351+P338-P405-P501a

Chemistry & industry

Applications · 1 item

UsesMaleic hydrazide is used in organic synthesis and as a crop growth control agent. For example, it is used to prepare a dragon fruit preservative, comprising the following raw materials in parts by weight: 10-20 parts tea saponin, 1-3 parts salicylic acid, 0.5-2 parts tea polyphenols, 0.5-3 parts tea tree oil, 1-2 parts lemongrass oil, 5-10 parts ascorbic acid, 3-5 parts chitosan, 3-6 parts maleic hydrazide, and 1-3 parts konjac glucomannan. This invention uses a variety of preservative and antibacterial raw materials and surfactants, allowing the preservative to form a thin film on the fruit surface. This allows the preserved dragon fruit to retain its nutrients for a long time without loss, providing advantages such as antiseptic, preservation, sterilization, prevention of water loss, and significant preservation effects, thus offering a better storage method for fruit. This product can be used to prepare a preservative for cut flowers of Paphiopedilum orchids. The preservative includes the following types: flower preservative, stamen preservative, leaf preservative, stem preservative, and vase preservative. Each type of preservative includes one or more of the following components: sucrose, L1-MCP, aluminum sulfate, dimethylaminosuccinic acid, maleic acid hydrazide, aminotriacetic acid, and deionized water. Each type of preservative can be applied alone, in combination, or in combination with other products. Each type of preservative effectively promotes the healthy growth of each part of the cut flower, extends the growth cycle of the corresponding part, ensures the overall beauty of the cut flower, and maintains the overall perfection of the plant. It is a comprehensive and effective preservative for cut flowers of Paphiopedilum orchids.

Upstream & downstream products

Upstream raw materials

Methyl DL-mandelate

Downstream products

Salicylidene mandelhydrazone

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Related reactions

1 records
New reaction record
HRID 2416620 reaction equation
HRID 2416620As reactantuspto-grants-2004_11

Compound notes

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